Accounting Policies [Abstract] Accounting Policies [Abstract] Accounts Payable And Accrued Liabilities Disclosure [Text Block] Accrued Expenses Accounts Payable Current Accounts payable Accounts Receivable Prepaid Expense and Other Current Assets Accounts Receivable Prepaid Expense And Other Current Assets Accounts receivable, prepaid expenses, and other current assets Accrued Clinical Trial Costs Current Accrued Clinical Trial Costs Current Accrued clinical trial costs Accrued Liabilities Current Accrued expenses Total accrued expenses Accrued Liabilities Current And Noncurrent Noncurrent accrued interest Accrued Manufacturing Expenses Current Accrued Manufacturing Expenses Current Accrued contract manufacturing expenses Additional Paid In Capital Additional paid-in capital Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Agreement Termination Date Agreement Termination Date Agreement termination date Allocated Share Based Compensation Expense Stock-based compensation expense Amendment Flag Amendment Flag Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount Antidilutive securities excluded from computation of diluted weighted-average shares outstanding Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis] Antidilutive Securities [Axis] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Name [Domain] Antidilutive Securities, Name [Domain] Assets Total Assets [Abstract] ASSETS Assets Current Total current assets Assets Current [Abstract] Current assets: Award Type [Axis] Award Type [Axis] Cash And Cash Equivalents At Carrying Value Cash and cash equivalents - End of period Cash and cash equivalents - Beginning of period Cash and cash equivalents Cash And Cash Equivalents Period Increase Decrease Net increase (decrease) in cash and cash equivalents Cash Flow Noncash Investing And Financing Activities Disclosure [Abstract] Supplemental disclosures of noncash investing and financing activities: Class Of Stock [Domain] Class of Stock [Domain] Commitment, Contingency And Related Party Transactions [Abstract] Commitment Contingency And Related Party Transactions [Abstract] Commitment, Contingency And Related Party Transactions [Abstract] Commitments And Contingencies Commitments Common Stock Capital Shares Reserved For Future Issuance Common stock reserved for issuance Common Stock [Member] Common Stock [Member] Common Stock Par Or Stated Value Per Share Common stock, par value Common Stock Shares Authorized Common stock, shares designated Common Stock Shares Issued Common stock issued Common stock, shares issued Common Stock Shares Outstanding Common stock, shares outstanding Common Stock Value Common stock, $0.0001 par value; 132,000,000 shares and designated, 793,561 and 785,531 shares issued and outstanding at March 31, 2014 and December 31, 2013, respectively Contractual Obligation Contractual obligation to share in losses of the Company Conversion Of Accrued Interest And Convertible Notes Payable Conversion Of Accrued Interest And Convertible Notes Payable Conversion of accrued interest and convertible notes payable Conversion Of Stock Amount Issued 1 Conversion of redeemable convertible preferred stock into common stock Convertible Notes Payable Current Convertible promissory notes payable to shareholders Convertible Notes Payable [Member] Convertible Notes Payable [Member] Convertible Preferred Stock Shares Issued Upon Conversion Convertible preferred stock, shares issued upon conversion Convertible Promissory Notes [Member] Convertible Promissory Notes [Member] Convertible Promissory Notes [Member] Costs And Expenses [Abstract] Operating expenses: Current Fiscal Year End Date Current Fiscal Year End Date Debt Conversion Converted Instrument Rate Debt instrument percentage Debt Disclosure [Abstract] Debt Disclosure [Abstract] Debt Disclosure [Text Block] Convertible Notes Payable to Shareholders Debt Instrument Accrued Interest Debt Instrument Accrued Interest Accrued interest Debt Instrument [Axis] Debt Instrument [Axis] Debt Instrument Existing Investors [Member] Debt Instrument Existing Investors [Member] Existing Investors [Member] Debt Instrument Face Amount Debt instrument, Aggregate amount Debt Instrument Interest Rate Stated Percentage Debt instrument interest rate percentage Debt Instrument [Line Items] Debt Instrument [Line Items] Debt Instrument Name [Domain] Debt Instrument, Name [Domain] Debt Instrument New Investor Member Debt Instrument New Investor [Member] New Investor [Member] Debt Instrument [Table] Schedule of Long-term Debt Instruments [Table] Debt Instrument Term Debt instrument, Period Depreciation Depletion And Amortization Depreciation and amortization Development Stage Enterprise Deficit Accumulated During Development Stage Deficit accumulated during the development stage Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] Disclosure of Compensation Related Costs, Share-based Payments [Abstract] Disclosure Of Compensation Related Costs Share Based Payments [Text Block] Stock Option Plan Document And Entity Information [Abstract] Document And Entity Information [Abstract] Document And Entity Information [Abstract] Document Fiscal Period Focus Document Fiscal Period Focus Document Fiscal Year Focus Document Fiscal Year Focus Document Period End Date Document Period End Date Document Type Document Type Earnings Loss Allocated To Participating Securities Earnings Loss Allocated To Participating Securities Allocation of net loss to participating securities Earnings Per Share [Abstract] Net loss per share attributable to common stockholders: Earnings Per Share Basic And Diluted Basic and diluted Earnings Per Share [Text Block] Net Loss Per Share Attributable to Common Stockholders Employee Related Liabilities Current Accrued compensation and benefits Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] Enterprise Wide Disclosures [Line Items] Enterprise Wide Disclosures [Line Items] Enterprise Wide Disclosures [Line Items] Enterprise Wide Disclosures [Table] Enterprise Wide Disclosures [Table] Enterprise Wide Disclosures [Table] Entity Central Index Key Entity Central Index Key Entity Common Stock Shares Outstanding Entity Common Stock, Shares Outstanding Entity Filer Category Entity Filer Category Entity Incorporation Date Of Incorporation Date of Company's incorporation Entity Registrant Name Entity Registrant Name Equity Component [Domain] Equity Component [Domain] Equity Issuance Dates Common stock issuance date Equity Method Investments And Cost Method Investments [Abstract] Equity Method Investments And Cost Method Investments [Abstract] Equity Method Investments And Cost Method Investments [Abstract] Fair value of preferred stock warrants issued in connection with debt. Fair Value Adjustment Of Preferred Stock Warrants Fair value of preferred stock warrants issued in connection with debt Fair Value Adjustment Of Warrants Change in carrying value of preferred stock warrant liability Decrease in value of preferred stock warrant liability Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value Measurements, Recurring and Nonrecurring [Table] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items] Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Table] Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Table] Fair Value Assets Measured On Nonrecurring Basis Valuation Techniques [Text Block] Fair Value of Preferred Stock Warrant Liability Calculated by Black-Scholes Option Pricing Model Fair Value Assumptions Expected Dividend Rate Expected dividend rate Fair Value Assumptions Expected Term Expected life Fair Value Assumptions Expected Volatility Rate Expected volatility Fair Value Assumptions Risk Free Interest Rate Risk-free interest rate Fair Value By Fair Value Hierarchy Level [Axis] Fair Value, Hierarchy [Axis] Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Fair Value Disclosures [Text Block] Fair Value Measurements Fair Value Inputs Level 1 [Member] Quoted Prices in Active Markets for Identical Assets (Level 1) [Member] Fair Value Inputs Level 2 [Member] Significant Other Observable Inputs (Level 2) [Member] Fair Value Inputs Level 3 [Member] Significant Unobservable Inputs (Level 3) [Member] Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Table] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Text Block] Reconciliation of Company's Liabilities Measured at Fair Value on Recurring Basis Using Unobservable Inputs (Level3) Fair Value Measurements Fair Value Hierarchy [Domain] Fair Value Hierarchy [Domain] Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Gain Loss Included In Earnings Decrease in fair value recorded in other income Fair Value Measurement With Unobservable Inputs Reconciliations Recurring Basis Liability Value Liabilities measured at fair value on recurring basis using unobservable inputs, Ending balance Liabilities measured at fair value on recurring basis using unobservable inputs, Beginning balance Federal Income Tax Expense Benefit Continuing Operations Federal income tax benefit Gain Loss On Sale Of Property Plant Equipment Loss on disposal of property and equipment General And Administrative Expense General and administrative General And Administrative Expense [Member] General and administrative [Member] Income Loss From Continuing Operations Including Portion Attributable To Noncontrolling Interest Net loss attributable to common stockholders - basic and diluted Income Loss From Continuing Operations Per Basic And Diluted Share Net loss per share attributable to common stockholders - basic and diluted Income Statement [Abstract] Income Statement [Abstract] Income Statement Location [Axis] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Income Tax Disclosure [Text Block] Income Taxes Increase (decrease) accounts receivable, prepaid expenses and other current assets Increase Decrease Accounts Receivable Prepaid Expenses And Other Current Assets Accounts receivable, prepaid expenses and other current assets Increase Decrease In Accounts Payable Accounts payable Increase Decrease In Accrued Liabilities Accrued expenses Increase Decrease In Operating Capital [Abstract] Changes in operating assets and liabilities: Increase In Restricted Cash Increase in restricted cash Initial Offering Period IPO closure date Interest Expense Interest expense Interest Paid Net Supplemental cash flow information - Interest paid Investment Income Interest Interest income I P O [Member] IPO [Member] Liabilities And Stockholders Equity Total Liabilities Current Total current liabilities Liabilities Current [Abstract] Current liabilities: Liabilities Fair Value Disclosure Preferred stock warrant liability Liabilities Noncurrent Total long-term liabilities Liabilities Noncurrent [Abstract] Long-term liabilities: Loans Payable Current Current portion of loan payable Long Term Loans Payable Loan payable - net of current portion Maximum [Member] Maximum [Member] Minimum [Member] Minimum [Member] Minimum percentage of outstanding notes to trigger payment after maturity date. Minimum Percentage Of Outstanding Notes To Trigger Payment After Maturity Date Minimum percentage of outstanding notes to trigger payment after maturity date Money Market Funds At Carrying Value Money market funds Nature Of Operations Nature of Business and Operations Net Cash Provided By Used In Financing Activities [Abstract] Cash flows from financing activities: Net Cash Provided By Used In Financing Activities Continuing Operations Net cash provided by (used in) financing activities Net Cash Provided By Used In Investing Activities [Abstract] Cash flows from investing activities: Net Cash Provided By Used In Investing Activities Continuing Operations Net cash used in investing activities Net Cash Provided By Used In Operating Activities [Abstract] Cash flows from operating activities: Net Cash Provided By Used In Operating Activities Continuing Operations Net cash used in operating activities Net Income Loss Net loss Net loss Net Income Loss Available To Common Stockholders Basic Net loss attributable to common stockholders Noncash Or Part Noncash Acquisition Value Of Assets Acquired 1 Property and equipment acquired under capital lease Non Employee Awards [Member] Non Employee Awards [Member] Non Employee Awards [Member] Nonoperating Income Expense [Abstract] Other income (expense): Operating Expenses Total operating expenses Options To Purchase Common Stock [Member] Options To Purchase Common Stock [Member] Options to Purchase Common Stock [Member] Organization Consolidation And Presentation Of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Other Accrued Liabilities Current Accrued expenses Other Assets Noncurrent Other assets Other Liabilities Noncurrent Other Other Nonoperating Income Expense Total other income (expense) - net Paid In Kind Interest Noncash interest expense Payables And Accruals [Abstract] Payables and Accruals [Abstract] Payments Of Stock Issuance Costs Cash paid for deferred financing costs Payments To Acquire Property Plant And Equipment Purchases of property and equipment Plan Name [Axis] Plan Name [Axis] Plan Name [Domain] Plan Name [Domain] Preferred Stock Accretion Of Redemption Discount Accretion of preferred stock issuance costs to redemption value Preferred Stock Conversion Basis Preferred stock conversion basis Preferred Stock [Member] Preferred Stock [Member] Proceeds From Convertible Debt Proceeds from issuance of convertible promissory notes Proceeds From Issuance Initial Public Offering Proceeds from issuance of common stock Proceeds From Issuance Of Common Stock Proceeds from sale of common stock Proceeds From Issuance Of Redeemable Convertible Preferred Stock Proceeds from sale of redeemable convertible preferred stock - net of issuance costs Proceeds From Notes Payable Proceeds from loans payable Proceeds From Sale Of Machinery And Equipment Proceeds from sale of equipment Proceeds From Sale Of Property Plant And Equipment Proceeds from sale of property and equipment Property Plant And Equipment Net Property and equipment - Net Range [Axis] Range [Axis] Range [Member] Range [Domain] Redeemable Convertible Preferred Stock [Member] Redeemable Convertible Preferred Stock [Member] Related Party Transaction Expenses From Transactions With Related Party Fees recorded offsetting research and development expenses Related Party Transactions [Abstract] Related Party Transactions [Abstract] Related Party Transactions Disclosure [Text Block] Related Party Transactions Repayments Of Long Term Capital Lease Obligations Payments on capital lease Repayments Of Notes Payable Payments on loans payable Research And Development Expense Research and development Research And Development Expense [Member] Research and development [Member] Research And Development In Process Noncash research and development expense Revenues Revenue Sale Of Stock Name Of Transaction [Domain] Sale of Stock, Name of Transaction [Domain] Scenario Forecast [Member] Scenario, Forecast [Member] Scenario Unspecified [Domain] Scenario, Unspecified [Domain] Schedule Of Accrued Liabilities Table [Text Block] Schedule of Accrued Expenses Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block] Potentially Dilutive Securities Excluded from Computation of Diluted Weighted-Average Shares Outstanding Schedule Of Earnings Per Share Basic And Diluted Table [Text Block] Schedule of Basic and Diluted Net Loss Per Common Share Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block] Schedule of Stock-based Compensation Expense Schedule Of Fair Value Assets And Liabilities Measured On Recurring Basis Table [Text Block] Summary of Financial Assets and Liabilities Measured on Recurring Basis at Fair Value Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule Of Share Based Compensation Stock Options Activity Table [Text Block] Summary of Stock Option Activity for Employee, Directors and Nonemployee Awards under 2007 Stock Incentive Plan ("2007 Plan")