<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2021 Workiva-->
<!--r:6ec10cbf-7b82-4c2c-a526-5fcdd70cf6ab,g:dddaeb41-1f7d-4ee6-8f20-c9d7fa2cab2f-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://darebioscience.com/role/CoverPage" xlink:type="simple" xlink:href="dare-20210930.xsd#CoverPage"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/CoverPage" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_09e23998-e843-4936-9abe-436291a31d4c" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_DocumentType_09e23998-e843-4936-9abe-436291a31d4c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentQuarterlyReport_be8d4927-abf6-4add-a013-8b09201f06c1" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentQuarterlyReport"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_DocumentQuarterlyReport_be8d4927-abf6-4add-a013-8b09201f06c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_bf1426f7-a0db-4cfe-86ac-d89da522caae" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_DocumentPeriodEndDate_bf1426f7-a0db-4cfe-86ac-d89da522caae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentTransitionReport_d303e2b5-dd11-4051-9ca6-8552c9e7bfd7" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentTransitionReport"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_DocumentTransitionReport_d303e2b5-dd11-4051-9ca6-8552c9e7bfd7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_74eea548-3d06-47b7-90e0-71564a40eaea" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityRegistrantName_74eea548-3d06-47b7-90e0-71564a40eaea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_d14db4f4-8723-4ff1-8df6-932d21751ccf" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityIncorporationStateCountryCode_d14db4f4-8723-4ff1-8df6-932d21751ccf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_998acb18-3b4f-4b14-9d93-f49bd7c973f0" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityFileNumber_998acb18-3b4f-4b14-9d93-f49bd7c973f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_9d5d6ab1-6c97-45f5-ae00-0349da957e5d" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityTaxIdentificationNumber_9d5d6ab1-6c97-45f5-ae00-0349da957e5d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_57cb021a-0965-42a3-9131-81cd2a0a6466" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityAddressAddressLine1_57cb021a-0965-42a3-9131-81cd2a0a6466" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine2_586292d6-8eaa-41a6-b79f-66647426181d" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressAddressLine2"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityAddressAddressLine2_586292d6-8eaa-41a6-b79f-66647426181d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_0acb7662-d2c8-4dfa-a60c-3fd09c777769" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityAddressCityOrTown_0acb7662-d2c8-4dfa-a60c-3fd09c777769" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_f2c3231a-3edc-40fc-845f-2deacad62fec" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityAddressStateOrProvince_f2c3231a-3edc-40fc-845f-2deacad62fec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_1970ff44-e521-4459-9252-6f2de0d131de" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_CityAreaCode_1970ff44-e521-4459-9252-6f2de0d131de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_33bbc09d-faec-4f9e-a2c9-b9d845fca9a3" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_LocalPhoneNumber_33bbc09d-faec-4f9e-a2c9-b9d845fca9a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_da2a7dec-afa0-4208-8659-3ca6dd522389" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityAddressPostalZipCode_da2a7dec-afa0-4208-8659-3ca6dd522389" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_0f4511d4-e3e6-444b-8366-d57473f32e7b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_Security12bTitle_0f4511d4-e3e6-444b-8366-d57473f32e7b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_80e3be28-d316-4a3f-9b67-f215cc0f4d3a" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_TradingSymbol_80e3be28-d316-4a3f-9b67-f215cc0f4d3a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus_8bbad573-1998-49e6-a78b-c6c54176ebf8" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCurrentReportingStatus"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityCurrentReportingStatus_8bbad573-1998-49e6-a78b-c6c54176ebf8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInteractiveDataCurrent_a5527438-c626-4a7e-95c1-c7cb701bbace" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityInteractiveDataCurrent"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityInteractiveDataCurrent_a5527438-c626-4a7e-95c1-c7cb701bbace" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory_4a5e844a-fe7f-4651-adc5-c91f9cc83cfe" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityFilerCategory"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityFilerCategory_4a5e844a-fe7f-4651-adc5-c91f9cc83cfe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitySmallBusiness_e8882596-70fd-4cf0-8dc9-92c08f4ce0da" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntitySmallBusiness"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntitySmallBusiness_e8882596-70fd-4cf0-8dc9-92c08f4ce0da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_552efbbb-2c41-44dd-a76d-22ea6a827c7d" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityEmergingGrowthCompany_552efbbb-2c41-44dd-a76d-22ea6a827c7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany_64ac3e76-66c1-4166-b8a3-b2c70f23e8b5" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityShellCompany"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityShellCompany_64ac3e76-66c1-4166-b8a3-b2c70f23e8b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_88cbbf2c-071c-4b82-8fe0-b257245badda" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCommonStockSharesOutstanding"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_88cbbf2c-071c-4b82-8fe0-b257245badda" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_3c6cb6f2-9fe1-4992-89c7-983487ecb0f3" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_AmendmentFlag_3c6cb6f2-9fe1-4992-89c7-983487ecb0f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalYearFocus_2710a4cc-0644-4403-9fb7-6b5214019526" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentFiscalYearFocus"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_DocumentFiscalYearFocus_2710a4cc-0644-4403-9fb7-6b5214019526" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalPeriodFocus_aff1f841-9bfc-40ad-aa2a-83c089194aee" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentFiscalPeriodFocus"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_DocumentFiscalPeriodFocus_aff1f841-9bfc-40ad-aa2a-83c089194aee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_78875133-4c37-4403-8e4f-6fbddab042c9" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_EntityCentralIndexKey_78875133-4c37-4403-8e4f-6fbddab042c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate_416eb984-05be-4189-b860-4d2a3725afb1" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CurrentFiscalYearEndDate"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_0a0ad647-6f97-475f-98ee-21aa69e7c636" xlink:to="loc_dei_CurrentFiscalYearEndDate_416eb984-05be-4189-b860-4d2a3725afb1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/CondensedConsolidatedBalanceSheets" xlink:type="simple" xlink:href="dare-20210930.xsd#CondensedConsolidatedBalanceSheets"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/CondensedConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_f4017fe0-3088-4ee5-a054-3734f87ad460" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsAbstract_2fd64efc-f45b-4c14-b2d7-eadaf526bc65" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f4017fe0-3088-4ee5-a054-3734f87ad460" xlink:to="loc_us-gaap_AssetsAbstract_2fd64efc-f45b-4c14-b2d7-eadaf526bc65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrentAbstract_dbeafca0-3f1d-416f-9b65-6556041f92cd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_2fd64efc-f45b-4c14-b2d7-eadaf526bc65" xlink:to="loc_us-gaap_AssetsCurrentAbstract_dbeafca0-3f1d-416f-9b65-6556041f92cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_8ac071b1-859e-49df-857a-7388d4bcad2e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_dbeafca0-3f1d-416f-9b65-6556041f92cd" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_8ac071b1-859e-49df-857a-7388d4bcad2e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherReceivablesNetCurrent_1c5986ad-869f-4648-9012-23357f5f1fad" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherReceivablesNetCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_dbeafca0-3f1d-416f-9b65-6556041f92cd" xlink:to="loc_us-gaap_OtherReceivablesNetCurrent_1c5986ad-869f-4648-9012-23357f5f1fad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseCurrent_5baaa789-3a7a-4c65-adde-958539cb7757" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PrepaidExpenseCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_dbeafca0-3f1d-416f-9b65-6556041f92cd" xlink:to="loc_us-gaap_PrepaidExpenseCurrent_5baaa789-3a7a-4c65-adde-958539cb7757" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_7346b4d3-0db1-44e5-924b-7eae426481b9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_dbeafca0-3f1d-416f-9b65-6556041f92cd" xlink:to="loc_us-gaap_AssetsCurrent_7346b4d3-0db1-44e5-924b-7eae426481b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_04917f67-b7d0-4151-894c-e2618fe7c450" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_2fd64efc-f45b-4c14-b2d7-eadaf526bc65" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_04917f67-b7d0-4151-894c-e2618fe7c450" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_07981e8c-4bb9-4eeb-9048-102193c5b7dd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_2fd64efc-f45b-4c14-b2d7-eadaf526bc65" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_07981e8c-4bb9-4eeb-9048-102193c5b7dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_e7c610b7-4ff7-4911-8606-cc1559b714d5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Assets"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_2fd64efc-f45b-4c14-b2d7-eadaf526bc65" xlink:to="loc_us-gaap_Assets_e7c610b7-4ff7-4911-8606-cc1559b714d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_ca1afa13-5647-46cc-9d57-18183efa6ec6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f4017fe0-3088-4ee5-a054-3734f87ad460" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_ca1afa13-5647-46cc-9d57-18183efa6ec6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_9b07d213-81f6-4247-aeae-f21b0c670553" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_ca1afa13-5647-46cc-9d57-18183efa6ec6" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_9b07d213-81f6-4247-aeae-f21b0c670553" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_097d8c53-1364-41cc-8b8d-dc0931262004" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9b07d213-81f6-4247-aeae-f21b0c670553" xlink:to="loc_us-gaap_AccountsPayableCurrent_097d8c53-1364-41cc-8b8d-dc0931262004" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_dc4162c8-69fa-4a68-aff2-f67dbd9ed8a5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9b07d213-81f6-4247-aeae-f21b0c670553" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_dc4162c8-69fa-4a68-aff2-f67dbd9ed8a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_DeferredGrantFundingCurrent_0ae46892-a8c1-4f10-87b6-c610883cc0b9" xlink:href="dare-20210930.xsd#dare_DeferredGrantFundingCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9b07d213-81f6-4247-aeae-f21b0c670553" xlink:to="loc_dare_DeferredGrantFundingCurrent_0ae46892-a8c1-4f10-87b6-c610883cc0b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesPayableCurrent_53f143fc-5c77-41bf-a966-1f9839a77db9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesPayableCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9b07d213-81f6-4247-aeae-f21b0c670553" xlink:to="loc_us-gaap_NotesPayableCurrent_53f143fc-5c77-41bf-a966-1f9839a77db9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent_6d2b2bf2-1158-4f06-99ce-ac32b7ac7fd4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9b07d213-81f6-4247-aeae-f21b0c670553" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent_6d2b2bf2-1158-4f06-99ce-ac32b7ac7fd4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_298fc93b-95e9-4cdc-bc61-e844ef458c48" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9b07d213-81f6-4247-aeae-f21b0c670553" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_298fc93b-95e9-4cdc-bc61-e844ef458c48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_bee5d202-7cd3-442f-bf0c-baf6e7b32648" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9b07d213-81f6-4247-aeae-f21b0c670553" xlink:to="loc_us-gaap_LiabilitiesCurrent_bee5d202-7cd3-442f-bf0c-baf6e7b32648" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_f91bb417-7430-4b7e-89b4-f621cbcbfc9e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ContractWithCustomerLiabilityNoncurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_ca1afa13-5647-46cc-9d57-18183efa6ec6" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_f91bb417-7430-4b7e-89b4-f621cbcbfc9e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_73da5d19-9395-4ef1-a809-1bcc162fa1c2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_ca1afa13-5647-46cc-9d57-18183efa6ec6" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_73da5d19-9395-4ef1-a809-1bcc162fa1c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_f34a1d51-311f-48e7-a5fb-f00fdc7d7d75" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Liabilities"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_ca1afa13-5647-46cc-9d57-18183efa6ec6" xlink:to="loc_us-gaap_Liabilities_f34a1d51-311f-48e7-a5fb-f00fdc7d7d75" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_76884106-46ab-4cc3-9982-d3556538ebc2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_ca1afa13-5647-46cc-9d57-18183efa6ec6" xlink:to="loc_us-gaap_CommitmentsAndContingencies_76884106-46ab-4cc3-9982-d3556538ebc2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityAbstract_cc200ad8-aa5f-4296-99ad-4c957d29dc2e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquityAbstract"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_ca1afa13-5647-46cc-9d57-18183efa6ec6" xlink:to="loc_us-gaap_StockholdersEquityAbstract_cc200ad8-aa5f-4296-99ad-4c957d29dc2e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockValue_a62dbe68-620c-4b5a-8c8c-210edb0dcac3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PreferredStockValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_cc200ad8-aa5f-4296-99ad-4c957d29dc2e" xlink:to="loc_us-gaap_PreferredStockValue_a62dbe68-620c-4b5a-8c8c-210edb0dcac3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_ed4ededc-2dbd-4fad-a13a-16f39a4a9a63" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_cc200ad8-aa5f-4296-99ad-4c957d29dc2e" xlink:to="loc_us-gaap_CommonStockValue_ed4ededc-2dbd-4fad-a13a-16f39a4a9a63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_1c333e28-baba-4cdf-9456-2cc93d1c6b5a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_cc200ad8-aa5f-4296-99ad-4c957d29dc2e" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_1c333e28-baba-4cdf-9456-2cc93d1c6b5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_f77c8fcc-3537-478d-9584-16f98fa30f70" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdditionalPaidInCapitalCommonStock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_cc200ad8-aa5f-4296-99ad-4c957d29dc2e" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_f77c8fcc-3537-478d-9584-16f98fa30f70" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_8d1c196d-5194-41be-89f8-e8b8210fa937" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_cc200ad8-aa5f-4296-99ad-4c957d29dc2e" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_8d1c196d-5194-41be-89f8-e8b8210fa937" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_5f60d471-60de-4fee-a43c-0f1674aa6b0b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_cc200ad8-aa5f-4296-99ad-4c957d29dc2e" xlink:to="loc_us-gaap_StockholdersEquity_5f60d471-60de-4fee-a43c-0f1674aa6b0b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_16b02662-21dd-4811-8781-8d3268aacf24" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_ca1afa13-5647-46cc-9d57-18183efa6ec6" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_16b02662-21dd-4811-8781-8d3268aacf24" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="simple" xlink:href="dare-20210930.xsd#CondensedConsolidatedBalanceSheetsParenthetical"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_55f1d372-52db-4d0a-bc0b-c6b8fad447fe" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_b706d0c8-c8c3-4f24-a4d6-1b89972a6290" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PreferredStockParOrStatedValuePerShare"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_55f1d372-52db-4d0a-bc0b-c6b8fad447fe" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_b706d0c8-c8c3-4f24-a4d6-1b89972a6290" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_a3b3c82d-039f-446d-8cf5-a829a2e3432f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PreferredStockSharesAuthorized"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_55f1d372-52db-4d0a-bc0b-c6b8fad447fe" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_a3b3c82d-039f-446d-8cf5-a829a2e3432f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesIssued_26d9b8d9-3c36-47eb-8c1b-be479b368c5a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PreferredStockSharesIssued"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_55f1d372-52db-4d0a-bc0b-c6b8fad447fe" xlink:to="loc_us-gaap_PreferredStockSharesIssued_26d9b8d9-3c36-47eb-8c1b-be479b368c5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_e045a258-0b7d-47b5-9f1a-eb86f9f37329" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PreferredStockSharesOutstanding"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_55f1d372-52db-4d0a-bc0b-c6b8fad447fe" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_e045a258-0b7d-47b5-9f1a-eb86f9f37329" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_d8339900-8577-4134-a656-274cda307885" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_55f1d372-52db-4d0a-bc0b-c6b8fad447fe" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_d8339900-8577-4134-a656-274cda307885" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_541d49ab-7785-4cb8-84d0-8aa6466cdae0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_55f1d372-52db-4d0a-bc0b-c6b8fad447fe" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_541d49ab-7785-4cb8-84d0-8aa6466cdae0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_17850300-d306-43e6-814d-9e481d0cf675" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesIssued"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_55f1d372-52db-4d0a-bc0b-c6b8fad447fe" xlink:to="loc_us-gaap_CommonStockSharesIssued_17850300-d306-43e6-814d-9e481d0cf675" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_f29bd05d-a7d7-4d5c-b653-147863a71281" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_55f1d372-52db-4d0a-bc0b-c6b8fad447fe" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_f29bd05d-a7d7-4d5c-b653-147863a71281" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/CondensedConsolidatedStatementsofOperationsandComprehensiveLoss" xlink:type="simple" xlink:href="dare-20210930.xsd#CondensedConsolidatedStatementsofOperationsandComprehensiveLoss"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/CondensedConsolidatedStatementsofOperationsandComprehensiveLoss" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementAbstract_f1178313-cf90-46a4-aa74-30ccc233806b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpensesAbstract_15f3e31f-e69f-4ab2-ada4-2918b8c68a8d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingExpensesAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_f1178313-cf90-46a4-aa74-30ccc233806b" xlink:to="loc_us-gaap_OperatingExpensesAbstract_15f3e31f-e69f-4ab2-ada4-2918b8c68a8d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_c7e92afc-b11b-4af3-9b0d-2c6b2eb46891" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GeneralAndAdministrativeExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_15f3e31f-e69f-4ab2-ada4-2918b8c68a8d" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_c7e92afc-b11b-4af3-9b0d-2c6b2eb46891" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_4134505c-9eea-4441-b552-4e7f1621123f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_15f3e31f-e69f-4ab2-ada4-2918b8c68a8d" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_4134505c-9eea-4441-b552-4e7f1621123f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseFee_b453eef8-573c-448f-bd5d-8da40c9c40e7" xlink:href="dare-20210930.xsd#dare_LicenseFee"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_15f3e31f-e69f-4ab2-ada4-2918b8c68a8d" xlink:to="loc_dare_LicenseFee_b453eef8-573c-448f-bd5d-8da40c9c40e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_291d01b4-fd03-464f-a148-5ac6bda53c74" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingExpenses"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_15f3e31f-e69f-4ab2-ada4-2918b8c68a8d" xlink:to="loc_us-gaap_OperatingExpenses_291d01b4-fd03-464f-a148-5ac6bda53c74" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_d8f957c1-24b1-43e1-b925-b3472e0faa32" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_f1178313-cf90-46a4-aa74-30ccc233806b" xlink:to="loc_us-gaap_OperatingIncomeLoss_d8f957c1-24b1-43e1-b925-b3472e0faa32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_c4014593-0ae9-45b3-b7e4-2764bf6a621c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_f1178313-cf90-46a4-aa74-30ccc233806b" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_c4014593-0ae9-45b3-b7e4-2764bf6a621c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_d6abcb07-d8b6-4ef9-9383-4bf28f55f20f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_f1178313-cf90-46a4-aa74-30ccc233806b" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_d6abcb07-d8b6-4ef9-9383-4bf28f55f20f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_2bdad586-b29d-4f47-8553-76ec82ac8c41" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_f1178313-cf90-46a4-aa74-30ccc233806b" xlink:to="loc_us-gaap_NetIncomeLoss_2bdad586-b29d-4f47-8553-76ec82ac8c41" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_58defb3a-5acb-4a6f-98d2-7b88fc50ea40" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_f1178313-cf90-46a4-aa74-30ccc233806b" xlink:to="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_58defb3a-5acb-4a6f-98d2-7b88fc50ea40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_80cf90c3-3f1b-4900-8c70-902456d33fb1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_f1178313-cf90-46a4-aa74-30ccc233806b" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_80cf90c3-3f1b-4900-8c70-902456d33fb1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_3531fe9c-c65a-47c3-af5e-ac03a1943db1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_f1178313-cf90-46a4-aa74-30ccc233806b" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_3531fe9c-c65a-47c3-af5e-ac03a1943db1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_016050d3-8e7a-4725-b53c-cf9e9a3268e7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_f1178313-cf90-46a4-aa74-30ccc233806b" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_016050d3-8e7a-4725-b53c-cf9e9a3268e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_f52474eb-4246-4a15-a547-1df1c8a42b85" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_f1178313-cf90-46a4-aa74-30ccc233806b" xlink:to="loc_us-gaap_EarningsPerShareBasic_f52474eb-4246-4a15-a547-1df1c8a42b85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_3b34037e-be4b-449d-997d-57f2c4293ec9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_f1178313-cf90-46a4-aa74-30ccc233806b" xlink:to="loc_us-gaap_EarningsPerShareDiluted_3b34037e-be4b-449d-997d-57f2c4293ec9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_99c4e08a-8950-407f-a6e4-faca084d7ae2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_f1178313-cf90-46a4-aa74-30ccc233806b" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_99c4e08a-8950-407f-a6e4-faca084d7ae2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_e810ead5-6b6a-4d6e-bcce-e5de1458e911" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_99c4e08a-8950-407f-a6e4-faca084d7ae2" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_e810ead5-6b6a-4d6e-bcce-e5de1458e911" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_3a5a0b8d-2b6c-4fc3-a6ca-3ccb1d466722" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_99c4e08a-8950-407f-a6e4-faca084d7ae2" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_3a5a0b8d-2b6c-4fc3-a6ca-3ccb1d466722" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/CondensedConsolidatedStatementsofStockholdersEquityDeficit" xlink:type="simple" xlink:href="dare-20210930.xsd#CondensedConsolidatedStatementsofStockholdersEquityDeficit"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/CondensedConsolidatedStatementsofStockholdersEquityDeficit" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_b2d4e792-7145-4f80-b380-945a5b2fedee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_64042f34-5999-4aa0-ad49-10b2f231b260" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_b2d4e792-7145-4f80-b380-945a5b2fedee" xlink:to="loc_us-gaap_StatementTable_64042f34-5999-4aa0-ad49-10b2f231b260" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_99016a84-362b-4cce-887e-1db53b14bcdd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_64042f34-5999-4aa0-ad49-10b2f231b260" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_99016a84-362b-4cce-887e-1db53b14bcdd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_95a8d19f-2471-414a-a62b-913732af0c7b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_99016a84-362b-4cce-887e-1db53b14bcdd" xlink:to="loc_us-gaap_EquityComponentDomain_95a8d19f-2471-414a-a62b-913732af0c7b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_be180c3d-d57f-41f7-a73d-7557170128f4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_95a8d19f-2471-414a-a62b-913732af0c7b" xlink:to="loc_us-gaap_CommonStockMember_be180c3d-d57f-41f7-a73d-7557170128f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_1245259d-ee1d-4df1-a1b0-bbc3f0820027" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_95a8d19f-2471-414a-a62b-913732af0c7b" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_1245259d-ee1d-4df1-a1b0-bbc3f0820027" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_93819b8a-1d84-43e5-812d-99256a7ce821" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_95a8d19f-2471-414a-a62b-913732af0c7b" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_93819b8a-1d84-43e5-812d-99256a7ce821" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_b587816c-78d4-43e4-a224-475b64e92570" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_95a8d19f-2471-414a-a62b-913732af0c7b" xlink:to="loc_us-gaap_RetainedEarningsMember_b587816c-78d4-43e4-a224-475b64e92570" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_c92d8c86-b1b1-4aca-ab73-50d56462e75f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_64042f34-5999-4aa0-ad49-10b2f231b260" xlink:to="loc_us-gaap_StatementLineItems_c92d8c86-b1b1-4aca-ab73-50d56462e75f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_c92d8c86-b1b1-4aca-ab73-50d56462e75f" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_26bfdcee-4941-4362-bb84-d2a6657f2397" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SharesOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_us-gaap_SharesOutstanding_26bfdcee-4941-4362-bb84-d2a6657f2397" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_46c6c6ec-ea53-4a34-8ec7-c3a057353bd9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_us-gaap_StockholdersEquity_46c6c6ec-ea53-4a34-8ec7-c3a057353bd9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_7d94197a-bb61-482f-8153-3de692198e32" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_7d94197a-bb61-482f-8153-3de692198e32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_1b4c6603-0cab-4343-842e-7b13df4fabf3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_1b4c6603-0cab-4343-842e-7b13df4fabf3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_83add8ed-a599-43b9-b5bb-50d476951295" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_83add8ed-a599-43b9-b5bb-50d476951295" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_StockIssuedDuringPeriodSharesConsiderationForCommitmentToPurchaseShares_17fac73b-4885-4f96-839e-bb8da77e00bf" xlink:href="dare-20210930.xsd#dare_StockIssuedDuringPeriodSharesConsiderationForCommitmentToPurchaseShares"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_dare_StockIssuedDuringPeriodSharesConsiderationForCommitmentToPurchaseShares_17fac73b-4885-4f96-839e-bb8da77e00bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_StockIssuedDuringPeriodValueConsiderationForCommitmentToPurchaseShares_a07eaafe-4dae-44f4-9fed-47db78e39963" xlink:href="dare-20210930.xsd#dare_StockIssuedDuringPeriodValueConsiderationForCommitmentToPurchaseShares"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_dare_StockIssuedDuringPeriodValueConsiderationForCommitmentToPurchaseShares_a07eaafe-4dae-44f4-9fed-47db78e39963" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AdjustmentsToAdditionalPaidInCapitalCommonStockAndWarrantsIssuedShares_c4348869-c61f-4bb1-bbf3-4e3fc04ef9ce" xlink:href="dare-20210930.xsd#dare_AdjustmentsToAdditionalPaidInCapitalCommonStockAndWarrantsIssuedShares"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_dare_AdjustmentsToAdditionalPaidInCapitalCommonStockAndWarrantsIssuedShares_c4348869-c61f-4bb1-bbf3-4e3fc04ef9ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalWarrantIssued_feb4d531-f7c4-422c-b0e3-e60ed177acff" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalWarrantIssued"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalWarrantIssued_feb4d531-f7c4-422c-b0e3-e60ed177acff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_StockIssuedDuringPeriodSharesMilestonePayment_b15d3371-f215-477c-bd87-3d74ff62da77" xlink:href="dare-20210930.xsd#dare_StockIssuedDuringPeriodSharesMilestonePayment"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_dare_StockIssuedDuringPeriodSharesMilestonePayment_b15d3371-f215-477c-bd87-3d74ff62da77" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_StockIssuedDuringPeriodValueMilestonePayment_1c31b975-5357-40c2-bc79-bc5dd9d3ad69" xlink:href="dare-20210930.xsd#dare_StockIssuedDuringPeriodValueMilestonePayment"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_dare_StockIssuedDuringPeriodValueMilestonePayment_1c31b975-5357-40c2-bc79-bc5dd9d3ad69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_d39d0fd2-4d42-4620-ab68-e83ccd2f5478" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_d39d0fd2-4d42-4620-ab68-e83ccd2f5478" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_8121e48f-2230-4eea-b662-cf75d9d2ca8a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_8121e48f-2230-4eea-b662-cf75d9d2ca8a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_96819ba8-04ea-4665-a9ac-8477dfda96d0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_96819ba8-04ea-4665-a9ac-8477dfda96d0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_fec6a8f1-f30f-4d06-bf32-caa986d7949f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_us-gaap_NetIncomeLoss_fec6a8f1-f30f-4d06-bf32-caa986d7949f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_ca1f8a39-981a-4499-80c9-8aaed3c4b4cd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_ca1f8a39-981a-4499-80c9-8aaed3c4b4cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_ae90b9bc-46b2-4f0c-a9b0-ccb81bfa2c5b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SharesOutstanding"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_us-gaap_SharesOutstanding_ae90b9bc-46b2-4f0c-a9b0-ccb81bfa2c5b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_cd8ccf9f-e081-4206-a5fc-246c2d731b84" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_abed0dfc-86e2-43d2-a175-bc1dd20c2c83" xlink:to="loc_us-gaap_StockholdersEquity_cd8ccf9f-e081-4206-a5fc-246c2d731b84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="dare-20210930.xsd#CondensedConsolidatedStatementsofCashFlows"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_86d639bb-0802-48e7-8a1d-d136e74c1261" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_062bbbfe-7ff5-4784-8cba-7cb4ce5232d7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_86d639bb-0802-48e7-8a1d-d136e74c1261" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_062bbbfe-7ff5-4784-8cba-7cb4ce5232d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_9ed5c526-3a61-4efd-a207-e26c5aa490b7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_062bbbfe-7ff5-4784-8cba-7cb4ce5232d7" xlink:to="loc_us-gaap_NetIncomeLoss_9ed5c526-3a61-4efd-a207-e26c5aa490b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_22bd6635-1e1f-4d40-b06d-748ef193d7b8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_062bbbfe-7ff5-4784-8cba-7cb4ce5232d7" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_22bd6635-1e1f-4d40-b06d-748ef193d7b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Depreciation_76144702-3b40-47c7-ba0e-b30590bf2bea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Depreciation"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_22bd6635-1e1f-4d40-b06d-748ef193d7b8" xlink:to="loc_us-gaap_Depreciation_76144702-3b40-47c7-ba0e-b30590bf2bea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_c8f6533c-bffe-43ca-85df-3b35384417ee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensation"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_22bd6635-1e1f-4d40-b06d-748ef193d7b8" xlink:to="loc_us-gaap_ShareBasedCompensation_c8f6533c-bffe-43ca-85df-3b35384417ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_NonCashLeaseExpense_b2c544fa-76a3-4ba1-967e-6015fa1cdc65" xlink:href="dare-20210930.xsd#dare_NonCashLeaseExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_22bd6635-1e1f-4d40-b06d-748ef193d7b8" xlink:to="loc_dare_NonCashLeaseExpense_b2c544fa-76a3-4ba1-967e-6015fa1cdc65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_f97d3ebc-a2fd-4f13-8f26-b6611e76b31b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_22bd6635-1e1f-4d40-b06d-748ef193d7b8" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_f97d3ebc-a2fd-4f13-8f26-b6611e76b31b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_c20946b9-5190-4cfc-9f21-496b4027efaa" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_22bd6635-1e1f-4d40-b06d-748ef193d7b8" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_c20946b9-5190-4cfc-9f21-496b4027efaa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_7a7e5dff-3f7b-4eac-b349-065b6112e601" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_22bd6635-1e1f-4d40-b06d-748ef193d7b8" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_7a7e5dff-3f7b-4eac-b349-065b6112e601" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherReceivables_9b210ae2-85a9-4135-9617-f43e55a9ca23" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOtherReceivables"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_7a7e5dff-3f7b-4eac-b349-065b6112e601" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherReceivables_9b210ae2-85a9-4135-9617-f43e55a9ca23" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidExpense_cdf21c7d-0168-4e1e-aebc-29a6ad47b66a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_7a7e5dff-3f7b-4eac-b349-065b6112e601" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidExpense_cdf21c7d-0168-4e1e-aebc-29a6ad47b66a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_IncreaseDecreaseInOtherNonCurrentAssetsAndDeferredCharges_ac466bd2-7ca2-4022-9739-04b91bea38e5" xlink:href="dare-20210930.xsd#dare_IncreaseDecreaseInOtherNonCurrentAssetsAndDeferredCharges"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_7a7e5dff-3f7b-4eac-b349-065b6112e601" xlink:to="loc_dare_IncreaseDecreaseInOtherNonCurrentAssetsAndDeferredCharges_ac466bd2-7ca2-4022-9739-04b91bea38e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_b62e2aaa-61c7-4480-abd2-231b5ec38dc5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_7a7e5dff-3f7b-4eac-b349-065b6112e601" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_b62e2aaa-61c7-4480-abd2-231b5ec38dc5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_eedfd063-d4a9-4f68-abb2-83559a4ce86d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_7a7e5dff-3f7b-4eac-b349-065b6112e601" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_eedfd063-d4a9-4f68-abb2-83559a4ce86d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_IncreaseDecreaseInDeferredGrantFunding_e3611265-fe97-4dcb-bd4d-01a6c12bf6a4" xlink:href="dare-20210930.xsd#dare_IncreaseDecreaseInDeferredGrantFunding"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_7a7e5dff-3f7b-4eac-b349-065b6112e601" xlink:to="loc_dare_IncreaseDecreaseInDeferredGrantFunding_e3611265-fe97-4dcb-bd4d-01a6c12bf6a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_d57e3809-070f-4a7e-a33b-de4f1fb69098" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInContractWithCustomerLiability"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_7a7e5dff-3f7b-4eac-b349-065b6112e601" xlink:to="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_d57e3809-070f-4a7e-a33b-de4f1fb69098" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_9ad5dfcc-67ad-4f12-93fa-15e1817e499c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_062bbbfe-7ff5-4784-8cba-7cb4ce5232d7" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_9ad5dfcc-67ad-4f12-93fa-15e1817e499c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_cdc51d34-e342-4430-bd3b-a95a90724342" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_86d639bb-0802-48e7-8a1d-d136e74c1261" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_cdc51d34-e342-4430-bd3b-a95a90724342" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_00cb1509-759e-40d9-90b7-edcf59845405" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_cdc51d34-e342-4430-bd3b-a95a90724342" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_00cb1509-759e-40d9-90b7-edcf59845405" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_62a281bb-6749-4273-9c7d-f2fa10d05fe0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_cdc51d34-e342-4430-bd3b-a95a90724342" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_62a281bb-6749-4273-9c7d-f2fa10d05fe0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50cdc0f2-6d58-42ac-bb8f-fdcaeb88e527" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_86d639bb-0802-48e7-8a1d-d136e74c1261" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50cdc0f2-6d58-42ac-bb8f-fdcaeb88e527" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_NetProceedsFromIssuanceOfCommonStockAndWarrants_f5e64eb5-edac-415f-861d-924269b75f33" xlink:href="dare-20210930.xsd#dare_NetProceedsFromIssuanceOfCommonStockAndWarrants"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50cdc0f2-6d58-42ac-bb8f-fdcaeb88e527" xlink:to="loc_dare_NetProceedsFromIssuanceOfCommonStockAndWarrants_f5e64eb5-edac-415f-861d-924269b75f33" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ProceedsFromIssuanceOfCommonStockAndWarrants_9a4e28c3-62a3-4962-b823-0908c3ecc63d" xlink:href="dare-20210930.xsd#dare_ProceedsFromIssuanceOfCommonStockAndWarrants"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50cdc0f2-6d58-42ac-bb8f-fdcaeb88e527" xlink:to="loc_dare_ProceedsFromIssuanceOfCommonStockAndWarrants_9a4e28c3-62a3-4962-b823-0908c3ecc63d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOrSaleOfEquity_18621dba-c358-44c4-a7c1-9c06b72c9f47" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromIssuanceOrSaleOfEquity"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50cdc0f2-6d58-42ac-bb8f-fdcaeb88e527" xlink:to="loc_us-gaap_ProceedsFromIssuanceOrSaleOfEquity_18621dba-c358-44c4-a7c1-9c06b72c9f47" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromNotesPayable_dd149b3c-5f64-4b13-8fb0-c6b0448bb718" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromNotesPayable"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50cdc0f2-6d58-42ac-bb8f-fdcaeb88e527" xlink:to="loc_us-gaap_ProceedsFromNotesPayable_dd149b3c-5f64-4b13-8fb0-c6b0448bb718" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_0e4d65a6-ae6f-4952-8c55-ba285a87e3f6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50cdc0f2-6d58-42ac-bb8f-fdcaeb88e527" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_0e4d65a6-ae6f-4952-8c55-ba285a87e3f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_9300df68-ab99-4425-8c64-b1a5bc49da8c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_86d639bb-0802-48e7-8a1d-d136e74c1261" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_9300df68-ab99-4425-8c64-b1a5bc49da8c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_b548fac7-7307-4440-8b21-62ce5dc2bf53" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_86d639bb-0802-48e7-8a1d-d136e74c1261" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_b548fac7-7307-4440-8b21-62ce5dc2bf53" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_635c595f-9011-439c-a8b4-2fef4f99323d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_86d639bb-0802-48e7-8a1d-d136e74c1261" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_635c595f-9011-439c-a8b4-2fef4f99323d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_46a667f3-ebd9-4b1c-b6c7-fbc5166d7220" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_86d639bb-0802-48e7-8a1d-d136e74c1261" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_46a667f3-ebd9-4b1c-b6c7-fbc5166d7220" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_1e696652-fa93-47a8-8102-42224b1104ff" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_86d639bb-0802-48e7-8a1d-d136e74c1261" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_1e696652-fa93-47a8-8102-42224b1104ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_fe7d8d79-277d-4cd4-a21d-08410644a15f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_1e696652-fa93-47a8-8102-42224b1104ff" xlink:to="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_fe7d8d79-277d-4cd4-a21d-08410644a15f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_NoncashOrPartNoncashAcquisitionCommonStockIssuedForSettlementOfContingentConsiderationLiability_4862f5f4-f4aa-49d3-b963-d7a445f1a64e" xlink:href="dare-20210930.xsd#dare_NoncashOrPartNoncashAcquisitionCommonStockIssuedForSettlementOfContingentConsiderationLiability"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_1e696652-fa93-47a8-8102-42224b1104ff" xlink:to="loc_dare_NoncashOrPartNoncashAcquisitionCommonStockIssuedForSettlementOfContingentConsiderationLiability_4862f5f4-f4aa-49d3-b963-d7a445f1a64e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MilestonePaymentsContingentAmount_290db404-f4dd-4980-acdc-43739986df37" xlink:href="dare-20210930.xsd#dare_MilestonePaymentsContingentAmount"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_1e696652-fa93-47a8-8102-42224b1104ff" xlink:to="loc_dare_MilestonePaymentsContingentAmount_290db404-f4dd-4980-acdc-43739986df37" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_IssuanceCostOnEquityPaidInCommonStock_95dc1c9c-3abf-4198-93f3-ede2e97bb503" xlink:href="dare-20210930.xsd#dare_IssuanceCostOnEquityPaidInCommonStock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_1e696652-fa93-47a8-8102-42224b1104ff" xlink:to="loc_dare_IssuanceCostOnEquityPaidInCommonStock_95dc1c9c-3abf-4198-93f3-ede2e97bb503" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_97c1b56f-dd96-4d4b-8508-cba9c7c5ccf6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_1e696652-fa93-47a8-8102-42224b1104ff" xlink:to="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_97c1b56f-dd96-4d4b-8508-cba9c7c5ccf6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/OrganizationandDescriptionofBusiness" xlink:type="simple" xlink:href="dare-20210930.xsd#OrganizationandDescriptionofBusiness"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/OrganizationandDescriptionofBusiness" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_db2d3437-dce5-428c-b0b7-f3d88d72e619" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_b12a92da-f050-45ef-9b58-6639433061e9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_db2d3437-dce5-428c-b0b7-f3d88d72e619" xlink:to="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_b12a92da-f050-45ef-9b58-6639433061e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/OrganizationandDescriptionofBusinessAdditionalInformationDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#OrganizationandDescriptionofBusinessAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/OrganizationandDescriptionofBusinessAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5eba5c77-7937-4d65-8082-cf7365997745" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfOperatingSegments_b9bad9f0-66a2-48a9-9575-5be78840d85b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NumberOfOperatingSegments"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5eba5c77-7937-4d65-8082-cf7365997745" xlink:to="loc_us-gaap_NumberOfOperatingSegments_b9bad9f0-66a2-48a9-9575-5be78840d85b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_65d339eb-170d-49be-8c3b-0640347ce629" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5eba5c77-7937-4d65-8082-cf7365997745" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_65d339eb-170d-49be-8c3b-0640347ce629" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_a8eb09ef-afa9-4f76-9608-ed4ed9e428d7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5eba5c77-7937-4d65-8082-cf7365997745" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_a8eb09ef-afa9-4f76-9608-ed4ed9e428d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_WorkingCapitalIncreaseDeficit_08012701-0c91-43ed-ae54-9a0774e61b2b" xlink:href="dare-20210930.xsd#dare_WorkingCapitalIncreaseDeficit"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5eba5c77-7937-4d65-8082-cf7365997745" xlink:to="loc_dare_WorkingCapitalIncreaseDeficit_08012701-0c91-43ed-ae54-9a0774e61b2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_95d9d7ef-b6e1-428f-9f00-b60ac7a2f0b5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5eba5c77-7937-4d65-8082-cf7365997745" xlink:to="loc_us-gaap_NetIncomeLoss_95d9d7ef-b6e1-428f-9f00-b60ac7a2f0b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations_f8f7295d-4771-4f9d-891e-ebdd2e110cf2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5eba5c77-7937-4d65-8082-cf7365997745" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations_f8f7295d-4771-4f9d-891e-ebdd2e110cf2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PeriodofInsufficientCashandLiquidityRequirements_32950293-d19b-4207-9d85-b68302da42fa" xlink:href="dare-20210930.xsd#dare_PeriodofInsufficientCashandLiquidityRequirements"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5eba5c77-7937-4d65-8082-cf7365997745" xlink:to="loc_dare_PeriodofInsufficientCashandLiquidityRequirements_32950293-d19b-4207-9d85-b68302da42fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/SummaryofSignificantAccountingPolicies" xlink:type="simple" xlink:href="dare-20210930.xsd#SummaryofSignificantAccountingPolicies"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/SummaryofSignificantAccountingPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_b0b579e1-a76d-44aa-9cb3-3363be32579c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock_3198c4f6-79dd-48ec-a599-ff208a2314b4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SignificantAccountingPoliciesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_b0b579e1-a76d-44aa-9cb3-3363be32579c" xlink:to="loc_us-gaap_SignificantAccountingPoliciesTextBlock_3198c4f6-79dd-48ec-a599-ff208a2314b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/SummaryofSignificantAccountingPoliciesPolicies" xlink:type="simple" xlink:href="dare-20210930.xsd#SummaryofSignificantAccountingPoliciesPolicies"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/SummaryofSignificantAccountingPoliciesPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_47021b4d-5c21-4465-9806-8295b5292b75" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_7db61174-e246-4f3c-b04a-c9870f42a6e3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_47021b4d-5c21-4465-9806-8295b5292b75" xlink:to="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_7db61174-e246-4f3c-b04a-c9870f42a6e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeasesPolicyTextBlock_9bb844e7-3b07-456b-a059-4e70acbcb66b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeLeasesPolicyTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_47021b4d-5c21-4465-9806-8295b5292b75" xlink:to="loc_us-gaap_LesseeLeasesPolicyTextBlock_9bb844e7-3b07-456b-a059-4e70acbcb66b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_2d0a53dd-fa5f-4ddf-a9d7-cb7aaeb6270a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementPolicyPolicyTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_47021b4d-5c21-4465-9806-8295b5292b75" xlink:to="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_2d0a53dd-fa5f-4ddf-a9d7-cb7aaeb6270a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_95487bb6-4957-4068-9ee5-9cd3c32fb5bf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_47021b4d-5c21-4465-9806-8295b5292b75" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_95487bb6-4957-4068-9ee5-9cd3c32fb5bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/SummaryofSignificantAccountingPoliciesTables" xlink:type="simple" xlink:href="dare-20210930.xsd#SummaryofSignificantAccountingPoliciesTables"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/SummaryofSignificantAccountingPoliciesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_99faa4f5-d721-4e98-ba17-b3babb6070f9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisTextBlock_c7d74bba-e27e-49bd-9520-8ec51553fcc6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_99faa4f5-d721-4e98-ba17-b3babb6070f9" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisTextBlock_c7d74bba-e27e-49bd-9520-8ec51553fcc6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/SummaryofSignificantAccountingPoliciesFinancialAssetsandLiabilitiesRemeasuredonaRecurringBasisDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#SummaryofSignificantAccountingPoliciesFinancialAssetsandLiabilitiesRemeasuredonaRecurringBasisDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/SummaryofSignificantAccountingPoliciesFinancialAssetsandLiabilitiesRemeasuredonaRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_3214a50c-7013-4188-b6dd-e2e2a6283f57" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_5e5f6b58-3000-4b2b-a3b3-0aabc0d66e4d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_3214a50c-7013-4188-b6dd-e2e2a6283f57" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_5e5f6b58-3000-4b2b-a3b3-0aabc0d66e4d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_1b876531-d89b-4db8-9e7f-ab529e01286a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_5e5f6b58-3000-4b2b-a3b3-0aabc0d66e4d" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_1b876531-d89b-4db8-9e7f-ab529e01286a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_7029a021-05fe-4e97-b81d-8bb677723133" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_1b876531-d89b-4db8-9e7f-ab529e01286a" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_7029a021-05fe-4e97-b81d-8bb677723133" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_c26e2013-97c2-4b2b-ad77-7a87471ac454" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_7029a021-05fe-4e97-b81d-8bb677723133" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_c26e2013-97c2-4b2b-ad77-7a87471ac454" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_702cb88e-f6ed-4aaa-b4f5-bec634fffe04" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_5e5f6b58-3000-4b2b-a3b3-0aabc0d66e4d" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_702cb88e-f6ed-4aaa-b4f5-bec634fffe04" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1c42e968-5d20-4fd4-a8f3-9644053fface" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_702cb88e-f6ed-4aaa-b4f5-bec634fffe04" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1c42e968-5d20-4fd4-a8f3-9644053fface" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_47360ce0-48ec-4c30-aded-1acba8a13bec" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1c42e968-5d20-4fd4-a8f3-9644053fface" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_47360ce0-48ec-4c30-aded-1acba8a13bec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_663e6a64-dcf7-44b4-b6c9-7d19cb39b2ed" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel2Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1c42e968-5d20-4fd4-a8f3-9644053fface" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_663e6a64-dcf7-44b4-b6c9-7d19cb39b2ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_4095e40b-9bd6-4997-971e-77d0514cb28a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel3Member"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_1c42e968-5d20-4fd4-a8f3-9644053fface" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_4095e40b-9bd6-4997-971e-77d0514cb28a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_f1d2d871-0409-4f35-be56-59ec07cb8f4a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_5e5f6b58-3000-4b2b-a3b3-0aabc0d66e4d" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_f1d2d871-0409-4f35-be56-59ec07cb8f4a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_f13e69d5-5c06-4325-8a66-a83236e404a8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_f1d2d871-0409-4f35-be56-59ec07cb8f4a" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_f13e69d5-5c06-4325-8a66-a83236e404a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetAcquisitionContingentConsiderationLiabilityNoncurrent_f6635b44-fc25-41fa-89a2-d35c50745ba9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetAcquisitionContingentConsiderationLiabilityNoncurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_f1d2d871-0409-4f35-be56-59ec07cb8f4a" xlink:to="loc_us-gaap_AssetAcquisitionContingentConsiderationLiabilityNoncurrent_f6635b44-fc25-41fa-89a2-d35c50745ba9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/SummaryofSignificantAccountingPoliciesAdditionalInformationDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#SummaryofSignificantAccountingPoliciesAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/SummaryofSignificantAccountingPoliciesAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_1fcddabd-7636-47dc-aeb2-85d2065f6d0a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_SignificantAccountingPoliciesTable_b793993f-2a9d-407c-824c-7db633686541" xlink:href="dare-20210930.xsd#dare_SignificantAccountingPoliciesTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_1fcddabd-7636-47dc-aeb2-85d2065f6d0a" xlink:to="loc_dare_SignificantAccountingPoliciesTable_b793993f-2a9d-407c-824c-7db633686541" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis_e345aabf-d07b-4a2f-aff6-b9daf689a5bc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TypeOfArrangementAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesTable_b793993f-2a9d-407c-824c-7db633686541" xlink:to="loc_us-gaap_TypeOfArrangementAxis_e345aabf-d07b-4a2f-aff6-b9daf689a5bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_3a4434bb-f449-4aa1-a310-5310fb042602" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfArrangementAxis_e345aabf-d07b-4a2f-aff6-b9daf689a5bc" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_3a4434bb-f449-4aa1-a310-5310fb042602" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_BayerHealthcareLicenseAgreementMember_9425e2ac-1e1b-4723-98b2-1f31b4e664dd" xlink:href="dare-20210930.xsd#dare_BayerHealthcareLicenseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_3a4434bb-f449-4aa1-a310-5310fb042602" xlink:to="loc_dare_BayerHealthcareLicenseAgreementMember_9425e2ac-1e1b-4723-98b2-1f31b4e664dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_SignificantAccountingPoliciesLineItems_82f500fc-b0ec-4caa-95c7-e1c3077f8ce2" xlink:href="dare-20210930.xsd#dare_SignificantAccountingPoliciesLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesTable_b793993f-2a9d-407c-824c-7db633686541" xlink:to="loc_dare_SignificantAccountingPoliciesLineItems_82f500fc-b0ec-4caa-95c7-e1c3077f8ce2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UpfrontLicenseFeePaid_69a7e047-881d-45d3-8f59-61fbb5cb920d" xlink:href="dare-20210930.xsd#dare_UpfrontLicenseFeePaid"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_82f500fc-b0ec-4caa-95c7-e1c3077f8ce2" xlink:to="loc_dare_UpfrontLicenseFeePaid_69a7e047-881d-45d3-8f59-61fbb5cb920d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_eb4226ea-affe-43c5-8127-ab186f605838" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_82f500fc-b0ec-4caa-95c7-e1c3077f8ce2" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_eb4226ea-affe-43c5-8127-ab186f605838" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_NumberOfSignificantPerformanceObligations_b8daa8a8-7bd6-443d-92b6-ede0cb4b2b6c" xlink:href="dare-20210930.xsd#dare_NumberOfSignificantPerformanceObligations"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_82f500fc-b0ec-4caa-95c7-e1c3077f8ce2" xlink:to="loc_dare_NumberOfSignificantPerformanceObligations_b8daa8a8-7bd6-443d-92b6-ede0cb4b2b6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MilestonePaymentsContingentAmount_659b5860-39e6-46aa-84e3-164c17e32878" xlink:href="dare-20210930.xsd#dare_MilestonePaymentsContingentAmount"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_82f500fc-b0ec-4caa-95c7-e1c3077f8ce2" xlink:to="loc_dare_MilestonePaymentsContingentAmount_659b5860-39e6-46aa-84e3-164c17e32878" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/LicenseandCollaborationAgreements" xlink:type="simple" xlink:href="dare-20210930.xsd#LicenseandCollaborationAgreements"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/LicenseandCollaborationAgreements" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_9d774910-3a23-4b5b-ac7a-d6efc14494d4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_8efdf30b-7f55-4a81-8c3e-be300b8a2e9e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CollaborativeArrangementDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_9d774910-3a23-4b5b-ac7a-d6efc14494d4" xlink:to="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_8efdf30b-7f55-4a81-8c3e-be300b8a2e9e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/LicenseandCollaborationAgreementsAdditionalInformationDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#LicenseandCollaborationAgreementsAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/LicenseandCollaborationAgreementsAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_00d51d09-9122-440e-9eac-6525017f5785" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_00d51d09-9122-440e-9eac-6525017f5785" xlink:to="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis_78f280e6-0765-4e46-aecf-d4b8d0e53c75" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TypeOfArrangementAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:to="loc_us-gaap_TypeOfArrangementAxis_78f280e6-0765-4e46-aecf-d4b8d0e53c75" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_5efb427c-fe75-415f-8f20-a5bc1117d5eb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfArrangementAxis_78f280e6-0765-4e46-aecf-d4b8d0e53c75" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_5efb427c-fe75-415f-8f20-a5bc1117d5eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_BayerHealthcareLicenseAgreementMember_9a4ef6d5-cf5b-4149-93d5-c3948610dc84" xlink:href="dare-20210930.xsd#dare_BayerHealthcareLicenseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_5efb427c-fe75-415f-8f20-a5bc1117d5eb" xlink:to="loc_dare_BayerHealthcareLicenseAgreementMember_9a4ef6d5-cf5b-4149-93d5-c3948610dc84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LicensingAgreementsMember_408aff1b-4308-4672-8c7b-13dc507190b8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LicensingAgreementsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_5efb427c-fe75-415f-8f20-a5bc1117d5eb" xlink:to="loc_us-gaap_LicensingAgreementsMember_408aff1b-4308-4672-8c7b-13dc507190b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AssignmentAgreementMember_29c6fcfe-c160-4ff4-be6e-92b2d86d8039" xlink:href="dare-20210930.xsd#dare_AssignmentAgreementMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_5efb427c-fe75-415f-8f20-a5bc1117d5eb" xlink:to="loc_dare_AssignmentAgreementMember_29c6fcfe-c160-4ff4-be6e-92b2d86d8039" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseAndCollaborationAgreementMember_acf34ced-a5a8-495d-98dc-39e7e15d1fca" xlink:href="dare-20210930.xsd#dare_LicenseAndCollaborationAgreementMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_5efb427c-fe75-415f-8f20-a5bc1117d5eb" xlink:to="loc_dare_LicenseAndCollaborationAgreementMember_acf34ced-a5a8-495d-98dc-39e7e15d1fca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_JuniperPharmaceuticalsInc.Member_0161c690-8c8e-4cf6-ba82-033ccc827c2b" xlink:href="dare-20210930.xsd#dare_JuniperPharmaceuticalsInc.Member"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_5efb427c-fe75-415f-8f20-a5bc1117d5eb" xlink:to="loc_dare_JuniperPharmaceuticalsInc.Member_0161c690-8c8e-4cf6-ba82-033ccc827c2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_DevelopmentAndOptionAgreementMember_78f06924-3331-4003-815e-5238183cb1bd" xlink:href="dare-20210930.xsd#dare_DevelopmentAndOptionAgreementMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_5efb427c-fe75-415f-8f20-a5bc1117d5eb" xlink:to="loc_dare_DevelopmentAndOptionAgreementMember_78f06924-3331-4003-815e-5238183cb1bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionAxis_e66e98fb-b76e-4d96-a27f-05b331e4400a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RelatedPartyTransactionAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:to="loc_us-gaap_RelatedPartyTransactionAxis_e66e98fb-b76e-4d96-a27f-05b331e4400a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionDomain_743873d8-3d84-4684-983a-ae03620c0840" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RelatedPartyTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionAxis_e66e98fb-b76e-4d96-a27f-05b331e4400a" xlink:to="loc_us-gaap_RelatedPartyTransactionDomain_743873d8-3d84-4684-983a-ae03620c0840" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponAchievingCertainDevelopmentMilestonesMember_e7549cf6-feaf-4d1d-952e-1828e8d24bb8" xlink:href="dare-20210930.xsd#dare_UponAchievingCertainDevelopmentMilestonesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_743873d8-3d84-4684-983a-ae03620c0840" xlink:to="loc_dare_UponAchievingCertainDevelopmentMilestonesMember_e7549cf6-feaf-4d1d-952e-1828e8d24bb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponAchievingCertainCommercialMilestonesMember_76e14d33-acca-41c6-aff3-874550e63c21" xlink:href="dare-20210930.xsd#dare_UponAchievingCertainCommercialMilestonesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_743873d8-3d84-4684-983a-ae03620c0840" xlink:to="loc_dare_UponAchievingCertainCommercialMilestonesMember_76e14d33-acca-41c6-aff3-874550e63c21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponAchievingCertainClinicalAndRegulatoryDevelopmentMilestonesMember_2af5011d-2bdb-45ec-a268-0e559bd18f9e" xlink:href="dare-20210930.xsd#dare_UponAchievingCertainClinicalAndRegulatoryDevelopmentMilestonesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_743873d8-3d84-4684-983a-ae03620c0840" xlink:to="loc_dare_UponAchievingCertainClinicalAndRegulatoryDevelopmentMilestonesMember_2af5011d-2bdb-45ec-a268-0e559bd18f9e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponSigningOfDevelopmentAndOptionAgreementMember_4f1660b9-a9ca-4a00-98f4-05c637d4976e" xlink:href="dare-20210930.xsd#dare_UponSigningOfDevelopmentAndOptionAgreementMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_743873d8-3d84-4684-983a-ae03620c0840" xlink:to="loc_dare_UponSigningOfDevelopmentAndOptionAgreementMember_4f1660b9-a9ca-4a00-98f4-05c637d4976e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponCompletionOfFiftyPercentDevelopmentNotLaterThanSixMonthsMember_967e2e03-7f1c-49da-95bd-fcd59838e6a9" xlink:href="dare-20210930.xsd#dare_UponCompletionOfFiftyPercentDevelopmentNotLaterThanSixMonthsMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_743873d8-3d84-4684-983a-ae03620c0840" xlink:to="loc_dare_UponCompletionOfFiftyPercentDevelopmentNotLaterThanSixMonthsMember_967e2e03-7f1c-49da-95bd-fcd59838e6a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponDeliveryOfSixMonthBatchDevelopmentNotLaterThanElevenMonthsMember_46ec590d-439f-42cc-9067-6b850ad33cc0" xlink:href="dare-20210930.xsd#dare_UponDeliveryOfSixMonthBatchDevelopmentNotLaterThanElevenMonthsMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_743873d8-3d84-4684-983a-ae03620c0840" xlink:to="loc_dare_UponDeliveryOfSixMonthBatchDevelopmentNotLaterThanElevenMonthsMember_46ec590d-439f-42cc-9067-6b850ad33cc0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_10609438-b5c1-4a7e-92fe-f2e971566c13" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:to="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_10609438-b5c1-4a7e-92fe-f2e971566c13" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyDomain_ef13f684-d270-4651-81dc-06d68fae90f0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RelatedPartyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_10609438-b5c1-4a7e-92fe-f2e971566c13" xlink:to="loc_us-gaap_RelatedPartyDomain_ef13f684-d270-4651-81dc-06d68fae90f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MilanaPharmMember_e97bc685-7e80-40c1-be18-c8938a7ee2c4" xlink:href="dare-20210930.xsd#dare_MilanaPharmMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_ef13f684-d270-4651-81dc-06d68fae90f0" xlink:to="loc_dare_MilanaPharmMember_e97bc685-7e80-40c1-be18-c8938a7ee2c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_HammockPharmaceuticalsInc.Member_b8a81d91-7703-4f53-8415-500d0b28a047" xlink:href="dare-20210930.xsd#dare_HammockPharmaceuticalsInc.Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_ef13f684-d270-4651-81dc-06d68fae90f0" xlink:to="loc_dare_HammockPharmaceuticalsInc.Member_b8a81d91-7703-4f53-8415-500d0b28a047" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_StrategicScienceAndTechnologiesDLimitedLiabilityCompanyAndStrategicScienceTechnologiesLimitedLiabilityCompanyMember_0f561bfa-533d-4ec5-9b67-48f762008b66" xlink:href="dare-20210930.xsd#dare_StrategicScienceAndTechnologiesDLimitedLiabilityCompanyAndStrategicScienceTechnologiesLimitedLiabilityCompanyMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_ef13f684-d270-4651-81dc-06d68fae90f0" xlink:to="loc_dare_StrategicScienceAndTechnologiesDLimitedLiabilityCompanyAndStrategicScienceTechnologiesLimitedLiabilityCompanyMember_0f561bfa-533d-4ec5-9b67-48f762008b66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AdarePharmaceuticalsMember_8d3a7a30-02b0-4d81-89c4-2b081013ad1a" xlink:href="dare-20210930.xsd#dare_AdarePharmaceuticalsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_ef13f684-d270-4651-81dc-06d68fae90f0" xlink:to="loc_dare_AdarePharmaceuticalsMember_8d3a7a30-02b0-4d81-89c4-2b081013ad1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis_e29649b2-fee5-4e5c-b20c-cab06ab1ae9e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis_e29649b2-fee5-4e5c-b20c-cab06ab1ae9e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_9fce232f-712c-41bc-83ae-585d5c4ecaee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis_e29649b2-fee5-4e5c-b20c-cab06ab1ae9e" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_9fce232f-712c-41bc-83ae-585d5c4ecaee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ADVATecAgreementMember_141833a3-da90-482d-98d5-726fb63ebd9f" xlink:href="dare-20210930.xsd#dare_ADVATecAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_9fce232f-712c-41bc-83ae-585d5c4ecaee" xlink:to="loc_dare_ADVATecAgreementMember_141833a3-da90-482d-98d5-726fb63ebd9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ClinicalAndRegulatoryMilestonesMember_5c92a59c-c16e-4d45-a257-ead394a1cb73" xlink:href="dare-20210930.xsd#dare_ClinicalAndRegulatoryMilestonesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_9fce232f-712c-41bc-83ae-585d5c4ecaee" xlink:to="loc_dare_ClinicalAndRegulatoryMilestonesMember_5c92a59c-c16e-4d45-a257-ead394a1cb73" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_SalesMilestonesMember_413560d8-67d5-4df8-945e-80229ca37f30" xlink:href="dare-20210930.xsd#dare_SalesMilestonesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_9fce232f-712c-41bc-83ae-585d5c4ecaee" xlink:to="loc_dare_SalesMilestonesMember_413560d8-67d5-4df8-945e-80229ca37f30" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContingentConsiderationByTypeAxis_907d7ee3-1a11-4324-83dc-e2a87e642481" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ContingentConsiderationByTypeAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:to="loc_us-gaap_ContingentConsiderationByTypeAxis_907d7ee3-1a11-4324-83dc-e2a87e642481" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContingentConsiderationTypeDomain_63bcdc39-7829-4ee3-8658-4dcba4356223" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ContingentConsiderationTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationByTypeAxis_907d7ee3-1a11-4324-83dc-e2a87e642481" xlink:to="loc_us-gaap_ContingentConsiderationTypeDomain_63bcdc39-7829-4ee3-8658-4dcba4356223" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponAchievementOfSpecifiedDevelopmentAndRegulatoryMilestonesMember_47ac1397-2d7b-438e-b68a-8c4451791f60" xlink:href="dare-20210930.xsd#dare_UponAchievementOfSpecifiedDevelopmentAndRegulatoryMilestonesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationTypeDomain_63bcdc39-7829-4ee3-8658-4dcba4356223" xlink:to="loc_dare_UponAchievementOfSpecifiedDevelopmentAndRegulatoryMilestonesMember_47ac1397-2d7b-438e-b68a-8c4451791f60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalizedCostsOfUnprovedPropertiesExcludedFromAmortizationByPropertyOrProjectAxis_83b549f2-3f6b-4c95-9bc0-057feb25f59c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CapitalizedCostsOfUnprovedPropertiesExcludedFromAmortizationByPropertyOrProjectAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:to="loc_us-gaap_CapitalizedCostsOfUnprovedPropertiesExcludedFromAmortizationByPropertyOrProjectAxis_83b549f2-3f6b-4c95-9bc0-057feb25f59c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProjectMember_2cecfd63-9b88-4417-b4ad-f16e2627dce5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProjectMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CapitalizedCostsOfUnprovedPropertiesExcludedFromAmortizationByPropertyOrProjectAxis_83b549f2-3f6b-4c95-9bc0-057feb25f59c" xlink:to="loc_us-gaap_ProjectMember_2cecfd63-9b88-4417-b4ad-f16e2627dce5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponAchievementOfSpecifiedDevelopmentAndRegulatoryMilestonesMember_42bd2564-31ad-4cad-94e5-256fc967d86d" xlink:href="dare-20210930.xsd#dare_UponAchievementOfSpecifiedDevelopmentAndRegulatoryMilestonesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProjectMember_2cecfd63-9b88-4417-b4ad-f16e2627dce5" xlink:to="loc_dare_UponAchievementOfSpecifiedDevelopmentAndRegulatoryMilestonesMember_42bd2564-31ad-4cad-94e5-256fc967d86d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponReachingCertainWorldwideNetSalesMilestonesMember_1234b3b9-fbe6-4e88-8e1e-6e2a751f7649" xlink:href="dare-20210930.xsd#dare_UponReachingCertainWorldwideNetSalesMilestonesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProjectMember_2cecfd63-9b88-4417-b4ad-f16e2627dce5" xlink:to="loc_dare_UponReachingCertainWorldwideNetSalesMilestonesMember_1234b3b9-fbe6-4e88-8e1e-6e2a751f7649" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_fa120691-feec-423d-8ecc-219c6fd3cf4b" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeAxis"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:to="loc_srt_RangeAxis_fa120691-feec-423d-8ecc-219c6fd3cf4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_04256837-45e3-49ef-aa47-5bed6f2a6554" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_fa120691-feec-423d-8ecc-219c6fd3cf4b" xlink:to="loc_srt_RangeMember_04256837-45e3-49ef-aa47-5bed6f2a6554" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_f6b37011-6a4c-4021-b783-9aa9489cb7d9" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MaximumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_04256837-45e3-49ef-aa47-5bed6f2a6554" xlink:to="loc_srt_MaximumMember_f6b37011-6a4c-4021-b783-9aa9489cb7d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_ac00b6cd-4e45-4637-a0bd-522675f0c840" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MinimumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_04256837-45e3-49ef-aa47-5bed6f2a6554" xlink:to="loc_srt_MinimumMember_ac00b6cd-4e45-4637-a0bd-522675f0c840" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_e671a3ab-d823-49d6-8566-cddbf43c11ed" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_e671a3ab-d823-49d6-8566-cddbf43c11ed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_2ae6d9f6-5052-4b63-8227-111bf7031971" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_e671a3ab-d823-49d6-8566-cddbf43c11ed" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_2ae6d9f6-5052-4b63-8227-111bf7031971" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MicrochipsBiotechInc.Member_6073e6e6-e31a-4e97-9396-15e3f1e7dc09" xlink:href="dare-20210930.xsd#dare_MicrochipsBiotechInc.Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_2ae6d9f6-5052-4b63-8227-111bf7031971" xlink:to="loc_dare_MicrochipsBiotechInc.Member_6073e6e6-e31a-4e97-9396-15e3f1e7dc09" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_d45e7f87-84e4-48cd-bb6b-407b26b4abfa" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:to="loc_us-gaap_StatementClassOfStockAxis_d45e7f87-84e4-48cd-bb6b-407b26b4abfa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_828f0e52-7c35-428b-a607-09503510524a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfStockDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_d45e7f87-84e4-48cd-bb6b-407b26b4abfa" xlink:to="loc_us-gaap_ClassOfStockDomain_828f0e52-7c35-428b-a607-09503510524a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_21a38fb5-cfbe-4aab-ac54-0f753d272d7a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_828f0e52-7c35-428b-a607-09503510524a" xlink:to="loc_us-gaap_CommonStockMember_21a38fb5-cfbe-4aab-ac54-0f753d272d7a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_ebfe1922-cd60-4557-8869-ad716aff030f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_ebfe1922-cd60-4557-8869-ad716aff030f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_4c478d19-0f7a-42ee-b20d-46b93d6f319b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_ebfe1922-cd60-4557-8869-ad716aff030f" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_4c478d19-0f7a-42ee-b20d-46b93d6f319b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_a5c64742-9394-4f44-8467-ca44ddd8940f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_4c478d19-0f7a-42ee-b20d-46b93d6f319b" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_a5c64742-9394-4f44-8467-ca44ddd8940f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_fce0a2dd-a713-4e68-b49e-87744ab9b9f2" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:to="loc_srt_CounterpartyNameAxis_fce0a2dd-a713-4e68-b49e-87744ab9b9f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_97b520dc-5909-4654-b358-fdf3eef477a1" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_fce0a2dd-a713-4e68-b49e-87744ab9b9f2" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_97b520dc-5909-4654-b358-fdf3eef477a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MilanaPharmMember_7942d12b-211a-4bc1-83ce-d7e74dcfc130" xlink:href="dare-20210930.xsd#dare_MilanaPharmMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_97b520dc-5909-4654-b358-fdf3eef477a1" xlink:to="loc_dare_MilanaPharmMember_7942d12b-211a-4bc1-83ce-d7e74dcfc130" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_CatalentAndMilanaPharmMember_e7993089-5e04-4190-b8c8-74f479c3a453" xlink:href="dare-20210930.xsd#dare_CatalentAndMilanaPharmMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_97b520dc-5909-4654-b358-fdf3eef477a1" xlink:to="loc_dare_CatalentAndMilanaPharmMember_e7993089-5e04-4190-b8c8-74f479c3a453" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_24c518b0-729a-438f-a7c9-426a2e914ea8" xlink:to="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UpfrontLicenseFeePaid_12907176-3112-459e-8f56-dbeb219f7ff2" xlink:href="dare-20210930.xsd#dare_UpfrontLicenseFeePaid"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_UpfrontLicenseFeePaid_12907176-3112-459e-8f56-dbeb219f7ff2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_18923cea-0b11-4255-9c14-eb0d7f5e29d2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_18923cea-0b11-4255-9c14-eb0d7f5e29d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MilestonePaymentsContingentAmount_5ab0d182-82be-468b-8e9d-8c10e28962f6" xlink:href="dare-20210930.xsd#dare_MilestonePaymentsContingentAmount"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_MilestonePaymentsContingentAmount_5ab0d182-82be-468b-8e9d-8c10e28962f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseAgreementInitialTerm_e63d0017-4b10-4879-bd6d-72b63c8e6154" xlink:href="dare-20210930.xsd#dare_LicenseAgreementInitialTerm"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_LicenseAgreementInitialTerm_e63d0017-4b10-4879-bd6d-72b63c8e6154" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseFee_43d0813a-1eb3-4ad1-9d8a-b6ed800eb2f8" xlink:href="dare-20210930.xsd#dare_LicenseFee"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_LicenseFee_43d0813a-1eb3-4ad1-9d8a-b6ed800eb2f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseFeeToBePaidUponContingency_0021c34a-b210-4477-9250-d15505d969e3" xlink:href="dare-20210930.xsd#dare_LicenseFeeToBePaidUponContingency"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_LicenseFeeToBePaidUponContingency_0021c34a-b210-4477-9250-d15505d969e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseAgreementTerminationPeriodicDiscontinuedSaleOfProduct_33b9381b-f7de-4e6b-8f8e-faf2ed72998b" xlink:href="dare-20210930.xsd#dare_LicenseAgreementTerminationPeriodicDiscontinuedSaleOfProduct"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_LicenseAgreementTerminationPeriodicDiscontinuedSaleOfProduct_33b9381b-f7de-4e6b-8f8e-faf2ed72998b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseAgreementTerminationPeriodDueToPerformanceFailure_ff0604b6-1624-4edb-8628-3ac73f3ded36" xlink:href="dare-20210930.xsd#dare_LicenseAgreementTerminationPeriodDueToPerformanceFailure"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_LicenseAgreementTerminationPeriodDueToPerformanceFailure_ff0604b6-1624-4edb-8628-3ac73f3ded36" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseAgreementNoticePeriodOfTermination_be70f5a5-5dd2-4406-8f8c-a8a2933f4aca" xlink:href="dare-20210930.xsd#dare_LicenseAgreementNoticePeriodOfTermination"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_LicenseAgreementNoticePeriodOfTermination_be70f5a5-5dd2-4406-8f8c-a8a2933f4aca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ResearchAndDevelopmentMilestonePaymentTerm_b200db58-f0cb-423e-9ee7-de5278b5f18e" xlink:href="dare-20210930.xsd#dare_ResearchAndDevelopmentMilestonePaymentTerm"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_ResearchAndDevelopmentMilestonePaymentTerm_b200db58-f0cb-423e-9ee7-de5278b5f18e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ResearchAndDevelopmentMilestonePayment_8e682f9e-77a0-49c0-a429-0df3e761d3fe" xlink:href="dare-20210930.xsd#dare_ResearchAndDevelopmentMilestonePayment"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_ResearchAndDevelopmentMilestonePayment_8e682f9e-77a0-49c0-a429-0df3e761d3fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PercentageOfRoyaltyRate_742a57ed-7d44-4e79-9b53-fe62b3e382de" xlink:href="dare-20210930.xsd#dare_PercentageOfRoyaltyRate"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_PercentageOfRoyaltyRate_742a57ed-7d44-4e79-9b53-fe62b3e382de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PercentageOfRightsToInventionsByEmployeesUnderLicenseAgreement_fa95eae9-151e-4f95-8cb0-5b2027f87e28" xlink:href="dare-20210930.xsd#dare_PercentageOfRightsToInventionsByEmployeesUnderLicenseAgreement"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_PercentageOfRightsToInventionsByEmployeesUnderLicenseAgreement_fa95eae9-151e-4f95-8cb0-5b2027f87e28" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PotentialAnnualLicenseMaintenanceFeePaymentsInYearOne_8e4e0562-0d96-4477-aded-85cfcd7b4588" xlink:href="dare-20210930.xsd#dare_PotentialAnnualLicenseMaintenanceFeePaymentsInYearOne"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_PotentialAnnualLicenseMaintenanceFeePaymentsInYearOne_8e4e0562-0d96-4477-aded-85cfcd7b4588" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PotentialAnnualLicenseMaintenanceFeePaymentsThereafter_1db483d5-10e0-4092-a932-dccf18bcfe68" xlink:href="dare-20210930.xsd#dare_PotentialAnnualLicenseMaintenanceFeePaymentsThereafter"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_PotentialAnnualLicenseMaintenanceFeePaymentsThereafter_1db483d5-10e0-4092-a932-dccf18bcfe68" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MaximumPotentialMilestonePayments_5d20b015-c38c-4c17-a148-73426a0b03a2" xlink:href="dare-20210930.xsd#dare_MaximumPotentialMilestonePayments"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_MaximumPotentialMilestonePayments_5d20b015-c38c-4c17-a148-73426a0b03a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostMaintenance_ce24e4b9-7a0a-4bb3-bef9-689732472f2a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostMaintenance"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_us-gaap_CostMaintenance_ce24e4b9-7a0a-4bb3-bef9-689732472f2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MilestonePaymentsContingentAmountPayableNet_d69bd8e3-e52e-458a-8c9c-c8dcb521140e" xlink:href="dare-20210930.xsd#dare_MilestonePaymentsContingentAmountPayableNet"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_MilestonePaymentsContingentAmountPayableNet_d69bd8e3-e52e-458a-8c9c-c8dcb521140e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_CommencementPeriodForStageTwoUponAchievementOfStageOne_2f35b420-4c31-42d7-96ac-d63590ba02dc" xlink:href="dare-20210930.xsd#dare_CommencementPeriodForStageTwoUponAchievementOfStageOne"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_CommencementPeriodForStageTwoUponAchievementOfStageOne_2f35b420-4c31-42d7-96ac-d63590ba02dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_25b780c5-a6cb-4c8a-8b73-67164d86ddc0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_25b780c5-a6cb-4c8a-8b73-67164d86ddc0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssigned_1e94423b-8911-4aee-9b9d-b9bf169b5f40" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssigned"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_us-gaap_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssigned_1e94423b-8911-4aee-9b9d-b9bf169b5f40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionSharePrice_fbe97497-0e93-4df0-8c85-f7a3d6cceee4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionSharePrice"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_us-gaap_BusinessAcquisitionSharePrice_fbe97497-0e93-4df0-8c85-f7a3d6cceee4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_BusinessCombinationReverseMergerRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_f8a5d508-432d-42bc-b588-ca687d60f646" xlink:href="dare-20210930.xsd#dare_BusinessCombinationReverseMergerRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_BusinessCombinationReverseMergerRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_f8a5d508-432d-42bc-b588-ca687d60f646" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_17b00eda-bfe2-4aea-a083-eb9d95fcb8b7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_17b00eda-bfe2-4aea-a083-eb9d95fcb8b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AssetAcquisitionContingentConsiderationCurrent_88f16058-39d2-4df9-8c0d-4b559ed8fd63" xlink:href="dare-20210930.xsd#dare_AssetAcquisitionContingentConsiderationCurrent"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_AssetAcquisitionContingentConsiderationCurrent_88f16058-39d2-4df9-8c0d-4b559ed8fd63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RegistrationPaymentArrangementMaximumPotentialConsideration_96d15464-8599-443e-9144-358a65589f11" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RegistrationPaymentArrangementMaximumPotentialConsideration"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_us-gaap_RegistrationPaymentArrangementMaximumPotentialConsideration_96d15464-8599-443e-9144-358a65589f11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_db8606e9-944a-4f48-837c-d52533a009c7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_db8606e9-944a-4f48-837c-d52533a009c7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_b344d43c-bd49-433b-a90f-44d006e71a17" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesIssued"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_us-gaap_CommonStockSharesIssued_b344d43c-bd49-433b-a90f-44d006e71a17" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PaymentsToStockholdersRepresentativeInBusinessCombination_34c4a90f-8712-4d2b-83d3-4056270593de" xlink:href="dare-20210930.xsd#dare_PaymentsToStockholdersRepresentativeInBusinessCombination"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_PaymentsToStockholdersRepresentativeInBusinessCombination_34c4a90f-8712-4d2b-83d3-4056270593de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PaymentOfAdditionalConsiderationInBusinessCombination_c70a49be-c04c-453f-8366-afde9df5b7d1" xlink:href="dare-20210930.xsd#dare_PaymentOfAdditionalConsiderationInBusinessCombination"/>
    <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_800711f9-c6ed-4a14-be7f-5937eae8c257" xlink:to="loc_dare_PaymentOfAdditionalConsiderationInBusinessCombination_c70a49be-c04c-453f-8366-afde9df5b7d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockBasedCompensation" xlink:type="simple" xlink:href="dare-20210930.xsd#StockBasedCompensation"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockBasedCompensation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_cd3e7c0f-4027-408a-a64f-8d0ee424df16" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_22ffee18-8d14-45bb-8c91-3026f4972409" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_cd3e7c0f-4027-408a-a64f-8d0ee424df16" xlink:to="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_22ffee18-8d14-45bb-8c91-3026f4972409" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockBasedCompensationTables" xlink:type="simple" xlink:href="dare-20210930.xsd#StockBasedCompensationTables"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockBasedCompensationTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_15a4d0ec-4da8-41bc-ab00-7d87e85dec21" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_921053f9-e469-42d7-8522-e05cb08158a7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_15a4d0ec-4da8-41bc-ab00-7d87e85dec21" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_921053f9-e469-42d7-8522-e05cb08158a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_8622c6f4-7152-4fcd-b4c3-dc4e2060a187" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_15a4d0ec-4da8-41bc-ab00-7d87e85dec21" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_8622c6f4-7152-4fcd-b4c3-dc4e2060a187" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_280afa1e-ce83-4ed8-8e2f-224aa7195c1b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_15a4d0ec-4da8-41bc-ab00-7d87e85dec21" xlink:to="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_280afa1e-ce83-4ed8-8e2f-224aa7195c1b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockBasedCompensationAdditionalInformationDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#StockBasedCompensationAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockBasedCompensationAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_96d20619-09c2-4670-846c-5310f50b1b91" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1cbd1a02-cbe2-4082-bf33-4db645728661" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_96d20619-09c2-4670-846c-5310f50b1b91" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1cbd1a02-cbe2-4082-bf33-4db645728661" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_679a5729-daf3-46e8-85cb-b8b0cb111dc7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PlanNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1cbd1a02-cbe2-4082-bf33-4db645728661" xlink:to="loc_us-gaap_PlanNameAxis_679a5729-daf3-46e8-85cb-b8b0cb111dc7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_53ac6424-0efd-41ed-ae90-46500aca94c3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_679a5729-daf3-46e8-85cb-b8b0cb111dc7" xlink:to="loc_us-gaap_PlanNameDomain_53ac6424-0efd-41ed-ae90-46500aca94c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_TwoThousandAndFourteenEmployeeStockPurchasePlanMember_3d04896e-0b88-42d6-8fc3-000b969fba72" xlink:href="dare-20210930.xsd#dare_TwoThousandAndFourteenEmployeeStockPurchasePlanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_53ac6424-0efd-41ed-ae90-46500aca94c3" xlink:to="loc_dare_TwoThousandAndFourteenEmployeeStockPurchasePlanMember_3d04896e-0b88-42d6-8fc3-000b969fba72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember_14fb2581-9c08-4590-9bc6-502b31d8e131" xlink:href="dare-20210930.xsd#dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_53ac6424-0efd-41ed-ae90-46500aca94c3" xlink:to="loc_dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember_14fb2581-9c08-4590-9bc6-502b31d8e131" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_452e5222-fd0c-4599-93c0-cbafcd638b80" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1cbd1a02-cbe2-4082-bf33-4db645728661" xlink:to="loc_us-gaap_AwardTypeAxis_452e5222-fd0c-4599-93c0-cbafcd638b80" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0f986350-028a-44ad-9b38-39e7ab82e0ac" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_452e5222-fd0c-4599-93c0-cbafcd638b80" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0f986350-028a-44ad-9b38-39e7ab82e0ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_439ac915-644e-4952-be6a-48d8cf4ad241" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0f986350-028a-44ad-9b38-39e7ab82e0ac" xlink:to="loc_us-gaap_EmployeeStockOptionMember_439ac915-644e-4952-be6a-48d8cf4ad241" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_9d1be05d-f839-4f55-bc79-ab7be38d23ab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_1cbd1a02-cbe2-4082-bf33-4db645728661" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_9d1be05d-f839-4f55-bc79-ab7be38d23ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_878a308b-7dc5-4e09-8939-8e0a696b7f96" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_9d1be05d-f839-4f55-bc79-ab7be38d23ab" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_878a308b-7dc5-4e09-8939-8e0a696b7f96" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_78a65cfd-b125-479a-b2bb-213fcf110c03" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_9d1be05d-f839-4f55-bc79-ab7be38d23ab" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_78a65cfd-b125-479a-b2bb-213fcf110c03" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_7e4d7b5e-944b-4188-b696-82eb3a7b8616" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_9d1be05d-f839-4f55-bc79-ab7be38d23ab" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_7e4d7b5e-944b-4188-b696-82eb3a7b8616" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfOutstandingStockMaximum_b4a8bbff-00ad-4fb4-9d61-ec49611e1338" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfOutstandingStockMaximum"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_9d1be05d-f839-4f55-bc79-ab7be38d23ab" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfOutstandingStockMaximum_b4a8bbff-00ad-4fb4-9d61-ec49611e1338" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNumberOfSharesPeriodIncreaseDecrease_175f828f-34d1-486a-833d-77268b7aef20" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNumberOfSharesPeriodIncreaseDecrease"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_9d1be05d-f839-4f55-bc79-ab7be38d23ab" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNumberOfSharesPeriodIncreaseDecrease_175f828f-34d1-486a-833d-77268b7aef20" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_aa2ecc14-2b80-4202-8613-5359ccac17e7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_9d1be05d-f839-4f55-bc79-ab7be38d23ab" xlink:to="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_aa2ecc14-2b80-4202-8613-5359ccac17e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCompensationSharebasedArrangementsLiabilityCurrentAndNoncurrent_7e3351e6-194b-43ab-ad63-a2958c524382" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DeferredCompensationSharebasedArrangementsLiabilityCurrentAndNoncurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_9d1be05d-f839-4f55-bc79-ab7be38d23ab" xlink:to="loc_us-gaap_DeferredCompensationSharebasedArrangementsLiabilityCurrentAndNoncurrent_7e3351e6-194b-43ab-ad63-a2958c524382" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_WeightedAverageAmortizationPeriod_6f861c1e-70fe-4bc2-9a83-e96ff3a48751" xlink:href="dare-20210930.xsd#dare_WeightedAverageAmortizationPeriod"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_9d1be05d-f839-4f55-bc79-ab7be38d23ab" xlink:to="loc_dare_WeightedAverageAmortizationPeriod_6f861c1e-70fe-4bc2-9a83-e96ff3a48751" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockBasedCompensationSummaryofStockOptionActivityforAmended2014PlanandRelatedInformationDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#StockBasedCompensationSummaryofStockOptionActivityforAmended2014PlanandRelatedInformationDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockBasedCompensationSummaryofStockOptionActivityforAmended2014PlanandRelatedInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1338d7f5-0ccb-4e0f-8d0d-f8ec31227e9c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3afee7f4-d8ef-4943-8ef4-b27bbe2fb32b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_1338d7f5-0ccb-4e0f-8d0d-f8ec31227e9c" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3afee7f4-d8ef-4943-8ef4-b27bbe2fb32b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_aa022f99-89be-4108-99bc-79d1b738ecc6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PlanNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3afee7f4-d8ef-4943-8ef4-b27bbe2fb32b" xlink:to="loc_us-gaap_PlanNameAxis_aa022f99-89be-4108-99bc-79d1b738ecc6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_ef8b47be-2f2a-4807-9e11-a4b5df0069bb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_aa022f99-89be-4108-99bc-79d1b738ecc6" xlink:to="loc_us-gaap_PlanNameDomain_ef8b47be-2f2a-4807-9e11-a4b5df0069bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember_93922bfe-cec6-431e-949b-d9e66ba68c84" xlink:href="dare-20210930.xsd#dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_ef8b47be-2f2a-4807-9e11-a4b5df0069bb" xlink:to="loc_dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember_93922bfe-cec6-431e-949b-d9e66ba68c84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_c399a49b-4527-41d7-8dde-91d3b234b80a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3afee7f4-d8ef-4943-8ef4-b27bbe2fb32b" xlink:to="loc_us-gaap_AwardTypeAxis_c399a49b-4527-41d7-8dde-91d3b234b80a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5632f237-b421-4de4-8fbe-579736de336e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_c399a49b-4527-41d7-8dde-91d3b234b80a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5632f237-b421-4de4-8fbe-579736de336e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_5591db6b-f144-4cd4-8f9f-f445fec46bbf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5632f237-b421-4de4-8fbe-579736de336e" xlink:to="loc_us-gaap_EmployeeStockOptionMember_5591db6b-f144-4cd4-8f9f-f445fec46bbf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_787cd1e9-54e3-4128-a591-a7a421eb1696" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3afee7f4-d8ef-4943-8ef4-b27bbe2fb32b" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_787cd1e9-54e3-4128-a591-a7a421eb1696" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_1842fe20-fc4e-487a-9bc7-c0d2182a1642" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_787cd1e9-54e3-4128-a591-a7a421eb1696" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_1842fe20-fc4e-487a-9bc7-c0d2182a1642" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_3be02306-ff18-4c8d-85c6-9fbe211abcb2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_1842fe20-fc4e-487a-9bc7-c0d2182a1642" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_3be02306-ff18-4c8d-85c6-9fbe211abcb2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_bba9b4c2-d620-4df0-8795-ed58cb0aaf42" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_1842fe20-fc4e-487a-9bc7-c0d2182a1642" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_bba9b4c2-d620-4df0-8795-ed58cb0aaf42" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_f75b2e84-cedb-496a-8049-7ff901372773" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_1842fe20-fc4e-487a-9bc7-c0d2182a1642" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_f75b2e84-cedb-496a-8049-7ff901372773" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_1e399e38-f877-4e9e-840f-c2fbd44f386f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_1842fe20-fc4e-487a-9bc7-c0d2182a1642" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_1e399e38-f877-4e9e-840f-c2fbd44f386f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_44803435-a377-44f0-8f56-f0a5d3651c9c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_1842fe20-fc4e-487a-9bc7-c0d2182a1642" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_44803435-a377-44f0-8f56-f0a5d3651c9c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_d5c93f97-43be-441f-91a2-d9908c104587" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_1842fe20-fc4e-487a-9bc7-c0d2182a1642" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_d5c93f97-43be-441f-91a2-d9908c104587" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_dff324e2-08aa-428e-8d27-a1ce545a5e1b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_787cd1e9-54e3-4128-a591-a7a421eb1696" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_dff324e2-08aa-428e-8d27-a1ce545a5e1b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_700d9810-3ebe-403b-b8b1-a18f3db9bd81" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_787cd1e9-54e3-4128-a591-a7a421eb1696" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_700d9810-3ebe-403b-b8b1-a18f3db9bd81" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_65ac78ed-bf5b-4c51-b4cf-f2f079f60d6d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_700d9810-3ebe-403b-b8b1-a18f3db9bd81" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_65ac78ed-bf5b-4c51-b4cf-f2f079f60d6d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_a1396d2e-35fb-4a57-ac71-b281f3b99ba5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_700d9810-3ebe-403b-b8b1-a18f3db9bd81" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_a1396d2e-35fb-4a57-ac71-b281f3b99ba5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_a387a653-192d-47c8-a64c-44249c789eef" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_700d9810-3ebe-403b-b8b1-a18f3db9bd81" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_a387a653-192d-47c8-a64c-44249c789eef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_e8f53d6b-cb01-4c22-8fe7-b302f78eda1d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_700d9810-3ebe-403b-b8b1-a18f3db9bd81" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_e8f53d6b-cb01-4c22-8fe7-b302f78eda1d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice_e4809aab-cb58-4967-bc30-6682e624fe56" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_700d9810-3ebe-403b-b8b1-a18f3db9bd81" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice_e4809aab-cb58-4967-bc30-6682e624fe56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_c8b0dafd-fac8-4c0a-ad92-34ecf3e5f1ad" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_700d9810-3ebe-403b-b8b1-a18f3db9bd81" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_c8b0dafd-fac8-4c0a-ad92-34ecf3e5f1ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_6057d8ca-bc04-470c-937d-2abd45088e1b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_787cd1e9-54e3-4128-a591-a7a421eb1696" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_6057d8ca-bc04-470c-937d-2abd45088e1b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockBasedCompensationSummaryofRecognizedStockBasedCompensationExpenseRelatedtoStockOptionsGrantedtoEmployeesandDirectorsDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#StockBasedCompensationSummaryofRecognizedStockBasedCompensationExpenseRelatedtoStockOptionsGrantedtoEmployeesandDirectorsDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockBasedCompensationSummaryofRecognizedStockBasedCompensationExpenseRelatedtoStockOptionsGrantedtoEmployeesandDirectorsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_79168ae4-6322-47dc-afc3-180d33c60cbf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_9a467540-fdd7-42c6-9300-c2556098e2e7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_79168ae4-6322-47dc-afc3-180d33c60cbf" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_9a467540-fdd7-42c6-9300-c2556098e2e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_0d6e62ad-cf0f-44b2-9655-5de9c00252e7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_9a467540-fdd7-42c6-9300-c2556098e2e7" xlink:to="loc_us-gaap_AwardTypeAxis_0d6e62ad-cf0f-44b2-9655-5de9c00252e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_95696f76-d551-4087-bf5b-d5016e660cdf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_0d6e62ad-cf0f-44b2-9655-5de9c00252e7" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_95696f76-d551-4087-bf5b-d5016e660cdf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_c9097482-95ff-4b5c-ab7d-eeebde3af395" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_95696f76-d551-4087-bf5b-d5016e660cdf" xlink:to="loc_us-gaap_EmployeeStockOptionMember_c9097482-95ff-4b5c-ab7d-eeebde3af395" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_16580812-9711-4398-84ff-f9727b2352d4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_9a467540-fdd7-42c6-9300-c2556098e2e7" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_16580812-9711-4398-84ff-f9727b2352d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_146c1285-1d1d-4ed8-8ec9-a0ead2ae551a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_16580812-9711-4398-84ff-f9727b2352d4" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_146c1285-1d1d-4ed8-8ec9-a0ead2ae551a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_e1646af1-f9f8-40c0-a67f-d03465be9681" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_146c1285-1d1d-4ed8-8ec9-a0ead2ae551a" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_e1646af1-f9f8-40c0-a67f-d03465be9681" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpenseMember_c355fbe3-28bd-42f9-a426-e325536795a4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GeneralAndAdministrativeExpenseMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_146c1285-1d1d-4ed8-8ec9-a0ead2ae551a" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpenseMember_c355fbe3-28bd-42f9-a426-e325536795a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_f30dbbc5-fad5-44cc-b9a9-7011ad9a258c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_9a467540-fdd7-42c6-9300-c2556098e2e7" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_f30dbbc5-fad5-44cc-b9a9-7011ad9a258c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_2a4f677b-e052-4cc3-a116-540de96820c6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_f30dbbc5-fad5-44cc-b9a9-7011ad9a258c" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_2a4f677b-e052-4cc3-a116-540de96820c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockBasedCompensationSummaryofAssumptionsUsedinBlackScholesOptionPricingModelforStockOptionsGrantedtoEmployeesandDirectorsDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#StockBasedCompensationSummaryofAssumptionsUsedinBlackScholesOptionPricingModelforStockOptionsGrantedtoEmployeesandDirectorsDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockBasedCompensationSummaryofAssumptionsUsedinBlackScholesOptionPricingModelforStockOptionsGrantedtoEmployeesandDirectorsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e08dac60-5940-4dcf-a588-14e336b6e748" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_8957b7d6-4642-466d-b470-4ab7b8227702" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e08dac60-5940-4dcf-a588-14e336b6e748" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_8957b7d6-4642-466d-b470-4ab7b8227702" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_486275f6-1239-45bd-aa96-224eda6ab660" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e08dac60-5940-4dcf-a588-14e336b6e748" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_486275f6-1239-45bd-aa96-224eda6ab660" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_ce8aa450-080f-4ec1-be26-603ed6e2a2f8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e08dac60-5940-4dcf-a588-14e336b6e748" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_ce8aa450-080f-4ec1-be26-603ed6e2a2f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsForfeitureRate_9d17c4ea-eca3-4266-8d7f-f5d7095e481a" xlink:href="dare-20210930.xsd#dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsForfeitureRate"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e08dac60-5940-4dcf-a588-14e336b6e748" xlink:to="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsForfeitureRate_9d17c4ea-eca3-4266-8d7f-f5d7095e481a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_edb1d72d-c4a2-45fa-b7ba-38d1885b111d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e08dac60-5940-4dcf-a588-14e336b6e748" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_edb1d72d-c4a2-45fa-b7ba-38d1885b111d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_3598f820-7bd7-4178-9ec8-544dc4e0631f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_e08dac60-5940-4dcf-a588-14e336b6e748" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_3598f820-7bd7-4178-9ec8-544dc4e0631f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockholdersEquity" xlink:type="simple" xlink:href="dare-20210930.xsd#StockholdersEquity"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockholdersEquity" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_3d932d3a-c31a-4647-ad5a-8283a1b5927b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_aef75a89-e2ac-4b42-a609-ef3e0a92563b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_3d932d3a-c31a-4647-ad5a-8283a1b5927b" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_aef75a89-e2ac-4b42-a609-ef3e0a92563b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockholdersEquityTables" xlink:type="simple" xlink:href="dare-20210930.xsd#StockholdersEquityTables"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockholdersEquityTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_8be4684f-6e30-49d6-ab41-2a64b915d762" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock_b0e47bef-3d38-4961-b537-a34a9e95ed22" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_8be4684f-6e30-49d6-ab41-2a64b915d762" xlink:to="loc_us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock_b0e47bef-3d38-4961-b537-a34a9e95ed22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockholdersEquityAdditionalInformationDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#StockholdersEquityAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockholdersEquityAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_4afc88ff-d9da-4346-b2a4-15dbc0987156" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_StockholdersEquityTable_c8a2b0c8-cb2c-4c58-8613-ca747fb916e4" xlink:href="dare-20210930.xsd#dare_StockholdersEquityTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_4afc88ff-d9da-4346-b2a4-15dbc0987156" xlink:to="loc_dare_StockholdersEquityTable_c8a2b0c8-cb2c-4c58-8613-ca747fb916e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_3adab905-d68c-41b7-a30c-a1690d6272cf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityTable_c8a2b0c8-cb2c-4c58-8613-ca747fb916e4" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_3adab905-d68c-41b7-a30c-a1690d6272cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4eb306db-9738-490f-8060-87e9e48f15e0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_3adab905-d68c-41b7-a30c-a1690d6272cf" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4eb306db-9738-490f-8060-87e9e48f15e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AtTheMarketSalesAgreementMember_dbbe48b5-5dfb-454f-a960-c5da3c3583c3" xlink:href="dare-20210930.xsd#dare_AtTheMarketSalesAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4eb306db-9738-490f-8060-87e9e48f15e0" xlink:to="loc_dare_AtTheMarketSalesAgreementMember_dbbe48b5-5dfb-454f-a960-c5da3c3583c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PurchaseAgreementMember_ae0e072e-6a19-4d25-b6d9-81be86920a42" xlink:href="dare-20210930.xsd#dare_PurchaseAgreementMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_4eb306db-9738-490f-8060-87e9e48f15e0" xlink:to="loc_dare_PurchaseAgreementMember_ae0e072e-6a19-4d25-b6d9-81be86920a42" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LegalEntityAxis_c1b36194-2c7a-4e00-8d02-740f6c02d8a9" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_LegalEntityAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityTable_c8a2b0c8-cb2c-4c58-8613-ca747fb916e4" xlink:to="loc_dei_LegalEntityAxis_c1b36194-2c7a-4e00-8d02-740f6c02d8a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityDomain_7bb866bc-e736-489a-b5eb-fa86c85e4fb8" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_LegalEntityAxis_c1b36194-2c7a-4e00-8d02-740f6c02d8a9" xlink:to="loc_dei_EntityDomain_7bb866bc-e736-489a-b5eb-fa86c85e4fb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LincolnParkMember_b7983b9c-a8d0-4ce3-a22e-f944d27761c0" xlink:href="dare-20210930.xsd#dare_LincolnParkMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_7bb866bc-e736-489a-b5eb-fa86c85e4fb8" xlink:to="loc_dare_LincolnParkMember_b7983b9c-a8d0-4ce3-a22e-f944d27761c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_8e80dfa5-a86f-4bc6-a03c-deb0b223c6f1" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityTable_c8a2b0c8-cb2c-4c58-8613-ca747fb916e4" xlink:to="loc_srt_CounterpartyNameAxis_8e80dfa5-a86f-4bc6-a03c-deb0b223c6f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_21214db4-d673-40cd-90bc-68723b17a092" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_8e80dfa5-a86f-4bc6-a03c-deb0b223c6f1" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_21214db4-d673-40cd-90bc-68723b17a092" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LincolnParkMember_1c7a8346-2077-4256-a765-ce371d5cef83" xlink:href="dare-20210930.xsd#dare_LincolnParkMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_21214db4-d673-40cd-90bc-68723b17a092" xlink:to="loc_dare_LincolnParkMember_1c7a8346-2077-4256-a765-ce371d5cef83" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_61628bdf-d3fd-491a-9a9e-0aea8f22fce3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityTable_c8a2b0c8-cb2c-4c58-8613-ca747fb916e4" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_61628bdf-d3fd-491a-9a9e-0aea8f22fce3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfAdoptionMember_0b7bd549-8969-4b5b-9030-361ef05d1f8b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TypeOfAdoptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_61628bdf-d3fd-491a-9a9e-0aea8f22fce3" xlink:to="loc_us-gaap_TypeOfAdoptionMember_0b7bd549-8969-4b5b-9030-361ef05d1f8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingStandardsUpdate201711Member_a749679f-a519-4017-b639-361e1c953c6c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingStandardsUpdate201711Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfAdoptionMember_0b7bd549-8969-4b5b-9030-361ef05d1f8b" xlink:to="loc_us-gaap_AccountingStandardsUpdate201711Member_a749679f-a519-4017-b639-361e1c953c6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:href="dare-20210930.xsd#dare_StockholdersEquityLineItems"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityTable_c8a2b0c8-cb2c-4c58-8613-ca747fb916e4" xlink:to="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_502151d5-67e1-41e0-af30-a740c434af57" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_us-gaap_CommonStockValue_502151d5-67e1-41e0-af30-a740c434af57" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PercentageOfAggregateCommission_960995b3-b54e-4d36-8efe-3febd79d3943" xlink:href="dare-20210930.xsd#dare_PercentageOfAggregateCommission"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_dare_PercentageOfAggregateCommission_960995b3-b54e-4d36-8efe-3febd79d3943" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_2444a854-bfc4-400f-b520-22bdc7c45c60" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_2444a854-bfc4-400f-b520-22bdc7c45c60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_4a4c8649-5a29-4986-b772-aaefa7c2b036" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_4a4c8649-5a29-4986-b772-aaefa7c2b036" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_OfferingExpenses_16464bc3-247e-402d-8b07-62e0d8e697d8" xlink:href="dare-20210930.xsd#dare_OfferingExpenses"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_dare_OfferingExpenses_16464bc3-247e-402d-8b07-62e0d8e697d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligation_76eb5cbb-7aa8-4afa-802a-805d5f400f66" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PurchaseObligation"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_us-gaap_PurchaseObligation_76eb5cbb-7aa8-4afa-802a-805d5f400f66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredOfferingCosts_f62bd58a-19c5-4cda-8b9e-e056b2f6f92d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DeferredOfferingCosts"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_us-gaap_DeferredOfferingCosts_f62bd58a-19c5-4cda-8b9e-e056b2f6f92d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_DeferredOfferingCostsUnamortizedPortion_05b130d9-e399-41b8-ada3-826fb49efc3c" xlink:href="dare-20210930.xsd#dare_DeferredOfferingCostsUnamortizedPortion"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_dare_DeferredOfferingCostsUnamortizedPortion_05b130d9-e399-41b8-ada3-826fb49efc3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_RegularRepurchaseCommonStockIssuable_51d387f2-a46f-4f23-82ad-243a9ec4d593" xlink:href="dare-20210930.xsd#dare_RegularRepurchaseCommonStockIssuable"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_dare_RegularRepurchaseCommonStockIssuable_51d387f2-a46f-4f23-82ad-243a9ec4d593" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfStockIssuanceCosts_e07c1320-653d-4758-917d-abd2a1c92860" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsOfStockIssuanceCosts"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_us-gaap_PaymentsOfStockIssuanceCosts_e07c1320-653d-4758-917d-abd2a1c92860" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_031909b6-d5c3-4128-ba21-761fb594ee9f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_031909b6-d5c3-4128-ba21-761fb594ee9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_EstimatedFairValueOfWarrantsRecordedInEquity_9df53808-69e7-4639-8766-da07707afc79" xlink:href="dare-20210930.xsd#dare_EstimatedFairValueOfWarrantsRecordedInEquity"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_dare_EstimatedFairValueOfWarrantsRecordedInEquity_9df53808-69e7-4639-8766-da07707afc79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantExercisePriceDecrease_5a4f0d2e-0575-4dbd-b141-69a9f58d423a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WarrantExercisePriceDecrease"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_us-gaap_WarrantExercisePriceDecrease_5a4f0d2e-0575-4dbd-b141-69a9f58d423a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_b0a50f48-891d-4b98-b385-cc104c8de689" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_b0a50f48-891d-4b98-b385-cc104c8de689" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_74e83116-871e-4c58-9895-a83812e6bbba" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_74e83116-871e-4c58-9895-a83812e6bbba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_GrossProceedsFromWarrantsExercised_c386c7ec-bbdf-40e9-95cd-3da4ff1aecf6" xlink:href="dare-20210930.xsd#dare_GrossProceedsFromWarrantsExercised"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_StockholdersEquityLineItems_51ffd4dd-9db0-4dc8-91c7-e49f5ce8914b" xlink:to="loc_dare_GrossProceedsFromWarrantsExercised_c386c7ec-bbdf-40e9-95cd-3da4ff1aecf6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockholdersEquityScheduleofCommonStockWarrantsOutstandingDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#StockholdersEquityScheduleofCommonStockWarrantsOutstandingDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockholdersEquityScheduleofCommonStockWarrantsOutstandingDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_4233200b-5656-411f-b5d7-66b99b28df79" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightTable_cc2b600c-481b-4000-a492-b36cd5bdf5f5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_4233200b-5656-411f-b5d7-66b99b28df79" xlink:to="loc_us-gaap_ClassOfWarrantOrRightTable_cc2b600c-481b-4000-a492-b36cd5bdf5f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_103d238e-82b6-4afc-845e-601828bfc9c8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_cc2b600c-481b-4000-a492-b36cd5bdf5f5" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_103d238e-82b6-4afc-845e-601828bfc9c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_46996bd1-9cea-463e-9559-a5566c6eb5de" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_103d238e-82b6-4afc-845e-601828bfc9c8" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_46996bd1-9cea-463e-9559-a5566c6eb5de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_WarrantsExpiringOnDecemberOneTwoThousandTwentyOneMember_89706e5b-d56a-4327-bca8-12f2067c0561" xlink:href="dare-20210930.xsd#dare_WarrantsExpiringOnDecemberOneTwoThousandTwentyOneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_46996bd1-9cea-463e-9559-a5566c6eb5de" xlink:to="loc_dare_WarrantsExpiringOnDecemberOneTwoThousandTwentyOneMember_89706e5b-d56a-4327-bca8-12f2067c0561" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_WarrantsExpiringOnDecemberSixTwoThousandTwentyOneMember_690808d8-aad1-414d-8811-72240a3782ac" xlink:href="dare-20210930.xsd#dare_WarrantsExpiringOnDecemberSixTwoThousandTwentyOneMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_46996bd1-9cea-463e-9559-a5566c6eb5de" xlink:to="loc_dare_WarrantsExpiringOnDecemberSixTwoThousandTwentyOneMember_690808d8-aad1-414d-8811-72240a3782ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_WarrantsExpiringOnAprilFourTwoThousandTwentySixMember_92cad866-9ba8-472e-8ba3-43fbea09b8e7" xlink:href="dare-20210930.xsd#dare_WarrantsExpiringOnAprilFourTwoThousandTwentySixMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_46996bd1-9cea-463e-9559-a5566c6eb5de" xlink:to="loc_dare_WarrantsExpiringOnAprilFourTwoThousandTwentySixMember_92cad866-9ba8-472e-8ba3-43fbea09b8e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_WarrantsExpiringOnFebruaryFifteenTwoThousandTwentyThreeMember_bf4c654c-0a7c-4971-b8af-57e471cd4fe5" xlink:href="dare-20210930.xsd#dare_WarrantsExpiringOnFebruaryFifteenTwoThousandTwentyThreeMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_46996bd1-9cea-463e-9559-a5566c6eb5de" xlink:to="loc_dare_WarrantsExpiringOnFebruaryFifteenTwoThousandTwentyThreeMember_bf4c654c-0a7c-4971-b8af-57e471cd4fe5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightLineItems_3474faf3-5929-40f8-b9dd-9731e85463ab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_cc2b600c-481b-4000-a492-b36cd5bdf5f5" xlink:to="loc_us-gaap_ClassOfWarrantOrRightLineItems_3474faf3-5929-40f8-b9dd-9731e85463ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightOutstanding_df5a18a2-4ca8-4ccc-9fb6-dce1eceb6fab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_3474faf3-5929-40f8-b9dd-9731e85463ab" xlink:to="loc_us-gaap_ClassOfWarrantOrRightOutstanding_df5a18a2-4ca8-4ccc-9fb6-dce1eceb6fab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_1ddbb060-388d-49f9-999b-c690752182a1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_3474faf3-5929-40f8-b9dd-9731e85463ab" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_1ddbb060-388d-49f9-999b-c690752182a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ClassOfWarrantOrRightsWarrantsExpirationDate_23996ae7-8fe4-450d-a8bb-ab5162c3095d" xlink:href="dare-20210930.xsd#dare_ClassOfWarrantOrRightsWarrantsExpirationDate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_3474faf3-5929-40f8-b9dd-9731e85463ab" xlink:to="loc_dare_ClassOfWarrantOrRightsWarrantsExpirationDate_23996ae7-8fe4-450d-a8bb-ab5162c3095d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/LeasedProperties" xlink:type="simple" xlink:href="dare-20210930.xsd#LeasedProperties"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/LeasedProperties" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_f770f209-9f61-487c-b3b9-0e97a8f676d8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeasesTextBlock_73be1577-5105-4fac-acbd-d3f03fae9c9a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeasesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_f770f209-9f61-487c-b3b9-0e97a8f676d8" xlink:to="loc_us-gaap_LesseeOperatingLeasesTextBlock_73be1577-5105-4fac-acbd-d3f03fae9c9a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/LeasedPropertiesTables" xlink:type="simple" xlink:href="dare-20210930.xsd#LeasedPropertiesTables"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/LeasedPropertiesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_ab08abae-cba7-4168-87bb-1576e5250161" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_5d25d23a-6daf-4b65-b6b3-cc892c6c69d6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_ab08abae-cba7-4168-87bb-1576e5250161" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_5d25d23a-6daf-4b65-b6b3-cc892c6c69d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/LeasedPropertiesAdditionalInformationDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#LeasedPropertiesAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/LeasedPropertiesAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_755153da-71fc-4baa-a4db-63130bb862fd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionTable_67a5095d-2b3d-4ae0-923c-5ab0bca238c0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeLeaseDescriptionTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_755153da-71fc-4baa-a4db-63130bb862fd" xlink:to="loc_us-gaap_LesseeLeaseDescriptionTable_67a5095d-2b3d-4ae0-923c-5ab0bca238c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_466e6b6f-df02-462b-a1a5-37def6d73900" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_67a5095d-2b3d-4ae0-923c-5ab0bca238c0" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_466e6b6f-df02-462b-a1a5-37def6d73900" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_58260e58-1f9f-4f75-a333-dfde53ac23c6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BalanceSheetLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_466e6b6f-df02-462b-a1a5-37def6d73900" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_58260e58-1f9f-4f75-a333-dfde53ac23c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncurrentAssetsMember_6b6a56e2-b9d7-48db-a7d8-8ef4e52dcfd1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherNoncurrentAssetsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_58260e58-1f9f-4f75-a333-dfde53ac23c6" xlink:to="loc_us-gaap_OtherNoncurrentAssetsMember_6b6a56e2-b9d7-48db-a7d8-8ef4e52dcfd1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionLineItems_d1b97fa8-a098-4225-a782-26a07398cfd3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_67a5095d-2b3d-4ae0-923c-5ab0bca238c0" xlink:to="loc_us-gaap_LesseeLeaseDescriptionLineItems_d1b97fa8-a098-4225-a782-26a07398cfd3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetRentableArea_2b6cc1b9-8fe3-4e49-b022-5daba7a40e22" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetRentableArea"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_d1b97fa8-a098-4225-a782-26a07398cfd3" xlink:to="loc_us-gaap_NetRentableArea_2b6cc1b9-8fe3-4e49-b022-5daba7a40e22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_61ad2498-44e1-4344-a657-8e33ad35d5a6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseRenewalTerm"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_d1b97fa8-a098-4225-a782-26a07398cfd3" xlink:to="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_61ad2498-44e1-4344-a657-8e33ad35d5a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseDiscountRate_6f6c99b3-ee31-408a-8fec-af12462df383" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseDiscountRate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_d1b97fa8-a098-4225-a782-26a07398cfd3" xlink:to="loc_us-gaap_LesseeOperatingLeaseDiscountRate_6f6c99b3-ee31-408a-8fec-af12462df383" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAssetStatementOfFinancialPositionExtensibleList_1a78dad2-a078-4443-aacc-475f4c292420" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAssetStatementOfFinancialPositionExtensibleList"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_d1b97fa8-a098-4225-a782-26a07398cfd3" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAssetStatementOfFinancialPositionExtensibleList_1a78dad2-a078-4443-aacc-475f4c292420" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_cb5acdaa-b67c-418e-93bb-6ac6f46bef1e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_d1b97fa8-a098-4225-a782-26a07398cfd3" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_cb5acdaa-b67c-418e-93bb-6ac6f46bef1e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_904ca2ae-dde1-4b3c-95f3-98fcb2721df9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_d1b97fa8-a098-4225-a782-26a07398cfd3" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_904ca2ae-dde1-4b3c-95f3-98fcb2721df9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_e7be4dc7-4986-47ec-bad6-fc300ef41985" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_d1b97fa8-a098-4225-a782-26a07398cfd3" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_e7be4dc7-4986-47ec-bad6-fc300ef41985" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseCost_3dee1ec6-00c3-4bc9-838c-d1b83e5ef7e6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseCost"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_d1b97fa8-a098-4225-a782-26a07398cfd3" xlink:to="loc_us-gaap_OperatingLeaseCost_3dee1ec6-00c3-4bc9-838c-d1b83e5ef7e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeasePayments_edbde684-31bb-4d8c-b9ff-65e8e7776a6d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeasePayments"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_d1b97fa8-a098-4225-a782-26a07398cfd3" xlink:to="loc_us-gaap_OperatingLeasePayments_edbde684-31bb-4d8c-b9ff-65e8e7776a6d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_bbda6197-898b-4e40-8c1e-024ed27968b7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_d1b97fa8-a098-4225-a782-26a07398cfd3" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_bbda6197-898b-4e40-8c1e-024ed27968b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/LeasedPropertiesFutureMinimumLeasePaymentsDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#LeasedPropertiesFutureMinimumLeasePaymentsDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/LeasedPropertiesFutureMinimumLeasePaymentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_fa1a6bcb-8cc5-4926-9657-3ddc8d5a9393" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_f127f290-80ca-44a9-ad51-301432383117" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_fa1a6bcb-8cc5-4926-9657-3ddc8d5a9393" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_f127f290-80ca-44a9-ad51-301432383117" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_99c0bb4c-ff43-4dab-8b40-c7cfe3aa4903" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_fa1a6bcb-8cc5-4926-9657-3ddc8d5a9393" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_99c0bb4c-ff43-4dab-8b40-c7cfe3aa4903" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_c84cf870-448b-475d-b5ad-acbb8818ac70" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_fa1a6bcb-8cc5-4926-9657-3ddc8d5a9393" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_c84cf870-448b-475d-b5ad-acbb8818ac70" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_4f3a3cee-c069-4e00-b6ba-857b70a35071" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_fa1a6bcb-8cc5-4926-9657-3ddc8d5a9393" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_4f3a3cee-c069-4e00-b6ba-857b70a35071" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_d5a36bf0-c270-4424-9c43-a7d1744d6f2d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_fa1a6bcb-8cc5-4926-9657-3ddc8d5a9393" xlink:to="loc_us-gaap_OperatingLeaseLiability_d5a36bf0-c270-4424-9c43-a7d1744d6f2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/LeasedPropertiesFutureMinimumLeasePaymentsDetails_1" xlink:type="simple" xlink:href="dare-20210930.xsd#LeasedPropertiesFutureMinimumLeasePaymentsDetails_1"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/LeasedPropertiesFutureMinimumLeasePaymentsDetails_1" xlink:type="extended"/>
  <link:roleRef roleURI="http://darebioscience.com/role/CommitmentsandContingencies" xlink:type="simple" xlink:href="dare-20210930.xsd#CommitmentsandContingencies"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/CommitmentsandContingencies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_964023de-9831-407f-87da-8a3e43125bac" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsDisclosureTextBlock_8c92fa15-b63e-4b1c-9e79-cfe173c5c14a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_964023de-9831-407f-87da-8a3e43125bac" xlink:to="loc_us-gaap_CommitmentsDisclosureTextBlock_8c92fa15-b63e-4b1c-9e79-cfe173c5c14a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/CommitmentsandContingenciesNarrativeDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#CommitmentsandContingenciesNarrativeDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/CommitmentsandContingenciesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_e1657458-6a43-46c2-9d01-3a596b405ac8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_CommitmentsAndContingenciesTable_f4d800fa-18d5-4038-b763-24a0846d71d4" xlink:href="dare-20210930.xsd#dare_CommitmentsAndContingenciesTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_e1657458-6a43-46c2-9d01-3a596b405ac8" xlink:to="loc_dare_CommitmentsAndContingenciesTable_f4d800fa-18d5-4038-b763-24a0846d71d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_3e04d93e-9e8c-4dd8-9944-84056d814d97" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesTable_f4d800fa-18d5-4038-b763-24a0846d71d4" xlink:to="loc_srt_CounterpartyNameAxis_3e04d93e-9e8c-4dd8-9944-84056d814d97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_97373adc-0272-48e1-8960-0c85937eb6c0" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_3e04d93e-9e8c-4dd8-9944-84056d814d97" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_97373adc-0272-48e1-8960-0c85937eb6c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_NICHDMember_dc1e4021-8ecc-4894-8f19-2e2741811094" xlink:href="dare-20210930.xsd#dare_NICHDMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_97373adc-0272-48e1-8960-0c85937eb6c0" xlink:to="loc_dare_NICHDMember_dc1e4021-8ecc-4894-8f19-2e2741811094" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_CRADAMember_ff28e5f5-d407-4822-8284-b1c47b96b0f3" xlink:href="dare-20210930.xsd#dare_CRADAMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_97373adc-0272-48e1-8960-0c85937eb6c0" xlink:to="loc_dare_CRADAMember_ff28e5f5-d407-4822-8284-b1c47b96b0f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_0444edd4-a576-42a0-a770-8e16a5e3733f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesTable_f4d800fa-18d5-4038-b763-24a0846d71d4" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_0444edd4-a576-42a0-a770-8e16a5e3733f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_28d635f0-589c-4d19-ba1d-7431cd12f8c4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_0444edd4-a576-42a0-a770-8e16a5e3733f" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_28d635f0-589c-4d19-ba1d-7431cd12f8c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MicrochipsBiotechInc.Member_e8b5ee97-aa06-4318-90d6-13efec49bc3b" xlink:href="dare-20210930.xsd#dare_MicrochipsBiotechInc.Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_28d635f0-589c-4d19-ba1d-7431cd12f8c4" xlink:to="loc_dare_MicrochipsBiotechInc.Member_e8b5ee97-aa06-4318-90d6-13efec49bc3b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_f99d4d5c-3fe3-4189-b86b-3f0ff45b548d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesTable_f4d800fa-18d5-4038-b763-24a0846d71d4" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_f99d4d5c-3fe3-4189-b86b-3f0ff45b548d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_67df3ec0-aacb-4f99-9613-6fb05fc55a04" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_f99d4d5c-3fe3-4189-b86b-3f0ff45b548d" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_67df3ec0-aacb-4f99-9613-6fb05fc55a04" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_e01e6e25-9383-48ff-9421-6773267f0f28" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_67df3ec0-aacb-4f99-9613-6fb05fc55a04" xlink:to="loc_us-gaap_SubsequentEventMember_e01e6e25-9383-48ff-9421-6773267f0f28" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:href="dare-20210930.xsd#dare_CommitmentsAndContingenciesLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesTable_f4d800fa-18d5-4038-b763-24a0846d71d4" xlink:to="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ResearchAndDevelopmentAgreementCommitmentAmount_19d2813f-8898-4e2b-8312-96bb6238a6c0" xlink:href="dare-20210930.xsd#dare_ResearchAndDevelopmentAgreementCommitmentAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:to="loc_dare_ResearchAndDevelopmentAgreementCommitmentAmount_19d2813f-8898-4e2b-8312-96bb6238a6c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_cc9bfac5-ec7c-4bd3-83cb-33e7c71d59b8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_cc9bfac5-ec7c-4bd3-83cb-33e7c71d59b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueRemainingPerformanceObligation_7002c3fb-5180-4d0e-836d-e57003219631" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueRemainingPerformanceObligation"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:to="loc_us-gaap_RevenueRemainingPerformanceObligation_7002c3fb-5180-4d0e-836d-e57003219631" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PaymentOfAdditionalConsiderationInBusinessCombination_2b448ec5-e064-4247-a727-31de8b93618c" xlink:href="dare-20210930.xsd#dare_PaymentOfAdditionalConsiderationInBusinessCombination"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:to="loc_dare_PaymentOfAdditionalConsiderationInBusinessCombination_2b448ec5-e064-4247-a727-31de8b93618c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RegistrationPaymentArrangementMaximumPotentialConsideration_4b5b866a-f391-4e6c-8b30-448d78441c81" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RegistrationPaymentArrangementMaximumPotentialConsideration"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:to="loc_us-gaap_RegistrationPaymentArrangementMaximumPotentialConsideration_4b5b866a-f391-4e6c-8b30-448d78441c81" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AssetAcquisitionContingentConsiderationCurrent_8191ca98-c4f8-4512-bf1b-49f45691bf01" xlink:href="dare-20210930.xsd#dare_AssetAcquisitionContingentConsiderationCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:to="loc_dare_AssetAcquisitionContingentConsiderationCurrent_8191ca98-c4f8-4512-bf1b-49f45691bf01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_e689dd0b-ea54-42f9-96d4-54f3de79ffa5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_e689dd0b-ea54-42f9-96d4-54f3de79ffa5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_7b7edca5-c9e0-42f7-99ce-46c0755b0d76" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:to="loc_us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_7b7edca5-c9e0-42f7-99ce-46c0755b0d76" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PaymentsToStockholdersRepresentativeInBusinessCombination_67cbe8a2-cf0c-47b2-b17c-5acb861446f7" xlink:href="dare-20210930.xsd#dare_PaymentsToStockholdersRepresentativeInBusinessCombination"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:to="loc_dare_PaymentsToStockholdersRepresentativeInBusinessCombination_67cbe8a2-cf0c-47b2-b17c-5acb861446f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_f5c5ca7c-4e96-4abb-bf22-6737d1f37ff3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_f5c5ca7c-4e96-4abb-bf22-6737d1f37ff3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_CoronavirusAidReliefandEconomicSecurityActLoanProceedsReceived_36e86a61-9734-4c19-b0fa-19ac72b84311" xlink:href="dare-20210930.xsd#dare_CoronavirusAidReliefandEconomicSecurityActLoanProceedsReceived"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:to="loc_dare_CoronavirusAidReliefandEconomicSecurityActLoanProceedsReceived_36e86a61-9734-4c19-b0fa-19ac72b84311" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_NotesPayableCurrentPlusAccruedInterest_4fe6a72a-6c43-4c60-9089-2930bf9f0d3d" xlink:href="dare-20210930.xsd#dare_NotesPayableCurrentPlusAccruedInterest"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_22b5e461-579c-4e54-b67b-1264bb989443" xlink:to="loc_dare_NotesPayableCurrentPlusAccruedInterest_4fe6a72a-6c43-4c60-9089-2930bf9f0d3d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/GrantAwards" xlink:type="simple" xlink:href="dare-20210930.xsd#GrantAwards"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/GrantAwards" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesAbstract_829c990f-cf22-4db6-9923-cd918850c9cf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReceivablesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_GrantAwardTextBlock_f2819e00-6c7e-488f-b9c3-6e311d5f66fe" xlink:href="dare-20210930.xsd#dare_GrantAwardTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_829c990f-cf22-4db6-9923-cd918850c9cf" xlink:to="loc_dare_GrantAwardTextBlock_f2819e00-6c7e-488f-b9c3-6e311d5f66fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/GrantAwardsNarrativeDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#GrantAwardsNarrativeDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/GrantAwardsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesAbstract_0df8ee32-f183-49f1-af13-295c02401ff2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReceivablesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_cb223f22-b2a2-4a15-bbe5-f37007e691cb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_0df8ee32-f183-49f1-af13-295c02401ff2" xlink:to="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_cb223f22-b2a2-4a15-bbe5-f37007e691cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_97200e1a-aac6-40e8-a3ec-03449a44a95a" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_cb223f22-b2a2-4a15-bbe5-f37007e691cb" xlink:to="loc_srt_ProductOrServiceAxis_97200e1a-aac6-40e8-a3ec-03449a44a95a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_53c80f11-9da8-425f-9806-1bf8315675d1" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_97200e1a-aac6-40e8-a3ec-03449a44a95a" xlink:to="loc_srt_ProductsAndServicesDomain_53c80f11-9da8-425f-9806-1bf8315675d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_GrantDAREFRT1Member_0838487a-6b8d-44f0-8775-b3f09184e226" xlink:href="dare-20210930.xsd#dare_GrantDAREFRT1Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_53c80f11-9da8-425f-9806-1bf8315675d1" xlink:to="loc_dare_GrantDAREFRT1Member_0838487a-6b8d-44f0-8775-b3f09184e226" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_DARELARC1Member_fefe5da7-a386-4128-a9bc-d5c5c75c1a77" xlink:href="dare-20210930.xsd#dare_DARELARC1Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_53c80f11-9da8-425f-9806-1bf8315675d1" xlink:to="loc_dare_DARELARC1Member_fefe5da7-a386-4128-a9bc-d5c5c75c1a77" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrantMember_592f908e-6751-4dff-a789-62df4399ca30" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GrantMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_53c80f11-9da8-425f-9806-1bf8315675d1" xlink:to="loc_us-gaap_GrantMember_592f908e-6751-4dff-a789-62df4399ca30" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_HealthCareTrustFundsAxis_e8665074-2b5e-4cb3-91f4-1f07d564f229" xlink:href="dare-20210930.xsd#dare_HealthCareTrustFundsAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_cb223f22-b2a2-4a15-bbe5-f37007e691cb" xlink:to="loc_dare_HealthCareTrustFundsAxis_e8665074-2b5e-4cb3-91f4-1f07d564f229" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_HealthCareTrustFundsDomain_6e711122-f505-4039-9fe7-7748909b32cc" xlink:href="dare-20210930.xsd#dare_HealthCareTrustFundsDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_HealthCareTrustFundsAxis_e8665074-2b5e-4cb3-91f4-1f07d564f229" xlink:to="loc_dare_HealthCareTrustFundsDomain_6e711122-f505-4039-9fe7-7748909b32cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_BillAndMelindaGatesFoundationMember_75f9973a-733a-47f6-ba1c-12c603fccad3" xlink:href="dare-20210930.xsd#dare_BillAndMelindaGatesFoundationMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_HealthCareTrustFundsDomain_6e711122-f505-4039-9fe7-7748909b32cc" xlink:to="loc_dare_BillAndMelindaGatesFoundationMember_75f9973a-733a-47f6-ba1c-12c603fccad3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_1fe6267b-91dd-40b4-a985-6136e46a2877" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsNotesAndLoansReceivableLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_cb223f22-b2a2-4a15-bbe5-f37007e691cb" xlink:to="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_1fe6267b-91dd-40b4-a985-6136e46a2877" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ProceedsFromAwardOfGrant_babf8b47-d052-477c-b78b-ad262ed230fd" xlink:href="dare-20210930.xsd#dare_ProceedsFromAwardOfGrant"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_1fe6267b-91dd-40b4-a985-6136e46a2877" xlink:to="loc_dare_ProceedsFromAwardOfGrant_babf8b47-d052-477c-b78b-ad262ed230fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementWithFederalGovernmentCustomerFundingToOffsetCostsIncurred_d32a038d-0120-4ec3-82bd-c444b976431e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementWithFederalGovernmentCustomerFundingToOffsetCostsIncurred"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_1fe6267b-91dd-40b4-a985-6136e46a2877" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementWithFederalGovernmentCustomerFundingToOffsetCostsIncurred_d32a038d-0120-4ec3-82bd-c444b976431e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AdditionalPotentialFundingRelatedToGrantAward_2feb17dd-969b-4cd1-84ea-52757382db2f" xlink:href="dare-20210930.xsd#dare_AdditionalPotentialFundingRelatedToGrantAward"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_1fe6267b-91dd-40b4-a985-6136e46a2877" xlink:to="loc_dare_AdditionalPotentialFundingRelatedToGrantAward_2feb17dd-969b-4cd1-84ea-52757382db2f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ReceivableForExpensesEligibleForReimbursement_af18c119-43a1-4013-aa44-b49bc809670c" xlink:href="dare-20210930.xsd#dare_ReceivableForExpensesEligibleForReimbursement"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_1fe6267b-91dd-40b4-a985-6136e46a2877" xlink:to="loc_dare_ReceivableForExpensesEligibleForReimbursement_af18c119-43a1-4013-aa44-b49bc809670c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessDevelopment_e7880b64-de17-436a-96d9-e2f44a50537b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BusinessDevelopment"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_1fe6267b-91dd-40b4-a985-6136e46a2877" xlink:to="loc_us-gaap_BusinessDevelopment_e7880b64-de17-436a-96d9-e2f44a50537b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_989e70f5-6679-4cf0-949d-9bcc358d9881" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_1fe6267b-91dd-40b4-a985-6136e46a2877" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_989e70f5-6679-4cf0-949d-9bcc358d9881" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrantsReceivable_d2c07e27-270d-434c-b344-197a3ac0dbda" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GrantsReceivable"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_1fe6267b-91dd-40b4-a985-6136e46a2877" xlink:to="loc_us-gaap_GrantsReceivable_d2c07e27-270d-434c-b344-197a3ac0dbda" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_DeferredGrantFundingCurrent_c9d723d9-9341-4412-b489-55ce9ab58d3d" xlink:href="dare-20210930.xsd#dare_DeferredGrantFundingCurrent"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_1fe6267b-91dd-40b4-a985-6136e46a2877" xlink:to="loc_dare_DeferredGrantFundingCurrent_c9d723d9-9341-4412-b489-55ce9ab58d3d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/NetLossPerShare" xlink:type="simple" xlink:href="dare-20210930.xsd#NetLossPerShare"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/NetLossPerShare" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_461c16e5-bf72-43e2-bddf-754511c56ad5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareTextBlock_35f69cde-3a6d-45b5-be10-0737801ceb63" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_461c16e5-bf72-43e2-bddf-754511c56ad5" xlink:to="loc_us-gaap_EarningsPerShareTextBlock_35f69cde-3a6d-45b5-be10-0737801ceb63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/NetLossPerShareTables" xlink:type="simple" xlink:href="dare-20210930.xsd#NetLossPerShareTables"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/NetLossPerShareTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_282a7219-57c2-4995-9c8c-f35af47a8ea4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_3d0af198-0f9d-4137-bbe1-89801f1204c4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_282a7219-57c2-4995-9c8c-f35af47a8ea4" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_3d0af198-0f9d-4137-bbe1-89801f1204c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/NetLossPerSharePotentialDilutiveOutstandingSecuritiesExcludedFromDilutedNetLossPerCommonShareDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#NetLossPerSharePotentialDilutiveOutstandingSecuritiesExcludedFromDilutedNetLossPerCommonShareDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/NetLossPerSharePotentialDilutiveOutstandingSecuritiesExcludedFromDilutedNetLossPerCommonShareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_c3ceff7a-9672-425e-8e63-e8edbff3692a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_a1065bed-6297-4a90-a91d-cfac694c6c9c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_c3ceff7a-9672-425e-8e63-e8edbff3692a" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_a1065bed-6297-4a90-a91d-cfac694c6c9c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_87750660-a558-4a95-9536-03796bcb4129" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_a1065bed-6297-4a90-a91d-cfac694c6c9c" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_87750660-a558-4a95-9536-03796bcb4129" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_ab91c118-109d-4622-ab07-0ea9d1fb760f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AntidilutiveSecuritiesNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_87750660-a558-4a95-9536-03796bcb4129" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_ab91c118-109d-4622-ab07-0ea9d1fb760f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_7c8cef82-a774-4cb5-b1a5-4116b912f27e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_ab91c118-109d-4622-ab07-0ea9d1fb760f" xlink:to="loc_us-gaap_EmployeeStockOptionMember_7c8cef82-a774-4cb5-b1a5-4116b912f27e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantMember_ebb39028-e035-4ce2-bc8a-e149d02177a2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WarrantMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_ab91c118-109d-4622-ab07-0ea9d1fb760f" xlink:to="loc_us-gaap_WarrantMember_ebb39028-e035-4ce2-bc8a-e149d02177a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_d2ba4b02-393a-4882-ad1f-e6eaac4d9c53" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_a1065bed-6297-4a90-a91d-cfac694c6c9c" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_d2ba4b02-393a-4882-ad1f-e6eaac4d9c53" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_017c14c7-22eb-4d27-88c8-db8e5276a092" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_d2ba4b02-393a-4882-ad1f-e6eaac4d9c53" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_017c14c7-22eb-4d27-88c8-db8e5276a092" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/SubsequentEvents" xlink:type="simple" xlink:href="dare-20210930.xsd#SubsequentEvents"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/SubsequentEvents" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_8136002d-c22b-414d-aa36-1e4e9ee8e308" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsTextBlock_e76947bc-cd92-4ff2-a43b-f7a024528c00" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_8136002d-c22b-414d-aa36-1e4e9ee8e308" xlink:to="loc_us-gaap_SubsequentEventsTextBlock_e76947bc-cd92-4ff2-a43b-f7a024528c00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/SubsequentEventsDetails" xlink:type="simple" xlink:href="dare-20210930.xsd#SubsequentEventsDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/SubsequentEventsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_0daa37ea-2949-4340-ba41-34024d8e22d7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTable_0693657f-5365-4a61-8f1a-87654fde0fdf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_0daa37ea-2949-4340-ba41-34024d8e22d7" xlink:to="loc_us-gaap_SubsequentEventTable_0693657f-5365-4a61-8f1a-87654fde0fdf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_59ca8fc7-1151-492c-8f3d-95b0eee9dd32" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_0693657f-5365-4a61-8f1a-87654fde0fdf" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_59ca8fc7-1151-492c-8f3d-95b0eee9dd32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_46bffa7c-22fc-412d-b231-87cde3e10e1a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_59ca8fc7-1151-492c-8f3d-95b0eee9dd32" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_46bffa7c-22fc-412d-b231-87cde3e10e1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_8ad25b32-9537-4ac3-a3c0-6a769ab65056" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_46bffa7c-22fc-412d-b231-87cde3e10e1a" xlink:to="loc_us-gaap_SubsequentEventMember_8ad25b32-9537-4ac3-a3c0-6a769ab65056" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_82e36e4b-d235-43c9-9d9b-e4dca7573f04" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_0693657f-5365-4a61-8f1a-87654fde0fdf" xlink:to="loc_srt_CounterpartyNameAxis_82e36e4b-d235-43c9-9d9b-e4dca7573f04" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_b1e9030b-2126-4b25-a839-543443f03b78" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_82e36e4b-d235-43c9-9d9b-e4dca7573f04" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_b1e9030b-2126-4b25-a839-543443f03b78" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_NICHDMember_5c17e482-cb0a-46ca-a490-93cb54727885" xlink:href="dare-20210930.xsd#dare_NICHDMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_b1e9030b-2126-4b25-a839-543443f03b78" xlink:to="loc_dare_NICHDMember_5c17e482-cb0a-46ca-a490-93cb54727885" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventLineItems_4680921d-5597-44c9-8b44-e0df99e83e66" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_0693657f-5365-4a61-8f1a-87654fde0fdf" xlink:to="loc_us-gaap_SubsequentEventLineItems_4680921d-5597-44c9-8b44-e0df99e83e66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PercentageOfAggregateCommission_168085cb-f5c1-4311-8f7e-5f2bac4caa24" xlink:href="dare-20210930.xsd#dare_PercentageOfAggregateCommission"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_4680921d-5597-44c9-8b44-e0df99e83e66" xlink:to="loc_dare_PercentageOfAggregateCommission_168085cb-f5c1-4311-8f7e-5f2bac4caa24" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_OfferingProgramGrossAmountAuthorizedUnderSalesAgreement_d6a66c52-9d12-496a-8dc9-4522374b737a" xlink:href="dare-20210930.xsd#dare_OfferingProgramGrossAmountAuthorizedUnderSalesAgreement"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_4680921d-5597-44c9-8b44-e0df99e83e66" xlink:to="loc_dare_OfferingProgramGrossAmountAuthorizedUnderSalesAgreement_d6a66c52-9d12-496a-8dc9-4522374b737a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_4cb79ffd-0a73-430f-82df-3b143daa402f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_4680921d-5597-44c9-8b44-e0df99e83e66" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersCostsIncurredGross_4cb79ffd-0a73-430f-82df-3b143daa402f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
