<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2021 Workiva-->
<!--r:67710cd9-741e-4f56-af84-08464677cdb0,g:f1ade87f-701d-469c-897c-3361ddd63725-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://darebioscience.com/role/CoverPage" xlink:type="simple" xlink:href="dare-20201231.xsd#CoverPage"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/CoverPage" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_42d0d8bf-9b64-41bf-9fd2-f13558cd9014" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_DocumentType_42d0d8bf-9b64-41bf-9fd2-f13558cd9014" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentAnnualReport_851cdbaa-9598-4214-90a0-ab8225fce333" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentAnnualReport"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_DocumentAnnualReport_851cdbaa-9598-4214-90a0-ab8225fce333" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_c14c8558-a37b-41b9-8e1c-1b9c6b5b9576" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_DocumentPeriodEndDate_c14c8558-a37b-41b9-8e1c-1b9c6b5b9576" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate_f60f669e-81bf-4ed6-95a8-e43a3319cbaf" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CurrentFiscalYearEndDate"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_CurrentFiscalYearEndDate_f60f669e-81bf-4ed6-95a8-e43a3319cbaf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentTransitionReport_45b443e6-a688-4c08-8dcc-9b9d96118235" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentTransitionReport"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_DocumentTransitionReport_45b443e6-a688-4c08-8dcc-9b9d96118235" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_a9c06d46-4e38-49df-a9b9-7b592b897601" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityFileNumber_a9c06d46-4e38-49df-a9b9-7b592b897601" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_d8436fd4-ef27-4653-b07f-7c29e5ec1769" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityRegistrantName_d8436fd4-ef27-4653-b07f-7c29e5ec1769" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_336abb5d-03c8-4ae9-acda-7830006b0bd9" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityCentralIndexKey_336abb5d-03c8-4ae9-acda-7830006b0bd9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_b31c796f-b5fb-48d8-a515-10824f1ab6d5" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_AmendmentFlag_b31c796f-b5fb-48d8-a515-10824f1ab6d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalYearFocus_48516e98-5b98-41e1-bdd8-b9bfa2e49862" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentFiscalYearFocus"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_DocumentFiscalYearFocus_48516e98-5b98-41e1-bdd8-b9bfa2e49862" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalPeriodFocus_3b9359cb-4c10-4304-bfbd-e94ff0b54dd3" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_DocumentFiscalPeriodFocus"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_DocumentFiscalPeriodFocus_3b9359cb-4c10-4304-bfbd-e94ff0b54dd3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_a4671f1c-216a-4997-8814-f415db90351e" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityIncorporationStateCountryCode_a4671f1c-216a-4997-8814-f415db90351e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_cb2fa4d8-31ed-4f32-b014-ec860f84459c" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityTaxIdentificationNumber_cb2fa4d8-31ed-4f32-b014-ec860f84459c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_e7c014cd-9eff-4936-9ca7-e26f2281918b" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityAddressAddressLine1_e7c014cd-9eff-4936-9ca7-e26f2281918b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine2_9f7898a4-3781-4810-aad6-c00398081bb4" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressAddressLine2"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityAddressAddressLine2_9f7898a4-3781-4810-aad6-c00398081bb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_f653275c-8ffa-480c-a67d-fa04a25f57f1" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityAddressCityOrTown_f653275c-8ffa-480c-a67d-fa04a25f57f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_6ec6eb93-0966-41f3-b9ae-01619ea74a75" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityAddressStateOrProvince_6ec6eb93-0966-41f3-b9ae-01619ea74a75" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_766781af-ad13-400b-a86d-4e2741c375da" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityAddressPostalZipCode_766781af-ad13-400b-a86d-4e2741c375da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_54304a55-e4df-4135-89f6-1027c80cfe39" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_CityAreaCode_54304a55-e4df-4135-89f6-1027c80cfe39" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_144056fa-3674-4f02-9fc9-48202e60120c" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_LocalPhoneNumber_144056fa-3674-4f02-9fc9-48202e60120c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_72ba1146-5dc7-4f54-a2b5-87651cb9ffa8" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_Security12bTitle_72ba1146-5dc7-4f54-a2b5-87651cb9ffa8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_36094fac-0f8c-465e-a30b-ab7ae98fa754" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_TradingSymbol_36094fac-0f8c-465e-a30b-ab7ae98fa754" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityWellKnownSeasonedIssuer_2e1aa747-3439-4e11-9555-59cf8f8990ca" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityWellKnownSeasonedIssuer"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityWellKnownSeasonedIssuer_2e1aa747-3439-4e11-9555-59cf8f8990ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityVoluntaryFilers_d7df9d43-d7b6-4603-b21a-2ddd64525fae" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityVoluntaryFilers"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityVoluntaryFilers_d7df9d43-d7b6-4603-b21a-2ddd64525fae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus_2edbf573-f2ad-4688-b2c0-45868e373cfd" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityCurrentReportingStatus"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityCurrentReportingStatus_2edbf573-f2ad-4688-b2c0-45868e373cfd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInteractiveDataCurrent_6cd7cd20-77c9-4113-8ee7-d35de49383cf" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityInteractiveDataCurrent"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityInteractiveDataCurrent_6cd7cd20-77c9-4113-8ee7-d35de49383cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory_a4c7dd3c-d1ac-452f-a610-f7fa3129fc1c" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityFilerCategory"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityFilerCategory_a4c7dd3c-d1ac-452f-a610-f7fa3129fc1c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitySmallBusiness_8bc78fe2-a0e5-4cfc-9cba-ecebd5373379" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntitySmallBusiness"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntitySmallBusiness_8bc78fe2-a0e5-4cfc-9cba-ecebd5373379" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_ac7500d5-5e2c-4624-b069-290c6355b6df" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityEmergingGrowthCompany_ac7500d5-5e2c-4624-b069-290c6355b6df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_IcfrAuditorAttestationFlag_25703163-28c8-4305-9e1e-fb7b387df3a8" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_IcfrAuditorAttestationFlag"/>
    <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_IcfrAuditorAttestationFlag_25703163-28c8-4305-9e1e-fb7b387df3a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany_b8b84b9e-8f2b-439f-b85e-3cd82182d7f4" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityShellCompany"/>
    <link:presentationArc order="31" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityShellCompany_b8b84b9e-8f2b-439f-b85e-3cd82182d7f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityPublicFloat_98b93f1e-16b7-4ecf-a4de-3bd6f8cb24fc" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityPublicFloat"/>
    <link:presentationArc order="32" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityPublicFloat_98b93f1e-16b7-4ecf-a4de-3bd6f8cb24fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_8bdb1ce4-590f-43ea-bf54-6b3f5cf8e891" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityCommonStockSharesOutstanding"/>
    <link:presentationArc order="33" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_e74adc9e-50ab-423f-9376-8ad2c74b4d5c" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_8bdb1ce4-590f-43ea-bf54-6b3f5cf8e891" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/ConsolidatedBalanceSheets" xlink:type="simple" xlink:href="dare-20201231.xsd#ConsolidatedBalanceSheets"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/ConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_517db5e9-caa0-4e07-999d-392ab9940786" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsAbstract_52715dce-87cc-406b-a77b-dcf12a682c05" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_517db5e9-caa0-4e07-999d-392ab9940786" xlink:to="loc_us-gaap_AssetsAbstract_52715dce-87cc-406b-a77b-dcf12a682c05" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrentAbstract_e38ab72b-0ac5-4be1-82fe-03172b18836d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_52715dce-87cc-406b-a77b-dcf12a682c05" xlink:to="loc_us-gaap_AssetsCurrentAbstract_e38ab72b-0ac5-4be1-82fe-03172b18836d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_0fab2dd5-fe24-420b-9646-f7dc60a22cb7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_e38ab72b-0ac5-4be1-82fe-03172b18836d" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_0fab2dd5-fe24-420b-9646-f7dc60a22cb7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherReceivablesNetCurrent_b568b6a5-6247-4ec3-a01e-46f26d307ab4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherReceivablesNetCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_e38ab72b-0ac5-4be1-82fe-03172b18836d" xlink:to="loc_us-gaap_OtherReceivablesNetCurrent_b568b6a5-6247-4ec3-a01e-46f26d307ab4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseCurrent_d3a7a559-12f6-45dc-9ed0-f9842ce97532" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PrepaidExpenseCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_e38ab72b-0ac5-4be1-82fe-03172b18836d" xlink:to="loc_us-gaap_PrepaidExpenseCurrent_d3a7a559-12f6-45dc-9ed0-f9842ce97532" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_ddfba0b9-abc7-4bb9-96fb-89ea4d1c81b5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_e38ab72b-0ac5-4be1-82fe-03172b18836d" xlink:to="loc_us-gaap_AssetsCurrent_ddfba0b9-abc7-4bb9-96fb-89ea4d1c81b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_03a69cd2-b4f3-4080-8886-c96bc8384972" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_52715dce-87cc-406b-a77b-dcf12a682c05" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_03a69cd2-b4f3-4080-8886-c96bc8384972" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_8848275d-46ef-489d-9782-42bb8982d71b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_52715dce-87cc-406b-a77b-dcf12a682c05" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_8848275d-46ef-489d-9782-42bb8982d71b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_b905924a-4f9a-4f1a-ba4e-c1660aa7a3b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Assets"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_52715dce-87cc-406b-a77b-dcf12a682c05" xlink:to="loc_us-gaap_Assets_b905924a-4f9a-4f1a-ba4e-c1660aa7a3b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9cf89ed4-00ae-4545-8dd9-31de4791742a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_517db5e9-caa0-4e07-999d-392ab9940786" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9cf89ed4-00ae-4545-8dd9-31de4791742a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_729eb301-78a7-4a19-af23-b0126fa85592" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9cf89ed4-00ae-4545-8dd9-31de4791742a" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_729eb301-78a7-4a19-af23-b0126fa85592" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_d477e7cc-eaaf-46e5-92ae-eb4ddd0fbe3c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_729eb301-78a7-4a19-af23-b0126fa85592" xlink:to="loc_us-gaap_AccountsPayableCurrent_d477e7cc-eaaf-46e5-92ae-eb4ddd0fbe3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_6ce239bf-ae52-4139-b411-8ef72f7135e9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_729eb301-78a7-4a19-af23-b0126fa85592" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_6ce239bf-ae52-4139-b411-8ef72f7135e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_DeferredGrantFundingCurrent_4c6ff99d-b116-4f76-a380-6aec735924f6" xlink:href="dare-20201231.xsd#dare_DeferredGrantFundingCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_729eb301-78a7-4a19-af23-b0126fa85592" xlink:to="loc_dare_DeferredGrantFundingCurrent_4c6ff99d-b116-4f76-a380-6aec735924f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NotesPayableCurrent_a86ad747-f978-4098-9983-9445803484d5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NotesPayableCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_729eb301-78a7-4a19-af23-b0126fa85592" xlink:to="loc_us-gaap_NotesPayableCurrent_a86ad747-f978-4098-9983-9445803484d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent_03238ac7-65e2-412f-9aa9-e6424fcd47c2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_729eb301-78a7-4a19-af23-b0126fa85592" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent_03238ac7-65e2-412f-9aa9-e6424fcd47c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_10fdcfa8-6859-4deb-b52f-f7ec51f977d1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_729eb301-78a7-4a19-af23-b0126fa85592" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_10fdcfa8-6859-4deb-b52f-f7ec51f977d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_a21d2d23-89ce-40ab-a0af-b726af4408e0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_729eb301-78a7-4a19-af23-b0126fa85592" xlink:to="loc_us-gaap_LiabilitiesCurrent_a21d2d23-89ce-40ab-a0af-b726af4408e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_84a59d2b-f86a-4340-8f8e-689da93470dd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractWithCustomerLiabilityNoncurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9cf89ed4-00ae-4545-8dd9-31de4791742a" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_84a59d2b-f86a-4340-8f8e-689da93470dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_4693bcfb-69be-48b3-957d-db59bd462467" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9cf89ed4-00ae-4545-8dd9-31de4791742a" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_4693bcfb-69be-48b3-957d-db59bd462467" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_a505b902-2de7-4044-a398-bd26fcc39b67" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9cf89ed4-00ae-4545-8dd9-31de4791742a" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_a505b902-2de7-4044-a398-bd26fcc39b67" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_52c13ba5-8028-4a58-ba29-1a00957b5782" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Liabilities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9cf89ed4-00ae-4545-8dd9-31de4791742a" xlink:to="loc_us-gaap_Liabilities_52c13ba5-8028-4a58-ba29-1a00957b5782" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_3f078981-1d00-46c2-9f93-84b7130fc563" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9cf89ed4-00ae-4545-8dd9-31de4791742a" xlink:to="loc_us-gaap_CommitmentsAndContingencies_3f078981-1d00-46c2-9f93-84b7130fc563" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityAbstract_b2e49698-b284-45e6-9cb6-a16207bdf568" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityAbstract"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9cf89ed4-00ae-4545-8dd9-31de4791742a" xlink:to="loc_us-gaap_StockholdersEquityAbstract_b2e49698-b284-45e6-9cb6-a16207bdf568" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockValue_334a99a9-7c51-4cba-8e21-22d9c338774c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_b2e49698-b284-45e6-9cb6-a16207bdf568" xlink:to="loc_us-gaap_PreferredStockValue_334a99a9-7c51-4cba-8e21-22d9c338774c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_78335365-239c-43e1-8b7f-d265ef9ec36f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_b2e49698-b284-45e6-9cb6-a16207bdf568" xlink:to="loc_us-gaap_CommonStockValue_78335365-239c-43e1-8b7f-d265ef9ec36f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_e972fadd-85bf-4f7c-9844-a4cedefa777e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_b2e49698-b284-45e6-9cb6-a16207bdf568" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_e972fadd-85bf-4f7c-9844-a4cedefa777e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_0c1de40e-0987-4074-a204-ff197286a878" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdditionalPaidInCapitalCommonStock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_b2e49698-b284-45e6-9cb6-a16207bdf568" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_0c1de40e-0987-4074-a204-ff197286a878" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_d964988d-ef38-4aa5-be48-5dc1b4034ba7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_b2e49698-b284-45e6-9cb6-a16207bdf568" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_d964988d-ef38-4aa5-be48-5dc1b4034ba7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_6c3bc305-246d-47e9-a440-1b0cd0f81c54" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_b2e49698-b284-45e6-9cb6-a16207bdf568" xlink:to="loc_us-gaap_StockholdersEquity_6c3bc305-246d-47e9-a440-1b0cd0f81c54" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_4ee7a7ff-c546-4acd-98aa-b490046f1c85" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_9cf89ed4-00ae-4545-8dd9-31de4791742a" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_4ee7a7ff-c546-4acd-98aa-b490046f1c85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:type="simple" xlink:href="dare-20201231.xsd#ConsolidatedBalanceSheetsParenthetical"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_f5bdbafe-1a3d-4923-9fc8-1759dd4c6665" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_b35e2d3c-4f6a-48ea-a16b-a0b75808d2e0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockParOrStatedValuePerShare"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f5bdbafe-1a3d-4923-9fc8-1759dd4c6665" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_b35e2d3c-4f6a-48ea-a16b-a0b75808d2e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_715ae7df-a68e-4485-b241-0cda8daa914b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockSharesAuthorized"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f5bdbafe-1a3d-4923-9fc8-1759dd4c6665" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_715ae7df-a68e-4485-b241-0cda8daa914b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesIssued_f8f2c1c1-6a2b-4015-9495-c543ecb5138f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockSharesIssued"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f5bdbafe-1a3d-4923-9fc8-1759dd4c6665" xlink:to="loc_us-gaap_PreferredStockSharesIssued_f8f2c1c1-6a2b-4015-9495-c543ecb5138f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_4fbb44d9-49a6-4022-a053-d069f64f6ba8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockSharesOutstanding"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f5bdbafe-1a3d-4923-9fc8-1759dd4c6665" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_4fbb44d9-49a6-4022-a053-d069f64f6ba8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_1ea43efd-c282-4417-b7bc-6065d260e034" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f5bdbafe-1a3d-4923-9fc8-1759dd4c6665" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_1ea43efd-c282-4417-b7bc-6065d260e034" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_c6887daa-9d04-42d3-a755-6550f5c6d087" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f5bdbafe-1a3d-4923-9fc8-1759dd4c6665" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_c6887daa-9d04-42d3-a755-6550f5c6d087" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_a04934e3-6b33-4669-9f31-a921fffea674" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesIssued"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f5bdbafe-1a3d-4923-9fc8-1759dd4c6665" xlink:to="loc_us-gaap_CommonStockSharesIssued_a04934e3-6b33-4669-9f31-a921fffea674" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_67b66e1b-acc0-40c5-af53-a61c6f87b55c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f5bdbafe-1a3d-4923-9fc8-1759dd4c6665" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_67b66e1b-acc0-40c5-af53-a61c6f87b55c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/ConsolidatedStatementsofOperationsandComprehensiveLoss" xlink:type="simple" xlink:href="dare-20201231.xsd#ConsolidatedStatementsofOperationsandComprehensiveLoss"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/ConsolidatedStatementsofOperationsandComprehensiveLoss" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementAbstract_457c2474-7d65-4e55-a3e5-9150d823519e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpensesAbstract_c340b6e4-ce63-4326-86a2-79f1ef659a93" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingExpensesAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_457c2474-7d65-4e55-a3e5-9150d823519e" xlink:to="loc_us-gaap_OperatingExpensesAbstract_c340b6e4-ce63-4326-86a2-79f1ef659a93" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_80097af3-4dba-4639-8861-b50dd12a3a1d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GeneralAndAdministrativeExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_c340b6e4-ce63-4326-86a2-79f1ef659a93" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_80097af3-4dba-4639-8861-b50dd12a3a1d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_af223a17-fabf-40f0-82cc-d203cb10ba56" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_c340b6e4-ce63-4326-86a2-79f1ef659a93" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_af223a17-fabf-40f0-82cc-d203cb10ba56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseFee_f8743164-acf3-4464-84d3-58692f2d2e7f" xlink:href="dare-20201231.xsd#dare_LicenseFee"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_c340b6e4-ce63-4326-86a2-79f1ef659a93" xlink:to="loc_dare_LicenseFee_f8743164-acf3-4464-84d3-58692f2d2e7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_ae22c5ad-330c-486e-aab3-d0c524824ba1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingExpenses"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_c340b6e4-ce63-4326-86a2-79f1ef659a93" xlink:to="loc_us-gaap_OperatingExpenses_ae22c5ad-330c-486e-aab3-d0c524824ba1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_12e5e037-1761-4f53-8d60-3a2aabe888cf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_457c2474-7d65-4e55-a3e5-9150d823519e" xlink:to="loc_us-gaap_OperatingIncomeLoss_12e5e037-1761-4f53-8d60-3a2aabe888cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_e92a400e-183c-4357-babe-d04198987768" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_457c2474-7d65-4e55-a3e5-9150d823519e" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_e92a400e-183c-4357-babe-d04198987768" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_961f4a66-cdad-45d5-8b62-4ea46617c109" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_457c2474-7d65-4e55-a3e5-9150d823519e" xlink:to="loc_us-gaap_NetIncomeLoss_961f4a66-cdad-45d5-8b62-4ea46617c109" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_775ce972-461e-4662-96db-13a4888b5895" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_457c2474-7d65-4e55-a3e5-9150d823519e" xlink:to="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_775ce972-461e-4662-96db-13a4888b5895" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_2b2f2475-c8c1-42c2-a61a-e36e7e19b35e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_457c2474-7d65-4e55-a3e5-9150d823519e" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_2b2f2475-c8c1-42c2-a61a-e36e7e19b35e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_039ea05e-736f-4045-888a-8ac1de4e625e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_457c2474-7d65-4e55-a3e5-9150d823519e" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_039ea05e-736f-4045-888a-8ac1de4e625e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_97f59042-c2f2-4d87-9868-11c9cdebdbd8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_457c2474-7d65-4e55-a3e5-9150d823519e" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_97f59042-c2f2-4d87-9868-11c9cdebdbd8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasicAndDiluted_37631fa6-80c9-45ad-b186-723b03273c32" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerShareBasicAndDiluted"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_457c2474-7d65-4e55-a3e5-9150d823519e" xlink:to="loc_us-gaap_EarningsPerShareBasicAndDiluted_37631fa6-80c9-45ad-b186-723b03273c32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_34e77d61-9355-43e4-8ab5-212446bb69b9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_457c2474-7d65-4e55-a3e5-9150d823519e" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_34e77d61-9355-43e4-8ab5-212446bb69b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_330302ab-885c-4a37-8bb2-d04d869d9413" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_34e77d61-9355-43e4-8ab5-212446bb69b9" xlink:to="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_330302ab-885c-4a37-8bb2-d04d869d9413" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/ConsolidatedStatementofStockholdersEquityDeficit" xlink:type="simple" xlink:href="dare-20201231.xsd#ConsolidatedStatementofStockholdersEquityDeficit"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/ConsolidatedStatementofStockholdersEquityDeficit" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_5b672ad3-7d9b-4d7a-a29d-549b0c290528" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_64a18235-5336-40cc-abd3-c53f7b236657" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_5b672ad3-7d9b-4d7a-a29d-549b0c290528" xlink:to="loc_us-gaap_StatementTable_64a18235-5336-40cc-abd3-c53f7b236657" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_64d05ccf-0977-49e0-8f43-80013b9d57f1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_64a18235-5336-40cc-abd3-c53f7b236657" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_64d05ccf-0977-49e0-8f43-80013b9d57f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_38c679ea-85c9-4673-beaa-61fa187a7363" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_64d05ccf-0977-49e0-8f43-80013b9d57f1" xlink:to="loc_us-gaap_EquityComponentDomain_38c679ea-85c9-4673-beaa-61fa187a7363" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_2d627eba-477b-456c-828f-a0fd54c819b1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_38c679ea-85c9-4673-beaa-61fa187a7363" xlink:to="loc_us-gaap_CommonStockMember_2d627eba-477b-456c-828f-a0fd54c819b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_603d6b8d-85f1-4536-bd91-1d6b33655307" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_38c679ea-85c9-4673-beaa-61fa187a7363" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_603d6b8d-85f1-4536-bd91-1d6b33655307" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_c5c0e1cc-8ed6-4e0d-b372-7b82bd91724a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_38c679ea-85c9-4673-beaa-61fa187a7363" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_c5c0e1cc-8ed6-4e0d-b372-7b82bd91724a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_5faa1fa3-92b0-4031-a01a-178b9e106135" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_38c679ea-85c9-4673-beaa-61fa187a7363" xlink:to="loc_us-gaap_RetainedEarningsMember_5faa1fa3-92b0-4031-a01a-178b9e106135" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_d91cb244-fbff-491c-b48e-c3578b82176f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_64a18235-5336-40cc-abd3-c53f7b236657" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_d91cb244-fbff-491c-b48e-c3578b82176f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_90835b47-a25f-4ca9-8ae9-5e40a36bc36b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_d91cb244-fbff-491c-b48e-c3578b82176f" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_90835b47-a25f-4ca9-8ae9-5e40a36bc36b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PublicStockOfferingMember_bc9daef1-bb4b-4673-9085-fceb4ac0676d" xlink:href="dare-20201231.xsd#dare_PublicStockOfferingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_90835b47-a25f-4ca9-8ae9-5e40a36bc36b" xlink:to="loc_dare_PublicStockOfferingMember_bc9daef1-bb4b-4673-9085-fceb4ac0676d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_a0ca3cf8-f781-46ec-a5b1-2ae95999cff5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_64a18235-5336-40cc-abd3-c53f7b236657" xlink:to="loc_us-gaap_StatementLineItems_a0ca3cf8-f781-46ec-a5b1-2ae95999cff5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_a0ca3cf8-f781-46ec-a5b1-2ae95999cff5" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_ca5c48f7-0930-479e-8e64-17d6afd3b39b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharesOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_SharesOutstanding_ca5c48f7-0930-479e-8e64-17d6afd3b39b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_443433b0-4ef2-449e-ae55-457ffbce4d38" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_StockholdersEquity_443433b0-4ef2-449e-ae55-457ffbce4d38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_45b8d2a9-eedd-4d50-b6e4-f48b4ab125aa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_45b8d2a9-eedd-4d50-b6e4-f48b4ab125aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_cb463bca-fd30-42b3-9f42-8a3631952182" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_cb463bca-fd30-42b3-9f42-8a3631952182" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesAcquisitions_214f3478-5509-477e-85c8-de18550f0666" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesAcquisitions"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesAcquisitions_214f3478-5509-477e-85c8-de18550f0666" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueAcquisitions_f9482b1e-287f-44a5-9610-83902c90ddeb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueAcquisitions"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueAcquisitions_f9482b1e-287f-44a5-9610-83902c90ddeb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_707d7198-04ea-43d8-99fc-f3ff5a810103" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_707d7198-04ea-43d8-99fc-f3ff5a810103" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuable_f714c79e-95e2-4fdb-8256-0cafa10f973e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuable"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferredEquityInterestsIssuedAndIssuable_f714c79e-95e2-4fdb-8256-0cafa10f973e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_ad8c3679-449b-448c-9254-25056516a8f9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_ad8c3679-449b-448c-9254-25056516a8f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_StockIssuedDuringPeriodSharesConsiderationForCommitmentToPurchaseShares_cc5ef876-de04-4138-8f56-38169acaf083" xlink:href="dare-20201231.xsd#dare_StockIssuedDuringPeriodSharesConsiderationForCommitmentToPurchaseShares"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_dare_StockIssuedDuringPeriodSharesConsiderationForCommitmentToPurchaseShares_cc5ef876-de04-4138-8f56-38169acaf083" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_StockIssuedDuringPeriodValueConsiderationForCommitmentToPurchaseShares_b95b1054-a7e6-4a86-92de-258e7397c3c9" xlink:href="dare-20201231.xsd#dare_StockIssuedDuringPeriodValueConsiderationForCommitmentToPurchaseShares"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_dare_StockIssuedDuringPeriodValueConsiderationForCommitmentToPurchaseShares_b95b1054-a7e6-4a86-92de-258e7397c3c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_618a3bd6-64e8-456b-ae42-a3ea58bd47b5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_618a3bd6-64e8-456b-ae42-a3ea58bd47b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_67f026ff-6575-4737-8700-5c253bdc9723" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_67f026ff-6575-4737-8700-5c253bdc9723" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_af6d70c6-314c-4920-a361-df7da3cfe6b7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_af6d70c6-314c-4920-a361-df7da3cfe6b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_dc5888c9-5ed6-456f-927a-f1bc864e0289" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_NetIncomeLoss_dc5888c9-5ed6-456f-927a-f1bc864e0289" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_0b34c1db-9c5d-46d3-b152-f58607147c27" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_0b34c1db-9c5d-46d3-b152-f58607147c27" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_d26d790f-252d-41ab-9476-899d11697ddb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharesOutstanding"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_SharesOutstanding_d26d790f-252d-41ab-9476-899d11697ddb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_d3c21397-9dc6-4266-856f-05aaea66dd08" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_7c7a8d9e-93ce-43a5-b1b3-16994ad2eb48" xlink:to="loc_us-gaap_StockholdersEquity_d3c21397-9dc6-4266-856f-05aaea66dd08" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/ConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="dare-20201231.xsd#ConsolidatedStatementsofCashFlows"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/ConsolidatedStatementsofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_f71b0456-b597-46f1-98fb-e45875e94c42" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_f1f7a9f2-9ee6-4e3c-be5b-a5f0c8c3d973" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f71b0456-b597-46f1-98fb-e45875e94c42" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_f1f7a9f2-9ee6-4e3c-be5b-a5f0c8c3d973" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_e1e3d537-f85c-4f48-a190-2cd67759ee4a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_f1f7a9f2-9ee6-4e3c-be5b-a5f0c8c3d973" xlink:to="loc_us-gaap_NetIncomeLoss_e1e3d537-f85c-4f48-a190-2cd67759ee4a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_5ad37515-ec1c-4c0c-aa8d-221e0eeeb9ce" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_f1f7a9f2-9ee6-4e3c-be5b-a5f0c8c3d973" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_5ad37515-ec1c-4c0c-aa8d-221e0eeeb9ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Depreciation_ce457848-5b66-4521-bcfa-55d12feaca69" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Depreciation"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_5ad37515-ec1c-4c0c-aa8d-221e0eeeb9ce" xlink:to="loc_us-gaap_Depreciation_ce457848-5b66-4521-bcfa-55d12feaca69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_e21c2786-52a3-46a1-84c3-6ffe716c1be3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensation"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_5ad37515-ec1c-4c0c-aa8d-221e0eeeb9ce" xlink:to="loc_us-gaap_ShareBasedCompensation_e21c2786-52a3-46a1-84c3-6ffe716c1be3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_NonCashLeaseExpense_c402d3ca-9bd6-4fdd-b1e4-06d572bfe3db" xlink:href="dare-20201231.xsd#dare_NonCashLeaseExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_5ad37515-ec1c-4c0c-aa8d-221e0eeeb9ce" xlink:to="loc_dare_NonCashLeaseExpense_c402d3ca-9bd6-4fdd-b1e4-06d572bfe3db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentInProcess_8667a650-a2a0-4772-a789-9a6f3b35b117" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResearchAndDevelopmentInProcess"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_5ad37515-ec1c-4c0c-aa8d-221e0eeeb9ce" xlink:to="loc_us-gaap_ResearchAndDevelopmentInProcess_8667a650-a2a0-4772-a789-9a6f3b35b117" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_ebf9fb65-fda2-4d68-bdf7-b730ba00fae1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_5ad37515-ec1c-4c0c-aa8d-221e0eeeb9ce" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_ebf9fb65-fda2-4d68-bdf7-b730ba00fae1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherReceivables_5fbb9b82-aa9c-453d-82dd-ea1dbfe7885f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOtherReceivables"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_ebf9fb65-fda2-4d68-bdf7-b730ba00fae1" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherReceivables_5fbb9b82-aa9c-453d-82dd-ea1dbfe7885f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidExpense_eb7867b6-27eb-4017-ba11-48427b89add6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_ebf9fb65-fda2-4d68-bdf7-b730ba00fae1" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidExpense_eb7867b6-27eb-4017-ba11-48427b89add6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentAssets_c1651b32-248b-4408-a321-a5090a1a793d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOtherNoncurrentAssets"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_ebf9fb65-fda2-4d68-bdf7-b730ba00fae1" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentAssets_c1651b32-248b-4408-a321-a5090a1a793d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_ebd04953-aa04-40de-abdc-e50efeee463a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_ebf9fb65-fda2-4d68-bdf7-b730ba00fae1" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_ebd04953-aa04-40de-abdc-e50efeee463a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_a57881c4-e7db-4355-b9ac-8ae7ab6183ca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_ebf9fb65-fda2-4d68-bdf7-b730ba00fae1" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_a57881c4-e7db-4355-b9ac-8ae7ab6183ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_IncreaseDecreaseInDeferredGrantFunding_d82450f4-136b-4d73-bbf6-78eb600c5773" xlink:href="dare-20201231.xsd#dare_IncreaseDecreaseInDeferredGrantFunding"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_ebf9fb65-fda2-4d68-bdf7-b730ba00fae1" xlink:to="loc_dare_IncreaseDecreaseInDeferredGrantFunding_d82450f4-136b-4d73-bbf6-78eb600c5773" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_7e162407-a984-48b0-b3aa-07e75c040354" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInContractWithCustomerLiability"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_ebf9fb65-fda2-4d68-bdf7-b730ba00fae1" xlink:to="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_7e162407-a984-48b0-b3aa-07e75c040354" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a6746fd7-7aee-4271-b467-2aeb0a950a2b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_f1f7a9f2-9ee6-4e3c-be5b-a5f0c8c3d973" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a6746fd7-7aee-4271-b467-2aeb0a950a2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_f01c6e8d-65a7-45bc-b561-261851c54519" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f71b0456-b597-46f1-98fb-e45875e94c42" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_f01c6e8d-65a7-45bc-b561-261851c54519" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAcquiredFromAcquisition_14e009ba-e352-4532-aeab-91ef9b0a89b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAcquiredFromAcquisition"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_f01c6e8d-65a7-45bc-b561-261851c54519" xlink:to="loc_us-gaap_CashAcquiredFromAcquisition_14e009ba-e352-4532-aeab-91ef9b0a89b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_af79a04d-6749-4e88-9f12-db7ef0e8ecde" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_f01c6e8d-65a7-45bc-b561-261851c54519" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_af79a04d-6749-4e88-9f12-db7ef0e8ecde" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_550e4344-2ccf-4ec5-a383-ce22b9e91e93" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_f01c6e8d-65a7-45bc-b561-261851c54519" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_550e4344-2ccf-4ec5-a383-ce22b9e91e93" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_adef8c5b-be95-4429-80d6-7d29868e8698" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f71b0456-b597-46f1-98fb-e45875e94c42" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_adef8c5b-be95-4429-80d6-7d29868e8698" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_cf9109aa-be66-481f-ae9b-b25d4165cf25" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_adef8c5b-be95-4429-80d6-7d29868e8698" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_cf9109aa-be66-481f-ae9b-b25d4165cf25" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ProceedsFromIssuanceOfCommonStockAndWarrants_ba174302-855f-4de9-a68c-d813443c8176" xlink:href="dare-20201231.xsd#dare_ProceedsFromIssuanceOfCommonStockAndWarrants"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_adef8c5b-be95-4429-80d6-7d29868e8698" xlink:to="loc_dare_ProceedsFromIssuanceOfCommonStockAndWarrants_ba174302-855f-4de9-a68c-d813443c8176" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_faabd36b-25ca-489c-8295-582337e5db4d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_adef8c5b-be95-4429-80d6-7d29868e8698" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_faabd36b-25ca-489c-8295-582337e5db4d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromNotesPayable_a5825816-5286-4139-b82c-2a5eb51f5f59" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromNotesPayable"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_adef8c5b-be95-4429-80d6-7d29868e8698" xlink:to="loc_us-gaap_ProceedsFromNotesPayable_a5825816-5286-4139-b82c-2a5eb51f5f59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_f3d404b4-0d43-4fea-96c2-b70b25089dca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_adef8c5b-be95-4429-80d6-7d29868e8698" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_f3d404b4-0d43-4fea-96c2-b70b25089dca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_eb99ac11-d773-4a98-8c37-f26aec3cc878" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f71b0456-b597-46f1-98fb-e45875e94c42" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_eb99ac11-d773-4a98-8c37-f26aec3cc878" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_fafc3145-c33f-4f7e-813a-8aca3bfb39f7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f71b0456-b597-46f1-98fb-e45875e94c42" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_fafc3145-c33f-4f7e-813a-8aca3bfb39f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_4567f96c-d485-47cc-9874-c84d2814670a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f71b0456-b597-46f1-98fb-e45875e94c42" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_4567f96c-d485-47cc-9874-c84d2814670a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_05505c27-646a-430b-a60c-4a25443c01fc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f71b0456-b597-46f1-98fb-e45875e94c42" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_05505c27-646a-430b-a60c-4a25443c01fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_0bb7e312-2727-46a6-ab66-9c6d97fc6929" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f71b0456-b597-46f1-98fb-e45875e94c42" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_0bb7e312-2727-46a6-ab66-9c6d97fc6929" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_098a53d6-aa90-446f-bb19-40231e8023d4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_0bb7e312-2727-46a6-ab66-9c6d97fc6929" xlink:to="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_098a53d6-aa90-446f-bb19-40231e8023d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_IssuanceCostOnEquityPaidInCommonStock_f2e934af-3565-43b2-a53c-19e101a96d63" xlink:href="dare-20201231.xsd#dare_IssuanceCostOnEquityPaidInCommonStock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_0bb7e312-2727-46a6-ab66-9c6d97fc6929" xlink:to="loc_dare_IssuanceCostOnEquityPaidInCommonStock_f2e934af-3565-43b2-a53c-19e101a96d63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_ed6581d3-a876-4105-a18d-1c914eabbd44" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_0bb7e312-2727-46a6-ab66-9c6d97fc6929" xlink:to="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_ed6581d3-a876-4105-a18d-1c914eabbd44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferred1_0ea66975-9372-4eb1-b69b-12f4f4180d2b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferred1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_0bb7e312-2727-46a6-ab66-9c6d97fc6929" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferred1_0ea66975-9372-4eb1-b69b-12f4f4180d2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/OrganizationandDescriptionofBusiness" xlink:type="simple" xlink:href="dare-20201231.xsd#OrganizationandDescriptionofBusiness"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/OrganizationandDescriptionofBusiness" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_df10fe28-bad1-47f9-8915-9f64dd7afe27" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_4ecaff19-de61-4528-8fe5-034add5efc27" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_df10fe28-bad1-47f9-8915-9f64dd7afe27" xlink:to="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_4ecaff19-de61-4528-8fe5-034add5efc27" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/OrganizationandDescriptionofBusinessDetails" xlink:type="simple" xlink:href="dare-20201231.xsd#OrganizationandDescriptionofBusinessDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/OrganizationandDescriptionofBusinessDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5a4e900b-05d3-4d01-8bb2-43abbd1e3f22" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfOperatingSegments_4a2ca100-edba-4c9f-b497-de2f86b099d4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NumberOfOperatingSegments"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5a4e900b-05d3-4d01-8bb2-43abbd1e3f22" xlink:to="loc_us-gaap_NumberOfOperatingSegments_4a2ca100-edba-4c9f-b497-de2f86b099d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/BasisofPresentationandSummaryofSignificantAccountingPolicies" xlink:type="simple" xlink:href="dare-20201231.xsd#BasisofPresentationandSummaryofSignificantAccountingPolicies"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/BasisofPresentationandSummaryofSignificantAccountingPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_4a3a823e-219f-4772-b1ae-fccd10a2909d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureAndSignificantAccountingPoliciesTextBlock_c03b2a79-2d50-4b2a-a5be-4abf84b81509" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureAndSignificantAccountingPoliciesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_4a3a823e-219f-4772-b1ae-fccd10a2909d" xlink:to="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureAndSignificantAccountingPoliciesTextBlock_c03b2a79-2d50-4b2a-a5be-4abf84b81509" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/BasisofPresentationandSummaryofSignificantAccountingPoliciesPolicies" xlink:type="simple" xlink:href="dare-20201231.xsd#BasisofPresentationandSummaryofSignificantAccountingPoliciesPolicies"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/BasisofPresentationandSummaryofSignificantAccountingPoliciesPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_b57ee9af-eb5b-4103-becc-239b7e0431d4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_b57ee9af-eb5b-4103-becc-239b7e0431d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LiquidityPolicyTextBlock_7c7cb7b4-d5a9-4407-a3f4-c32f1c1f9e60" xlink:href="dare-20201231.xsd#dare_LiquidityPolicyTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_dare_LiquidityPolicyTextBlock_7c7cb7b4-d5a9-4407-a3f4-c32f1c1f9e60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConsolidationPolicyTextBlock_27296f39-ad4f-49a5-b88d-1926ff57fcb2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConsolidationPolicyTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_ConsolidationPolicyTextBlock_27296f39-ad4f-49a5-b88d-1926ff57fcb2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UseOfEstimates_ee896ec3-e6ae-43a7-b8b6-b999134b39a3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UseOfEstimates"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_UseOfEstimates_ee896ec3-e6ae-43a7-b8b6-b999134b39a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_RisksAndUncertaintiesPolicyTextBlock_ab7a3243-bb09-42e0-9fa6-dff4e25b91f3" xlink:href="dare-20201231.xsd#dare_RisksAndUncertaintiesPolicyTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_dare_RisksAndUncertaintiesPolicyTextBlock_ab7a3243-bb09-42e0-9fa6-dff4e25b91f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_319d41b5-774e-4592-b753-2ccf7f49d9d0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_319d41b5-774e-4592-b753-2ccf7f49d9d0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskCreditRisk_d3d9c5ae-e7d8-4c04-b4a7-e29eef711b25" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConcentrationRiskCreditRisk"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_ConcentrationRiskCreditRisk_d3d9c5ae-e7d8-4c04-b4a7-e29eef711b25" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueOfFinancialInstrumentsPolicy_b0b5b631-2594-4f8a-bdef-1e37484d33d7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueOfFinancialInstrumentsPolicy"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_FairValueOfFinancialInstrumentsPolicy_b0b5b631-2594-4f8a-bdef-1e37484d33d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_799d16a4-1443-4b08-8a0b-e3a048a2249f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_799d16a4-1443-4b08-8a0b-e3a048a2249f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeasesPolicyTextBlock_93f6bf07-6ab6-4676-b49a-538bacdf8e41" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeasesPolicyTextBlock"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_LesseeLeasesPolicyTextBlock_93f6bf07-6ab6-4676-b49a-538bacdf8e41" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationsPolicy_52544b85-afd3-4588-9eba-6b4c133660d1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsPolicy"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_BusinessCombinationsPolicy_52544b85-afd3-4588-9eba-6b4c133660d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingPolicyPolicyTextBlock_c91a5380-dfe8-4562-b48c-cdb4be2a8714" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SegmentReportingPolicyPolicyTextBlock"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_SegmentReportingPolicyPolicyTextBlock_c91a5380-dfe8-4562-b48c-cdb4be2a8714" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_ee759de3-5755-4527-a2e0-53a1695accee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResearchAndDevelopmentExpensePolicy"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_ee759de3-5755-4527-a2e0-53a1695accee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerSharePolicyTextBlock_cff146b1-f335-469d-be9a-643ba5e91d54" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EarningsPerSharePolicyTextBlock"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_EarningsPerSharePolicyTextBlock_cff146b1-f335-469d-be9a-643ba5e91d54" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_06092a58-718c-4fcc-aaed-ed6fdb445d10" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_06092a58-718c-4fcc-aaed-ed6fdb445d10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxPolicyTextBlock_9339dd0a-8838-4971-ae00-012ef9f05231" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxPolicyTextBlock"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_IncomeTaxPolicyTextBlock_9339dd0a-8838-4971-ae00-012ef9f05231" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GuaranteesIndemnificationsAndWarrantiesPolicies_647b42d8-c787-4be1-ac5f-fa76ffc37da4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GuaranteesIndemnificationsAndWarrantiesPolicies"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9a453219-31b2-47d7-a0a8-749925ec47ed" xlink:to="loc_us-gaap_GuaranteesIndemnificationsAndWarrantiesPolicies_647b42d8-c787-4be1-ac5f-fa76ffc37da4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/BasisofPresentationandSummaryofSignificantAccountingPoliciesTables" xlink:type="simple" xlink:href="dare-20201231.xsd#BasisofPresentationandSummaryofSignificantAccountingPoliciesTables"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/BasisofPresentationandSummaryofSignificantAccountingPoliciesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_6c9e1b28-962d-4eef-9708-2119ed125d0e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisTextBlock_bd861f56-687a-4428-a237-a95cbbda10d1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnRecurringBasisTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6c9e1b28-962d-4eef-9708-2119ed125d0e" xlink:to="loc_us-gaap_FairValueAssetsMeasuredOnRecurringBasisTextBlock_bd861f56-687a-4428-a237-a95cbbda10d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/BasisofPresentationandSummaryofSignificantAccountingPoliciesAdditionalInformationDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#BasisofPresentationandSummaryofSignificantAccountingPoliciesAdditionalInformationDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/BasisofPresentationandSummaryofSignificantAccountingPoliciesAdditionalInformationDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_aae6e9f4-c8d6-4f24-b201-d3a0c7255c13" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_SignificantAccountingPoliciesTable_58214bfb-1013-4059-a28c-d770f461742c" xlink:href="dare-20201231.xsd#dare_SignificantAccountingPoliciesTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_aae6e9f4-c8d6-4f24-b201-d3a0c7255c13" xlink:to="loc_dare_SignificantAccountingPoliciesTable_58214bfb-1013-4059-a28c-d770f461742c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_ac5e1c64-7b13-4ba4-a499-81655ec6ed74" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesTable_58214bfb-1013-4059-a28c-d770f461742c" xlink:to="loc_us-gaap_PlanNameAxis_ac5e1c64-7b13-4ba4-a499-81655ec6ed74" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_71e5ac87-7fc5-4f67-857d-be1471dbd3be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_ac5e1c64-7b13-4ba4-a499-81655ec6ed74" xlink:to="loc_us-gaap_PlanNameDomain_71e5ac87-7fc5-4f67-857d-be1471dbd3be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember_19878870-c5c8-448d-aada-2df65aa3fe0b" xlink:href="dare-20201231.xsd#dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_71e5ac87-7fc5-4f67-857d-be1471dbd3be" xlink:to="loc_dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember_19878870-c5c8-448d-aada-2df65aa3fe0b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_acbb16c3-068e-490c-b1ba-b3e2b9fa6b35" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesTable_58214bfb-1013-4059-a28c-d770f461742c" xlink:to="loc_us-gaap_AwardTypeAxis_acbb16c3-068e-490c-b1ba-b3e2b9fa6b35" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5f8bb58a-95dc-42b3-9776-fbe8c820fa8a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_acbb16c3-068e-490c-b1ba-b3e2b9fa6b35" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5f8bb58a-95dc-42b3-9776-fbe8c820fa8a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_96c7af6e-6d38-412d-bd2c-b39ddf25ba7b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5f8bb58a-95dc-42b3-9776-fbe8c820fa8a" xlink:to="loc_us-gaap_EmployeeStockOptionMember_96c7af6e-6d38-412d-bd2c-b39ddf25ba7b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ExerciseOfWarrantsOutstandingMember_96891f83-6efc-425e-b64d-e775ea7524c1" xlink:href="dare-20201231.xsd#dare_ExerciseOfWarrantsOutstandingMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5f8bb58a-95dc-42b3-9776-fbe8c820fa8a" xlink:to="loc_dare_ExerciseOfWarrantsOutstandingMember_96891f83-6efc-425e-b64d-e775ea7524c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_f7b54e91-d0ba-4b22-b733-737618afe113" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesTable_58214bfb-1013-4059-a28c-d770f461742c" xlink:to="loc_srt_RangeAxis_f7b54e91-d0ba-4b22-b733-737618afe113" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_4d682c6e-cdff-443b-a800-fe4b5fcc335b" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_f7b54e91-d0ba-4b22-b733-737618afe113" xlink:to="loc_srt_RangeMember_4d682c6e-cdff-443b-a800-fe4b5fcc335b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_0d552bd2-15fd-49a9-b073-72fa0ff6a61c" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_4d682c6e-cdff-443b-a800-fe4b5fcc335b" xlink:to="loc_srt_MinimumMember_0d552bd2-15fd-49a9-b073-72fa0ff6a61c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_8ac7cbe2-fbc5-4d9b-a5f6-44a33eadc8fd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesTable_58214bfb-1013-4059-a28c-d770f461742c" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_8ac7cbe2-fbc5-4d9b-a5f6-44a33eadc8fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_79d6d278-ef05-4a0e-8436-08bbdb569813" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_8ac7cbe2-fbc5-4d9b-a5f6-44a33eadc8fd" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_79d6d278-ef05-4a0e-8436-08bbdb569813" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_56a60605-2c91-4495-b04e-7ae59ddb7f8b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_79d6d278-ef05-4a0e-8436-08bbdb569813" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_56a60605-2c91-4495-b04e-7ae59ddb7f8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_4843fc63-be33-4e90-af02-e291618b0d82" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesTable_58214bfb-1013-4059-a28c-d770f461742c" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_4843fc63-be33-4e90-af02-e291618b0d82" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4380c9d2-5a36-4e61-aaad-35089039d0bb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_4843fc63-be33-4e90-af02-e291618b0d82" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4380c9d2-5a36-4e61-aaad-35089039d0bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_89d4e8b3-55c3-4472-a88f-48e1f9ec129d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4380c9d2-5a36-4e61-aaad-35089039d0bb" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_89d4e8b3-55c3-4472-a88f-48e1f9ec129d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_c958bb74-d148-47c8-8013-22279f37c594" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel3Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4380c9d2-5a36-4e61-aaad-35089039d0bb" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_c958bb74-d148-47c8-8013-22279f37c594" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis_0b354206-6f20-4211-b011-7496cc433170" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TypeOfArrangementAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesTable_58214bfb-1013-4059-a28c-d770f461742c" xlink:to="loc_us-gaap_TypeOfArrangementAxis_0b354206-6f20-4211-b011-7496cc433170" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_698b7f83-c5a3-45d8-8184-a8bdc27950de" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfArrangementAxis_0b354206-6f20-4211-b011-7496cc433170" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_698b7f83-c5a3-45d8-8184-a8bdc27950de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_BayerHealthcareLicenseAgreementMember_21c9f5fd-8d37-4816-a16a-c6f0176dc125" xlink:href="dare-20201231.xsd#dare_BayerHealthcareLicenseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_698b7f83-c5a3-45d8-8184-a8bdc27950de" xlink:to="loc_dare_BayerHealthcareLicenseAgreementMember_21c9f5fd-8d37-4816-a16a-c6f0176dc125" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:href="dare-20201231.xsd#dare_SignificantAccountingPoliciesLineItems"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesTable_58214bfb-1013-4059-a28c-d770f461742c" xlink:to="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_880a4006-1081-45a7-bd6a-60d164dc2b69" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_880a4006-1081-45a7-bd6a-60d164dc2b69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebt_80c5a600-c6a1-4205-a0ff-fcd7e5fbc1a5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConvertibleDebt"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_us-gaap_ConvertibleDebt_80c5a600-c6a1-4205-a0ff-fcd7e5fbc1a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_WorkingCapitalIncreaseDeficit_eb672f22-831b-4206-bc85-c5664c4e26cd" xlink:href="dare-20201231.xsd#dare_WorkingCapitalIncreaseDeficit"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_dare_WorkingCapitalIncreaseDeficit_eb672f22-831b-4206-bc85-c5664c4e26cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_9bf0ac39-4c54-420e-8ed1-223085981c3a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_us-gaap_OperatingIncomeLoss_9bf0ac39-4c54-420e-8ed1-223085981c3a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations_b7e6bfef-d7e3-4594-a1fb-b7f5d698be22" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations_b7e6bfef-d7e3-4594-a1fb-b7f5d698be22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PeriodofInsufficientCashandLiquidityRequirements_761abbcc-d22e-496b-9288-b644ed0008af" xlink:href="dare-20201231.xsd#dare_PeriodofInsufficientCashandLiquidityRequirements"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_dare_PeriodofInsufficientCashandLiquidityRequirements_761abbcc-d22e-496b-9288-b644ed0008af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_GrantFundingRecognizedDuringPeriod_2d755df3-9678-4237-be63-d992045e1de8" xlink:href="dare-20201231.xsd#dare_GrantFundingRecognizedDuringPeriod"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_dare_GrantFundingRecognizedDuringPeriod_2d755df3-9678-4237-be63-d992045e1de8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LettersOfCreditOutstandingAmount_7e1f3e67-4bc7-4e18-81e0-3389e3c7095c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LettersOfCreditOutstandingAmount"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_us-gaap_LettersOfCreditOutstandingAmount_7e1f3e67-4bc7-4e18-81e0-3389e3c7095c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFDICInsuredAmount_476f8d35-4b0e-4988-902a-4a890c4d8da6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashFDICInsuredAmount"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_us-gaap_CashFDICInsuredAmount_476f8d35-4b0e-4988-902a-4a890c4d8da6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UpfrontLicenseFeePaid_2d981812-66ee-4f51-8df6-b323052b8533" xlink:href="dare-20201231.xsd#dare_UpfrontLicenseFeePaid"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_dare_UpfrontLicenseFeePaid_2d981812-66ee-4f51-8df6-b323052b8533" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_266910ba-84e3-4e90-98dd-a0ef1bead872" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_266910ba-84e3-4e90-98dd-a0ef1bead872" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MilestonePaymentsContingentAmount_075a469b-e289-4ae5-86a2-31a54d3c20db" xlink:href="dare-20201231.xsd#dare_MilestonePaymentsContingentAmount"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_dare_MilestonePaymentsContingentAmount_075a469b-e289-4ae5-86a2-31a54d3c20db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_4acf19db-7586-4229-8f01-6884ead4d16b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_4acf19db-7586-4229-8f01-6884ead4d16b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_e30c3edc-583b-4fa2-be05-b50dfd8a78a1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_e30c3edc-583b-4fa2-be05-b50dfd8a78a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_96927036-a24c-4a21-aa30-26cf12f18be1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_96927036-a24c-4a21-aa30-26cf12f18be1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefits_17bb10fb-3bed-4678-9f00-643ee4d9b6a1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefits"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_us-gaap_UnrecognizedTaxBenefits_17bb10fb-3bed-4678-9f00-643ee4d9b6a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AccruedIndemnificationProvisions_c1dde6a8-3121-40b0-b5f6-806d9ed5ef72" xlink:href="dare-20201231.xsd#dare_AccruedIndemnificationProvisions"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_SignificantAccountingPoliciesLineItems_17068121-bc66-4526-a61d-9c9c656255b7" xlink:to="loc_dare_AccruedIndemnificationProvisions_c1dde6a8-3121-40b0-b5f6-806d9ed5ef72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/BasisofPresentationandSummaryofSignificantAccountingPoliciesFinancialAssetsandLiabilitiesRemeasuredonaRecurringBasisDetails" xlink:type="simple" xlink:href="dare-20201231.xsd#BasisofPresentationandSummaryofSignificantAccountingPoliciesFinancialAssetsandLiabilitiesRemeasuredonaRecurringBasisDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/BasisofPresentationandSummaryofSignificantAccountingPoliciesFinancialAssetsandLiabilitiesRemeasuredonaRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_1bbf6278-7665-43e3-bfa7-6f017b8a2edc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_c4dd8133-00d6-4ea1-b6db-1160454c2b18" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_1bbf6278-7665-43e3-bfa7-6f017b8a2edc" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_c4dd8133-00d6-4ea1-b6db-1160454c2b18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_7b483be5-f39d-40d1-ba70-9e9d5b7efb26" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_c4dd8133-00d6-4ea1-b6db-1160454c2b18" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_7b483be5-f39d-40d1-ba70-9e9d5b7efb26" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_c6d8f9ed-b301-44a7-8a36-35c942607b9f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_7b483be5-f39d-40d1-ba70-9e9d5b7efb26" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_c6d8f9ed-b301-44a7-8a36-35c942607b9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_5b77a274-3050-4d92-bccf-1936c42c8dd9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_c6d8f9ed-b301-44a7-8a36-35c942607b9f" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_5b77a274-3050-4d92-bccf-1936c42c8dd9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_915e91d9-b58e-45fc-95d5-997d2adb0019" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_c4dd8133-00d6-4ea1-b6db-1160454c2b18" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_915e91d9-b58e-45fc-95d5-997d2adb0019" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_d8bee7ff-216d-484d-9054-f271e4a2d720" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_915e91d9-b58e-45fc-95d5-997d2adb0019" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_d8bee7ff-216d-484d-9054-f271e4a2d720" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_359e3fcf-0bc2-4d6f-a7af-b1e657901ca2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_d8bee7ff-216d-484d-9054-f271e4a2d720" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_359e3fcf-0bc2-4d6f-a7af-b1e657901ca2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_14db0911-30cb-4175-9b48-0f95dce8b397" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel2Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_d8bee7ff-216d-484d-9054-f271e4a2d720" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_14db0911-30cb-4175-9b48-0f95dce8b397" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_dc4164f5-f539-48c3-a73b-71d397b70316" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueInputsLevel3Member"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_d8bee7ff-216d-484d-9054-f271e4a2d720" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_dc4164f5-f539-48c3-a73b-71d397b70316" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_1513bb34-6bd1-477b-a7c5-aff1f6ccafa8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_c4dd8133-00d6-4ea1-b6db-1160454c2b18" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_1513bb34-6bd1-477b-a7c5-aff1f6ccafa8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_b82bd8fa-1c7b-4fdc-a08b-29e073ac8ccb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_1513bb34-6bd1-477b-a7c5-aff1f6ccafa8" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_b82bd8fa-1c7b-4fdc-a08b-29e073ac8ccb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AssetAcquisitionContingentConsiderationCurrent_0338ec64-2ab6-41e5-83b4-5351694349e4" xlink:href="dare-20201231.xsd#dare_AssetAcquisitionContingentConsiderationCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_1513bb34-6bd1-477b-a7c5-aff1f6ccafa8" xlink:to="loc_dare_AssetAcquisitionContingentConsiderationCurrent_0338ec64-2ab6-41e5-83b4-5351694349e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AssetAcquisitionContingentConsiderationNoncurrent_b613b801-058e-464f-a905-351041fab82a" xlink:href="dare-20201231.xsd#dare_AssetAcquisitionContingentConsiderationNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_1513bb34-6bd1-477b-a7c5-aff1f6ccafa8" xlink:to="loc_dare_AssetAcquisitionContingentConsiderationNoncurrent_b613b801-058e-464f-a905-351041fab82a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/LicenseandCollaborationAgreements" xlink:type="simple" xlink:href="dare-20201231.xsd#LicenseandCollaborationAgreements"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/LicenseandCollaborationAgreements" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3d96a95a-1391-48a5-b3d2-d255b0cbfb74" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_90582dd5-5ac2-4127-a987-67cfb2518c69" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CollaborativeArrangementDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_3d96a95a-1391-48a5-b3d2-d255b0cbfb74" xlink:to="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_90582dd5-5ac2-4127-a987-67cfb2518c69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/LicenseandCollaborationAgreementsAdditionalInformationDetails" xlink:type="simple" xlink:href="dare-20201231.xsd#LicenseandCollaborationAgreementsAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/LicenseandCollaborationAgreementsAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_bb60841b-75fd-4a00-ac19-94d0710746d9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_171a2c06-b018-4f43-bcdd-dd6b44da1c5f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_bb60841b-75fd-4a00-ac19-94d0710746d9" xlink:to="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_171a2c06-b018-4f43-bcdd-dd6b44da1c5f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfArrangementAxis_fa51c69d-fac8-48ac-8d37-180314134e63" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TypeOfArrangementAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_171a2c06-b018-4f43-bcdd-dd6b44da1c5f" xlink:to="loc_us-gaap_TypeOfArrangementAxis_fa51c69d-fac8-48ac-8d37-180314134e63" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_048bdfcc-7ba8-4053-9778-505d3e917cca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ArrangementsAndNonarrangementTransactionsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfArrangementAxis_fa51c69d-fac8-48ac-8d37-180314134e63" xlink:to="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_048bdfcc-7ba8-4053-9778-505d3e917cca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_BayerHealthcareLicenseAgreementMember_5bd4113e-3e65-4ffd-9eb5-9895e964aba3" xlink:href="dare-20201231.xsd#dare_BayerHealthcareLicenseAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_048bdfcc-7ba8-4053-9778-505d3e917cca" xlink:to="loc_dare_BayerHealthcareLicenseAgreementMember_5bd4113e-3e65-4ffd-9eb5-9895e964aba3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LicensingAgreementsMember_b5357855-a2ad-4b7d-af35-589088606718" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LicensingAgreementsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_048bdfcc-7ba8-4053-9778-505d3e917cca" xlink:to="loc_us-gaap_LicensingAgreementsMember_b5357855-a2ad-4b7d-af35-589088606718" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AssignmentAgreementMember_0473c341-d896-476e-bc70-eb4b51fd32a3" xlink:href="dare-20201231.xsd#dare_AssignmentAgreementMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_048bdfcc-7ba8-4053-9778-505d3e917cca" xlink:to="loc_dare_AssignmentAgreementMember_0473c341-d896-476e-bc70-eb4b51fd32a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseAndCollaborationAgreementMember_ac8910c3-10f4-4ae6-b6d7-4b24b33b0752" xlink:href="dare-20201231.xsd#dare_LicenseAndCollaborationAgreementMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_048bdfcc-7ba8-4053-9778-505d3e917cca" xlink:to="loc_dare_LicenseAndCollaborationAgreementMember_ac8910c3-10f4-4ae6-b6d7-4b24b33b0752" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_JuniperPharmaceuticalsInc.Member_0a28ea83-66de-411c-a4ef-ada5bbc097c5" xlink:href="dare-20201231.xsd#dare_JuniperPharmaceuticalsInc.Member"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_048bdfcc-7ba8-4053-9778-505d3e917cca" xlink:to="loc_dare_JuniperPharmaceuticalsInc.Member_0a28ea83-66de-411c-a4ef-ada5bbc097c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_DevelopmentAndOptionAgreementMember_129cea7a-2fe8-4288-8015-71acc9e47fb0" xlink:href="dare-20201231.xsd#dare_DevelopmentAndOptionAgreementMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ArrangementsAndNonarrangementTransactionsMember_048bdfcc-7ba8-4053-9778-505d3e917cca" xlink:to="loc_dare_DevelopmentAndOptionAgreementMember_129cea7a-2fe8-4288-8015-71acc9e47fb0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionAxis_aa98b434-c5b4-4825-a5fb-5397a9ea4160" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_171a2c06-b018-4f43-bcdd-dd6b44da1c5f" xlink:to="loc_us-gaap_RelatedPartyTransactionAxis_aa98b434-c5b4-4825-a5fb-5397a9ea4160" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionDomain_643beed8-a074-4dda-8bdf-230456b0ba9b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionAxis_aa98b434-c5b4-4825-a5fb-5397a9ea4160" xlink:to="loc_us-gaap_RelatedPartyTransactionDomain_643beed8-a074-4dda-8bdf-230456b0ba9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponAchievingCertainDevelopmentMilestonesMember_c25f2412-960e-47b7-9d8f-d415d86a3d45" xlink:href="dare-20201231.xsd#dare_UponAchievingCertainDevelopmentMilestonesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_643beed8-a074-4dda-8bdf-230456b0ba9b" xlink:to="loc_dare_UponAchievingCertainDevelopmentMilestonesMember_c25f2412-960e-47b7-9d8f-d415d86a3d45" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponAchievingCertainCommercialMilestonesMember_4732141f-7afb-4a60-82f8-f45dfe627761" xlink:href="dare-20201231.xsd#dare_UponAchievingCertainCommercialMilestonesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_643beed8-a074-4dda-8bdf-230456b0ba9b" xlink:to="loc_dare_UponAchievingCertainCommercialMilestonesMember_4732141f-7afb-4a60-82f8-f45dfe627761" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponAchievingCertainClinicalAndRegulatoryDevelopmentMilestonesMember_9e088652-f610-4a28-bd55-e7335381286f" xlink:href="dare-20201231.xsd#dare_UponAchievingCertainClinicalAndRegulatoryDevelopmentMilestonesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_643beed8-a074-4dda-8bdf-230456b0ba9b" xlink:to="loc_dare_UponAchievingCertainClinicalAndRegulatoryDevelopmentMilestonesMember_9e088652-f610-4a28-bd55-e7335381286f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponSigningOfDevelopmentAndOptionAgreementMember_6c7297c1-5b50-43f7-9aa5-592540f6068c" xlink:href="dare-20201231.xsd#dare_UponSigningOfDevelopmentAndOptionAgreementMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_643beed8-a074-4dda-8bdf-230456b0ba9b" xlink:to="loc_dare_UponSigningOfDevelopmentAndOptionAgreementMember_6c7297c1-5b50-43f7-9aa5-592540f6068c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponCompletionOfFiftyPercentDevelopmentNotLaterThanSixMonthsMember_0cffc1e9-e1c7-4b0f-b73f-31c915ecc993" xlink:href="dare-20201231.xsd#dare_UponCompletionOfFiftyPercentDevelopmentNotLaterThanSixMonthsMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_643beed8-a074-4dda-8bdf-230456b0ba9b" xlink:to="loc_dare_UponCompletionOfFiftyPercentDevelopmentNotLaterThanSixMonthsMember_0cffc1e9-e1c7-4b0f-b73f-31c915ecc993" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponDeliveryOfSixMonthBatchDevelopmentNotLaterThanElevenMonthsMember_f0c771f7-1939-47d0-8e6c-b33a5e68e9bd" xlink:href="dare-20201231.xsd#dare_UponDeliveryOfSixMonthBatchDevelopmentNotLaterThanElevenMonthsMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_643beed8-a074-4dda-8bdf-230456b0ba9b" xlink:to="loc_dare_UponDeliveryOfSixMonthBatchDevelopmentNotLaterThanElevenMonthsMember_f0c771f7-1939-47d0-8e6c-b33a5e68e9bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_db60ad54-6b9c-4435-a225-f59566f7893d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_171a2c06-b018-4f43-bcdd-dd6b44da1c5f" xlink:to="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_db60ad54-6b9c-4435-a225-f59566f7893d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyDomain_bf5f4056-bbf5-434f-91e6-cf3b82525db5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RelatedPartyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_db60ad54-6b9c-4435-a225-f59566f7893d" xlink:to="loc_us-gaap_RelatedPartyDomain_bf5f4056-bbf5-434f-91e6-cf3b82525db5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MilanaPharmMember_307a613b-afb1-4710-a97f-5e809349d830" xlink:href="dare-20201231.xsd#dare_MilanaPharmMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_bf5f4056-bbf5-434f-91e6-cf3b82525db5" xlink:to="loc_dare_MilanaPharmMember_307a613b-afb1-4710-a97f-5e809349d830" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_HammockPharmaceuticalsInc.Member_f78cc315-0f29-4098-ba7a-6a418ebf5a8a" xlink:href="dare-20201231.xsd#dare_HammockPharmaceuticalsInc.Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_bf5f4056-bbf5-434f-91e6-cf3b82525db5" xlink:to="loc_dare_HammockPharmaceuticalsInc.Member_f78cc315-0f29-4098-ba7a-6a418ebf5a8a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_StrategicScienceAndTechnologiesDLimitedLiabilityCompanyAndStrategicScienceTechnologiesLimitedLiabilityCompanyMember_3c5b684d-cf45-4df0-8162-80ed3ccab31c" xlink:href="dare-20201231.xsd#dare_StrategicScienceAndTechnologiesDLimitedLiabilityCompanyAndStrategicScienceTechnologiesLimitedLiabilityCompanyMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_bf5f4056-bbf5-434f-91e6-cf3b82525db5" xlink:to="loc_dare_StrategicScienceAndTechnologiesDLimitedLiabilityCompanyAndStrategicScienceTechnologiesLimitedLiabilityCompanyMember_3c5b684d-cf45-4df0-8162-80ed3ccab31c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AdarePharmaceuticalsMember_d7f8df41-9f67-4888-b904-4f45742d17f7" xlink:href="dare-20201231.xsd#dare_AdarePharmaceuticalsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_bf5f4056-bbf5-434f-91e6-cf3b82525db5" xlink:to="loc_dare_AdarePharmaceuticalsMember_d7f8df41-9f67-4888-b904-4f45742d17f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis_d079f16a-0647-42f3-a740-c268ed7d0bf3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_171a2c06-b018-4f43-bcdd-dd6b44da1c5f" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis_d079f16a-0647-42f3-a740-c268ed7d0bf3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_ac975910-e774-465b-86c2-983e03153ea7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis_d079f16a-0647-42f3-a740-c268ed7d0bf3" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_ac975910-e774-465b-86c2-983e03153ea7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ADVATecAgreementMember_ffed7e6c-010f-4407-91eb-c4a8c62fd6cf" xlink:href="dare-20201231.xsd#dare_ADVATecAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_ac975910-e774-465b-86c2-983e03153ea7" xlink:to="loc_dare_ADVATecAgreementMember_ffed7e6c-010f-4407-91eb-c4a8c62fd6cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ClinicalAndRegulatoryMilestonesMember_6c021f8f-69fd-4bc1-9f78-4c94c50a8751" xlink:href="dare-20201231.xsd#dare_ClinicalAndRegulatoryMilestonesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_ac975910-e774-465b-86c2-983e03153ea7" xlink:to="loc_dare_ClinicalAndRegulatoryMilestonesMember_6c021f8f-69fd-4bc1-9f78-4c94c50a8751" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_SalesMilestonesMember_f2cc34ad-d8d9-4fae-9f70-d01b1e6febe2" xlink:href="dare-20201231.xsd#dare_SalesMilestonesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_ac975910-e774-465b-86c2-983e03153ea7" xlink:to="loc_dare_SalesMilestonesMember_f2cc34ad-d8d9-4fae-9f70-d01b1e6febe2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContingentConsiderationByTypeAxis_f042ac17-f524-45dc-830d-c6816e8fcabf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContingentConsiderationByTypeAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_171a2c06-b018-4f43-bcdd-dd6b44da1c5f" xlink:to="loc_us-gaap_ContingentConsiderationByTypeAxis_f042ac17-f524-45dc-830d-c6816e8fcabf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContingentConsiderationTypeDomain_3b1499a6-11da-4e8e-88eb-2d509ea87197" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContingentConsiderationTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationByTypeAxis_f042ac17-f524-45dc-830d-c6816e8fcabf" xlink:to="loc_us-gaap_ContingentConsiderationTypeDomain_3b1499a6-11da-4e8e-88eb-2d509ea87197" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponAchievementOfSpecifiedDevelopmentAndRegulatoryMilestonesMember_5fedbaee-9c32-4dd5-9a1b-623d543fd129" xlink:href="dare-20201231.xsd#dare_UponAchievementOfSpecifiedDevelopmentAndRegulatoryMilestonesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ContingentConsiderationTypeDomain_3b1499a6-11da-4e8e-88eb-2d509ea87197" xlink:to="loc_dare_UponAchievementOfSpecifiedDevelopmentAndRegulatoryMilestonesMember_5fedbaee-9c32-4dd5-9a1b-623d543fd129" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalizedCostsOfUnprovedPropertiesExcludedFromAmortizationByPropertyOrProjectAxis_8b3574ab-8ad0-4823-b65a-e9694585fab0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CapitalizedCostsOfUnprovedPropertiesExcludedFromAmortizationByPropertyOrProjectAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_171a2c06-b018-4f43-bcdd-dd6b44da1c5f" xlink:to="loc_us-gaap_CapitalizedCostsOfUnprovedPropertiesExcludedFromAmortizationByPropertyOrProjectAxis_8b3574ab-8ad0-4823-b65a-e9694585fab0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProjectMember_55be4830-bfd3-4dd0-802e-0f5bca1f41a0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProjectMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CapitalizedCostsOfUnprovedPropertiesExcludedFromAmortizationByPropertyOrProjectAxis_8b3574ab-8ad0-4823-b65a-e9694585fab0" xlink:to="loc_us-gaap_ProjectMember_55be4830-bfd3-4dd0-802e-0f5bca1f41a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponAchievementOfSpecifiedDevelopmentAndRegulatoryMilestonesMember_f0b999fc-6219-46ba-9595-c85cbbfc1dfe" xlink:href="dare-20201231.xsd#dare_UponAchievementOfSpecifiedDevelopmentAndRegulatoryMilestonesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProjectMember_55be4830-bfd3-4dd0-802e-0f5bca1f41a0" xlink:to="loc_dare_UponAchievementOfSpecifiedDevelopmentAndRegulatoryMilestonesMember_f0b999fc-6219-46ba-9595-c85cbbfc1dfe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UponReachingCertainWorldwideNetSalesMilestonesMember_d189f11b-3a17-4de0-84b3-dae1473f4228" xlink:href="dare-20201231.xsd#dare_UponReachingCertainWorldwideNetSalesMilestonesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProjectMember_55be4830-bfd3-4dd0-802e-0f5bca1f41a0" xlink:to="loc_dare_UponReachingCertainWorldwideNetSalesMilestonesMember_d189f11b-3a17-4de0-84b3-dae1473f4228" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_1652de0a-b7f0-4052-b1ad-d9c87b7d74dc" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_171a2c06-b018-4f43-bcdd-dd6b44da1c5f" xlink:to="loc_srt_RangeAxis_1652de0a-b7f0-4052-b1ad-d9c87b7d74dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_cfa0f30a-2499-44ff-a616-8d24f9368038" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_1652de0a-b7f0-4052-b1ad-d9c87b7d74dc" xlink:to="loc_srt_RangeMember_cfa0f30a-2499-44ff-a616-8d24f9368038" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_f3c8b152-9b70-4d56-a7a6-e54cfe44668e" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_cfa0f30a-2499-44ff-a616-8d24f9368038" xlink:to="loc_srt_MaximumMember_f3c8b152-9b70-4d56-a7a6-e54cfe44668e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_aa39d0c2-7ebf-4481-9145-cb2f5d8536df" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_cfa0f30a-2499-44ff-a616-8d24f9368038" xlink:to="loc_srt_MinimumMember_aa39d0c2-7ebf-4481-9145-cb2f5d8536df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_94b3f069-f97c-4afc-a528-0357a9323a23" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_171a2c06-b018-4f43-bcdd-dd6b44da1c5f" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_94b3f069-f97c-4afc-a528-0357a9323a23" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_f0347830-ff27-45f8-a4fd-ffab2234129d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_94b3f069-f97c-4afc-a528-0357a9323a23" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_f0347830-ff27-45f8-a4fd-ffab2234129d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MicrochipsBiotechInc.Member_f38101de-809e-4eac-94de-281ae194c568" xlink:href="dare-20201231.xsd#dare_MicrochipsBiotechInc.Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_f0347830-ff27-45f8-a4fd-ffab2234129d" xlink:to="loc_dare_MicrochipsBiotechInc.Member_f38101de-809e-4eac-94de-281ae194c568" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_99f11bae-5779-4dbe-9602-b986d261b6b6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_171a2c06-b018-4f43-bcdd-dd6b44da1c5f" xlink:to="loc_us-gaap_StatementClassOfStockAxis_99f11bae-5779-4dbe-9602-b986d261b6b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_f47d5055-2b3f-428c-9bb0-1fd2fff579a2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_99f11bae-5779-4dbe-9602-b986d261b6b6" xlink:to="loc_us-gaap_ClassOfStockDomain_f47d5055-2b3f-428c-9bb0-1fd2fff579a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_532a0e28-4f32-4102-8691-7e2043be8b56" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_f47d5055-2b3f-428c-9bb0-1fd2fff579a2" xlink:to="loc_us-gaap_CommonStockMember_532a0e28-4f32-4102-8691-7e2043be8b56" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_171a2c06-b018-4f43-bcdd-dd6b44da1c5f" xlink:to="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UpfrontLicenseFeePaid_cecfbb93-483f-47e6-abdc-20e05675091f" xlink:href="dare-20201231.xsd#dare_UpfrontLicenseFeePaid"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_UpfrontLicenseFeePaid_cecfbb93-483f-47e6-abdc-20e05675091f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_b9d5982a-a254-44d2-834b-3a3c7e15824b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_b9d5982a-a254-44d2-834b-3a3c7e15824b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MilestonePaymentsContingentAmount_6ab9bddb-d59e-4971-ae6e-aeab9d752321" xlink:href="dare-20201231.xsd#dare_MilestonePaymentsContingentAmount"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_MilestonePaymentsContingentAmount_6ab9bddb-d59e-4971-ae6e-aeab9d752321" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseFee_6bc431c7-c3ea-4eb8-8020-59b2de242a19" xlink:href="dare-20201231.xsd#dare_LicenseFee"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_LicenseFee_6bc431c7-c3ea-4eb8-8020-59b2de242a19" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseFeeToBePaidUponContingency_27973c74-cb36-4cf9-9b47-692433e582fd" xlink:href="dare-20201231.xsd#dare_LicenseFeeToBePaidUponContingency"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_LicenseFeeToBePaidUponContingency_27973c74-cb36-4cf9-9b47-692433e582fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ResearchAndDevelopmentMilestonePayment_dfd909ae-39e7-4d10-9055-4059e8e273a7" xlink:href="dare-20201231.xsd#dare_ResearchAndDevelopmentMilestonePayment"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_ResearchAndDevelopmentMilestonePayment_dfd909ae-39e7-4d10-9055-4059e8e273a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AssetAcquisitionContingentConsideration_0281cd94-e10a-44dc-9601-4702ce76f810" xlink:href="dare-20201231.xsd#dare_AssetAcquisitionContingentConsideration"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_AssetAcquisitionContingentConsideration_0281cd94-e10a-44dc-9601-4702ce76f810" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseAgreementTerminationPeriodicDiscontinuedSaleOfProduct_cb83d26d-66da-4b3e-a705-c8997ac6a78f" xlink:href="dare-20201231.xsd#dare_LicenseAgreementTerminationPeriodicDiscontinuedSaleOfProduct"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_LicenseAgreementTerminationPeriodicDiscontinuedSaleOfProduct_cb83d26d-66da-4b3e-a705-c8997ac6a78f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseAgreementTerminationPeriodDueToPerformanceFailure_62273144-de97-4d31-9a07-09235939f46e" xlink:href="dare-20201231.xsd#dare_LicenseAgreementTerminationPeriodDueToPerformanceFailure"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_LicenseAgreementTerminationPeriodDueToPerformanceFailure_62273144-de97-4d31-9a07-09235939f46e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LicenseAgreementNoticePeriodOfTermination_dd3c3cf1-7a46-469a-af77-073df2b96bad" xlink:href="dare-20201231.xsd#dare_LicenseAgreementNoticePeriodOfTermination"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_LicenseAgreementNoticePeriodOfTermination_dd3c3cf1-7a46-469a-af77-073df2b96bad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PercentageOfRoyaltyRate_0465bd97-0f18-456f-bc54-79b58bd24fe6" xlink:href="dare-20201231.xsd#dare_PercentageOfRoyaltyRate"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_PercentageOfRoyaltyRate_0465bd97-0f18-456f-bc54-79b58bd24fe6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PercentageOfRightsToInventionsByEmployeesUnderLicenseAgreement_5af216aa-e474-4bc7-9022-bb6bd33e51a3" xlink:href="dare-20201231.xsd#dare_PercentageOfRightsToInventionsByEmployeesUnderLicenseAgreement"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_PercentageOfRightsToInventionsByEmployeesUnderLicenseAgreement_5af216aa-e474-4bc7-9022-bb6bd33e51a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PotentialAnnualLicenseMaintenanceFeePaymentsInYearOne_b8f7dbc8-a452-4558-b576-36c9c73f4117" xlink:href="dare-20201231.xsd#dare_PotentialAnnualLicenseMaintenanceFeePaymentsInYearOne"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_PotentialAnnualLicenseMaintenanceFeePaymentsInYearOne_b8f7dbc8-a452-4558-b576-36c9c73f4117" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PotentialAnnualLicenseMaintenanceFeePaymentsThereafter_45b6409b-5303-4eec-9b69-0c10201ba2bf" xlink:href="dare-20201231.xsd#dare_PotentialAnnualLicenseMaintenanceFeePaymentsThereafter"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_PotentialAnnualLicenseMaintenanceFeePaymentsThereafter_45b6409b-5303-4eec-9b69-0c10201ba2bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MaximumPotentialMilestonePayments_f8eff2f0-3079-4533-b484-aa8d9e222dd2" xlink:href="dare-20201231.xsd#dare_MaximumPotentialMilestonePayments"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_MaximumPotentialMilestonePayments_f8eff2f0-3079-4533-b484-aa8d9e222dd2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_CommencementPeriodForStageTwoUponAchievementOfStageOne_7726015d-ee67-4976-b2c1-922708cbed11" xlink:href="dare-20201231.xsd#dare_CommencementPeriodForStageTwoUponAchievementOfStageOne"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_CommencementPeriodForStageTwoUponAchievementOfStageOne_7726015d-ee67-4976-b2c1-922708cbed11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_b3bd823d-64cb-4533-b9f9-ccaa250c4070" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_b3bd823d-64cb-4533-b9f9-ccaa250c4070" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AssetAcquisitionContingentConsiderationCurrent_849763ca-a208-4fa9-8361-f1590933d20b" xlink:href="dare-20201231.xsd#dare_AssetAcquisitionContingentConsiderationCurrent"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_7962effd-5bf2-4d34-a2fd-4f9995ee704b" xlink:to="loc_dare_AssetAcquisitionContingentConsiderationCurrent_849763ca-a208-4fa9-8361-f1590933d20b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/Acquisition" xlink:type="simple" xlink:href="dare-20201231.xsd#Acquisition"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/Acquisition" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_13cd8a7e-0a52-4efb-9454-13538d017159" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationDisclosureTextBlock_8b3647f6-361c-4042-af75-3eb6106b9ee3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_13cd8a7e-0a52-4efb-9454-13538d017159" xlink:to="loc_us-gaap_BusinessCombinationDisclosureTextBlock_8b3647f6-361c-4042-af75-3eb6106b9ee3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/AcquisitionAdditionalInformationDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#AcquisitionAdditionalInformationDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/AcquisitionAdditionalInformationDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationsAbstract_cd054ab0-d9f0-4244-8f9d-6463e5582b17" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ScheduleOfBusinessCombinationReverseMergerTable_89975db9-5694-47e7-ac47-24cc8a163a07" xlink:href="dare-20201231.xsd#dare_ScheduleOfBusinessCombinationReverseMergerTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessCombinationsAbstract_cd054ab0-d9f0-4244-8f9d-6463e5582b17" xlink:to="loc_dare_ScheduleOfBusinessCombinationReverseMergerTable_89975db9-5694-47e7-ac47-24cc8a163a07" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_86cb87dd-812f-40dd-8942-893589989f71" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_ScheduleOfBusinessCombinationReverseMergerTable_89975db9-5694-47e7-ac47-24cc8a163a07" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_86cb87dd-812f-40dd-8942-893589989f71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_216f10e7-7fae-4234-ba41-7446c776571b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_86cb87dd-812f-40dd-8942-893589989f71" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_216f10e7-7fae-4234-ba41-7446c776571b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MicrochipsBiotechInc.Member_d7ecdbb0-3038-454b-a7da-083b59e6678a" xlink:href="dare-20201231.xsd#dare_MicrochipsBiotechInc.Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_216f10e7-7fae-4234-ba41-7446c776571b" xlink:to="loc_dare_MicrochipsBiotechInc.Member_d7ecdbb0-3038-454b-a7da-083b59e6678a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_6ebea928-6cd1-48a3-af94-77d7c74b7951" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_ScheduleOfBusinessCombinationReverseMergerTable_89975db9-5694-47e7-ac47-24cc8a163a07" xlink:to="loc_us-gaap_StatementClassOfStockAxis_6ebea928-6cd1-48a3-af94-77d7c74b7951" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_79c4c2c7-5d1f-4c63-8ebc-e6f54f37ecf1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_6ebea928-6cd1-48a3-af94-77d7c74b7951" xlink:to="loc_us-gaap_ClassOfStockDomain_79c4c2c7-5d1f-4c63-8ebc-e6f54f37ecf1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_abd5bd4e-1438-4402-aa2d-8f5c680dcfcf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_79c4c2c7-5d1f-4c63-8ebc-e6f54f37ecf1" xlink:to="loc_us-gaap_CommonStockMember_abd5bd4e-1438-4402-aa2d-8f5c680dcfcf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_341506c2-35cf-424f-b5dc-83227e55d23f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_ScheduleOfBusinessCombinationReverseMergerTable_89975db9-5694-47e7-ac47-24cc8a163a07" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_341506c2-35cf-424f-b5dc-83227e55d23f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_8a6562f9-373c-4959-ae8b-3f6fead2e7fe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_341506c2-35cf-424f-b5dc-83227e55d23f" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_8a6562f9-373c-4959-ae8b-3f6fead2e7fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_837d51b3-24d0-4cba-8e59-371392a4d2e5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_8a6562f9-373c-4959-ae8b-3f6fead2e7fe" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_837d51b3-24d0-4cba-8e59-371392a4d2e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_BusinessCombinationReverseMergerLineItems_7660e19a-fa3b-4710-954e-1eed65c764a6" xlink:href="dare-20201231.xsd#dare_BusinessCombinationReverseMergerLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_ScheduleOfBusinessCombinationReverseMergerTable_89975db9-5694-47e7-ac47-24cc8a163a07" xlink:to="loc_dare_BusinessCombinationReverseMergerLineItems_7660e19a-fa3b-4710-954e-1eed65c764a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_a7983a30-155c-43e4-b910-260f9e4df4e0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_BusinessCombinationReverseMergerLineItems_7660e19a-fa3b-4710-954e-1eed65c764a6" xlink:to="loc_us-gaap_BusinessAcquisitionEquityInterestsIssuedOrIssuableNumberOfSharesIssued_a7983a30-155c-43e4-b910-260f9e4df4e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssigned_424b6eb7-88aa-487d-8866-620b86d10157" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssigned"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_BusinessCombinationReverseMergerLineItems_7660e19a-fa3b-4710-954e-1eed65c764a6" xlink:to="loc_us-gaap_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssigned_424b6eb7-88aa-487d-8866-620b86d10157" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionSharePrice_8a56ef8c-13ae-4c5f-82db-4e9357766c1a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionSharePrice"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_BusinessCombinationReverseMergerLineItems_7660e19a-fa3b-4710-954e-1eed65c764a6" xlink:to="loc_us-gaap_BusinessAcquisitionSharePrice_8a56ef8c-13ae-4c5f-82db-4e9357766c1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_BusinessCombinationReverseMergerRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_2a0da29d-684c-46f1-ad7e-07e313352d29" xlink:href="dare-20201231.xsd#dare_BusinessCombinationReverseMergerRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_BusinessCombinationReverseMergerLineItems_7660e19a-fa3b-4710-954e-1eed65c764a6" xlink:to="loc_dare_BusinessCombinationReverseMergerRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_2a0da29d-684c-46f1-ad7e-07e313352d29" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_3b626b4c-50a2-46bd-835a-4ab76405721b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_BusinessCombinationReverseMergerLineItems_7660e19a-fa3b-4710-954e-1eed65c764a6" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_3b626b4c-50a2-46bd-835a-4ab76405721b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/PrepaidExpenses" xlink:type="simple" xlink:href="dare-20201231.xsd#PrepaidExpenses"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/PrepaidExpenses" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_b71fb3f2-24b6-4a4e-a111-02f56b8de2f6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCurrentAssetsTextBlock_cf05ad6e-5978-44d2-9bc2-e6b89806b7eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherCurrentAssetsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_b71fb3f2-24b6-4a4e-a111-02f56b8de2f6" xlink:to="loc_us-gaap_OtherCurrentAssetsTextBlock_cf05ad6e-5978-44d2-9bc2-e6b89806b7eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/PrepaidExpensesTables" xlink:type="simple" xlink:href="dare-20201231.xsd#PrepaidExpensesTables"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/PrepaidExpensesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_92d617cf-5ba2-4667-a824-f709e8a21395" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureTextBlock_2fc94064-3748-46c0-8824-8ef53271f210" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_92d617cf-5ba2-4667-a824-f709e8a21395" xlink:to="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureTextBlock_2fc94064-3748-46c0-8824-8ef53271f210" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/PrepaidExpensesDetails" xlink:type="simple" xlink:href="dare-20201231.xsd#PrepaidExpensesDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/PrepaidExpensesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_405082bd-e955-4d71-9286-7ac1c9784f53" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PrepaidClinicalExpense_fb486dc1-a304-4d26-872b-a4e0fe345082" xlink:href="dare-20201231.xsd#dare_PrepaidClinicalExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_405082bd-e955-4d71-9286-7ac1c9784f53" xlink:to="loc_dare_PrepaidClinicalExpense_fb486dc1-a304-4d26-872b-a4e0fe345082" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidInsurance_50c6ad9c-9789-425b-80fc-abeb94dae9ad" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PrepaidInsurance"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_405082bd-e955-4d71-9286-7ac1c9784f53" xlink:to="loc_us-gaap_PrepaidInsurance_50c6ad9c-9789-425b-80fc-abeb94dae9ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PrepaidProfessionalExpense_e3e20b15-bbab-4420-a863-a1caf780ab8b" xlink:href="dare-20201231.xsd#dare_PrepaidProfessionalExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_405082bd-e955-4d71-9286-7ac1c9784f53" xlink:to="loc_dare_PrepaidProfessionalExpense_e3e20b15-bbab-4420-a863-a1caf780ab8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseCurrent_46996d94-5fc9-4548-bbd8-bb0216966e79" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PrepaidExpenseCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredCostsCapitalizedPrepaidAndOtherAssetsDisclosureAbstract_405082bd-e955-4d71-9286-7ac1c9784f53" xlink:to="loc_us-gaap_PrepaidExpenseCurrent_46996d94-5fc9-4548-bbd8-bb0216966e79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/OtherNonCurrentAssets" xlink:type="simple" xlink:href="dare-20201231.xsd#OtherNonCurrentAssets"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/OtherNonCurrentAssets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrentDisclosureAbstract_243dc300-2ef4-41c8-9ab1-863c499a815f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAssetsNoncurrentDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_OtherAssetsNoncurrentDisclosureTextBlock_b7d2c912-3ec3-4b6e-b0e5-14ed3a80829e" xlink:href="dare-20201231.xsd#dare_OtherAssetsNoncurrentDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherAssetsNoncurrentDisclosureAbstract_243dc300-2ef4-41c8-9ab1-863c499a815f" xlink:to="loc_dare_OtherAssetsNoncurrentDisclosureTextBlock_b7d2c912-3ec3-4b6e-b0e5-14ed3a80829e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/OtherNonCurrentAssetsTables" xlink:type="simple" xlink:href="dare-20201231.xsd#OtherNonCurrentAssetsTables"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/OtherNonCurrentAssetsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrentDisclosureAbstract_c5896952-6bef-4b96-875d-b908110882de" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAssetsNoncurrentDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfOtherAssetsNoncurrentTextBlock_a4b475c0-0b36-4282-9a7c-3fea71e4c684" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfOtherAssetsNoncurrentTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherAssetsNoncurrentDisclosureAbstract_c5896952-6bef-4b96-875d-b908110882de" xlink:to="loc_us-gaap_ScheduleOfOtherAssetsNoncurrentTextBlock_a4b475c0-0b36-4282-9a7c-3fea71e4c684" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/OtherNonCurrentAssetsScheduleofOtherNonCurrentAssetsDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#OtherNonCurrentAssetsScheduleofOtherNonCurrentAssetsDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/OtherNonCurrentAssetsScheduleofOtherNonCurrentAssetsDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrentDisclosureAbstract_7574085d-95f0-44ff-963a-96c112eff4fe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAssetsNoncurrentDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PrepaidInsuranceNoncurrent_f0208948-c2e4-4d6c-9d25-f71caff100de" xlink:href="dare-20201231.xsd#dare_PrepaidInsuranceNoncurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherAssetsNoncurrentDisclosureAbstract_7574085d-95f0-44ff-963a-96c112eff4fe" xlink:to="loc_dare_PrepaidInsuranceNoncurrent_f0208948-c2e4-4d6c-9d25-f71caff100de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositsAssetsNoncurrent_1f1065ba-a037-4dd7-9a05-c84483341a3c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DepositsAssetsNoncurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherAssetsNoncurrentDisclosureAbstract_7574085d-95f0-44ff-963a-96c112eff4fe" xlink:to="loc_us-gaap_DepositsAssetsNoncurrent_1f1065ba-a037-4dd7-9a05-c84483341a3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_OperatingLeaseRightOfUseAssetNoncurrent_82c7cb79-a535-4811-8040-293b4df16e9b" xlink:href="dare-20201231.xsd#dare_OperatingLeaseRightOfUseAssetNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherAssetsNoncurrentDisclosureAbstract_7574085d-95f0-44ff-963a-96c112eff4fe" xlink:to="loc_dare_OperatingLeaseRightOfUseAssetNoncurrent_82c7cb79-a535-4811-8040-293b4df16e9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_0352c50e-c327-4e9d-8533-a44f4ab0fce9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherAssetsNoncurrentDisclosureAbstract_7574085d-95f0-44ff-963a-96c112eff4fe" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_0352c50e-c327-4e9d-8533-a44f4ab0fce9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/AccruedExpenses" xlink:type="simple" xlink:href="dare-20201231.xsd#AccruedExpenses"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/AccruedExpenses" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_226554f3-8693-4c2a-82a4-cce9c1f008a0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PayablesAndAccrualsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_b1321f54-a8b0-41f6-9a89-8d48e12b5d7d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_226554f3-8693-4c2a-82a4-cce9c1f008a0" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_b1321f54-a8b0-41f6-9a89-8d48e12b5d7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/AccruedExpensesTables" xlink:type="simple" xlink:href="dare-20201231.xsd#AccruedExpensesTables"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/AccruedExpensesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_8cfc268b-933a-4bf9-bff1-ca471673d8be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PayablesAndAccrualsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock_1b140cd4-df9a-4511-b4a6-c54043053552" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_8cfc268b-933a-4bf9-bff1-ca471673d8be" xlink:to="loc_us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock_1b140cd4-df9a-4511-b4a6-c54043053552" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/AccruedExpensesScheduleofAccountsPayableandAccruedExpensesDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#AccruedExpensesScheduleofAccountsPayableandAccruedExpensesDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/AccruedExpensesScheduleofAccountsPayableandAccruedExpensesDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_40fbcecf-a3f5-48dd-9c3f-2abcca4ce8b3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PayablesAndAccrualsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_87e5b700-ce7b-4ffb-b7a2-46c7167e6f1e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_40fbcecf-a3f5-48dd-9c3f-2abcca4ce8b3" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_87e5b700-ce7b-4ffb-b7a2-46c7167e6f1e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedProfessionalFeesCurrent_68991934-8186-4cec-b2e8-238f39f1923d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccruedProfessionalFeesCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_40fbcecf-a3f5-48dd-9c3f-2abcca4ce8b3" xlink:to="loc_us-gaap_AccruedProfessionalFeesCurrent_68991934-8186-4cec-b2e8-238f39f1923d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AccruedLicenseExpense_16b6efe9-d535-44d4-a684-1936c19d7be9" xlink:href="dare-20201231.xsd#dare_AccruedLicenseExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_40fbcecf-a3f5-48dd-9c3f-2abcca4ce8b3" xlink:to="loc_dare_AccruedLicenseExpense_16b6efe9-d535-44d4-a684-1936c19d7be9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_e43ea104-b43c-42d8-b1ba-aa4276421d29" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAccruedLiabilitiesCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_40fbcecf-a3f5-48dd-9c3f-2abcca4ce8b3" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_e43ea104-b43c-42d8-b1ba-aa4276421d29" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_f74d673a-f6e9-4479-bfd3-a92791b7b78f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_40fbcecf-a3f5-48dd-9c3f-2abcca4ce8b3" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_f74d673a-f6e9-4479-bfd3-a92791b7b78f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/IncomeTaxes" xlink:type="simple" xlink:href="dare-20201231.xsd#IncomeTaxes"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/IncomeTaxes" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_a97d1415-5b5b-4404-881f-86e59571b3c6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock_7e00dbb4-a5cf-4362-8fa3-117a3aa75552" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_a97d1415-5b5b-4404-881f-86e59571b3c6" xlink:to="loc_us-gaap_IncomeTaxDisclosureTextBlock_7e00dbb4-a5cf-4362-8fa3-117a3aa75552" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/IncomeTaxesTables" xlink:type="simple" xlink:href="dare-20201231.xsd#IncomeTaxesTables"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/IncomeTaxesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_c53800be-a928-4bd0-a66d-6af49edfe01f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock_2a5f0717-4309-4759-b587-022f8274bf66" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_c53800be-a928-4bd0-a66d-6af49edfe01f" xlink:to="loc_us-gaap_ScheduleOfComponentsOfIncomeTaxExpenseBenefitTableTextBlock_2a5f0717-4309-4759-b587-022f8274bf66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_d50e26d9-d608-4f2f-b9d1-b2a10b860045" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_c53800be-a928-4bd0-a66d-6af49edfe01f" xlink:to="loc_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_d50e26d9-d608-4f2f-b9d1-b2a10b860045" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_5e4faa16-fbb1-46e0-8423-d5ec0519ffba" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_c53800be-a928-4bd0-a66d-6af49edfe01f" xlink:to="loc_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_5e4faa16-fbb1-46e0-8423-d5ec0519ffba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfUnrecognizedTaxBenefitsRollForwardTableTextBlock_84e3e679-6750-4076-9c8c-dbe04873b803" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfUnrecognizedTaxBenefitsRollForwardTableTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_c53800be-a928-4bd0-a66d-6af49edfe01f" xlink:to="loc_us-gaap_ScheduleOfUnrecognizedTaxBenefitsRollForwardTableTextBlock_84e3e679-6750-4076-9c8c-dbe04873b803" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/IncomeTaxesSummaryofComponentsofLossfromContinuingOperationsBeforeProvisionforIncomeTaxesDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#IncomeTaxesSummaryofComponentsofLossfromContinuingOperationsBeforeProvisionforIncomeTaxesDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/IncomeTaxesSummaryofComponentsofLossfromContinuingOperationsBeforeProvisionforIncomeTaxesDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_5a617735-b0fe-45af-98d4-2802b23cd25f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_84228cc7-7e62-42af-9d0a-e47e5529173c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_5a617735-b0fe-45af-98d4-2802b23cd25f" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_84228cc7-7e62-42af-9d0a-e47e5529173c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_0594292d-4bcf-4009-b5b0-52e712a457fb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_5a617735-b0fe-45af-98d4-2802b23cd25f" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_0594292d-4bcf-4009-b5b0-52e712a457fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_c8b0ffa4-4d44-49d4-b3de-2884b72ad64f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_5a617735-b0fe-45af-98d4-2802b23cd25f" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_c8b0ffa4-4d44-49d4-b3de-2884b72ad64f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/IncomeTaxesReconciliationofProvisionforIncomeTaxesBenefitandAmountComputedbyApplyingUSFederalIncomeTaxRateDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#IncomeTaxesReconciliationofProvisionforIncomeTaxesBenefitandAmountComputedbyApplyingUSFederalIncomeTaxRateDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/IncomeTaxesReconciliationofProvisionforIncomeTaxesBenefitandAmountComputedbyApplyingUSFederalIncomeTaxRateDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_7cce0eee-8b9f-4b52-a5fb-b3a177313f1a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_7232c896-f06d-41fe-8c8d-af8cb738b57d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7cce0eee-8b9f-4b52-a5fb-b3a177313f1a" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_7232c896-f06d-41fe-8c8d-af8cb738b57d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes_0161ee84-5164-4e32-8ede-a55e232a8daa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7cce0eee-8b9f-4b52-a5fb-b3a177313f1a" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes_0161ee84-5164-4e32-8ede-a55e232a8daa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_EffectiveIncomeTaxRateReconciliationPermanentDifferences_5286287a-f5c8-43de-844b-234a0cecdda9" xlink:href="dare-20201231.xsd#dare_EffectiveIncomeTaxRateReconciliationPermanentDifferences"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7cce0eee-8b9f-4b52-a5fb-b3a177313f1a" xlink:to="loc_dare_EffectiveIncomeTaxRateReconciliationPermanentDifferences_5286287a-f5c8-43de-844b-234a0cecdda9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch_36b0c8b3-5e0b-45d2-9b3b-a01c0dff53fe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7cce0eee-8b9f-4b52-a5fb-b3a177313f1a" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch_36b0c8b3-5e0b-45d2-9b3b-a01c0dff53fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost_941d2ef5-41bf-4a25-bf30-ba91275c9490" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7cce0eee-8b9f-4b52-a5fb-b3a177313f1a" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost_941d2ef5-41bf-4a25-bf30-ba91275c9490" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsOther_97f7c48f-5cc0-472c-b3a7-d67d9cdcd85c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsOther"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7cce0eee-8b9f-4b52-a5fb-b3a177313f1a" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsOther_97f7c48f-5cc0-472c-b3a7-d67d9cdcd85c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance_301c053b-ff95-43a6-bf4d-5546af897004" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7cce0eee-8b9f-4b52-a5fb-b3a177313f1a" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance_301c053b-ff95-43a6-bf4d-5546af897004" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_8f17ecf4-e429-414a-b3a6-db4d1d3ad219" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperations"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7cce0eee-8b9f-4b52-a5fb-b3a177313f1a" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_8f17ecf4-e429-414a-b3a6-db4d1d3ad219" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/IncomeTaxesSummaryofMajorComponentsofCompanysDeferredTaxAssetsDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#IncomeTaxesSummaryofMajorComponentsofCompanysDeferredTaxAssetsDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/IncomeTaxesSummaryofMajorComponentsofCompanysDeferredTaxAssetsDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_7bb096bb-4589-4adc-8243-58ad40b11b1e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_fac68583-23b3-4749-88e4-9eea933a9e66" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwards"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7bb096bb-4589-4adc-8243-58ad40b11b1e" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_fac68583-23b3-4749-88e4-9eea933a9e66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch_3b8f1ae0-dbc2-4066-b650-275cc86bcb59" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7bb096bb-4589-4adc-8243-58ad40b11b1e" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch_3b8f1ae0-dbc2-4066-b650-275cc86bcb59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_DeferredTaxAssetsCapitalizedResearchAndDevelopmentCost_67586346-49df-4421-8f05-f5e5664d3d52" xlink:href="dare-20201231.xsd#dare_DeferredTaxAssetsCapitalizedResearchAndDevelopmentCost"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7bb096bb-4589-4adc-8243-58ad40b11b1e" xlink:to="loc_dare_DeferredTaxAssetsCapitalizedResearchAndDevelopmentCost_67586346-49df-4421-8f05-f5e5664d3d52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsOther_29a1e962-43ae-471a-be74-70a992b4a06e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsOther"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7bb096bb-4589-4adc-8243-58ad40b11b1e" xlink:to="loc_us-gaap_DeferredTaxAssetsOther_29a1e962-43ae-471a-be74-70a992b4a06e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_ee0b1015-bad5-4ee5-b583-8a63ae7a5b2e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7bb096bb-4589-4adc-8243-58ad40b11b1e" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_ee0b1015-bad5-4ee5-b583-8a63ae7a5b2e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsGross_bfe7da3d-966a-4166-87bb-706633d10307" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsGross"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7bb096bb-4589-4adc-8243-58ad40b11b1e" xlink:to="loc_us-gaap_DeferredTaxAssetsGross_bfe7da3d-966a-4166-87bb-706633d10307" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowance_faab2a01-c6f1-4ded-b81b-4e99534ff305" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsValuationAllowance"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7bb096bb-4589-4adc-8243-58ad40b11b1e" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowance_faab2a01-c6f1-4ded-b81b-4e99534ff305" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsNet_4424dc08-0b57-4463-a1fb-a342b004d0ea" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsNet"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_7bb096bb-4589-4adc-8243-58ad40b11b1e" xlink:to="loc_us-gaap_DeferredTaxAssetsNet_4424dc08-0b57-4463-a1fb-a342b004d0ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/IncomeTaxesSummaryofReconciliationofBeginningandEndingAmountofUncertainTaxBenefitsDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#IncomeTaxesSummaryofReconciliationofBeginningandEndingAmountofUncertainTaxBenefitsDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/IncomeTaxesSummaryofReconciliationofBeginningandEndingAmountofUncertainTaxBenefitsDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_b7229dd1-7584-4df8-b33c-5c4835e58312" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_2db04bcd-7e6c-4ae0-a94f-40611161015b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_b7229dd1-7584-4df8-b33c-5c4835e58312" xlink:to="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_2db04bcd-7e6c-4ae0-a94f-40611161015b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefits_56bc4fa3-22c0-47dd-a9af-215eaca4c730" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefits"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_2db04bcd-7e6c-4ae0-a94f-40611161015b" xlink:to="loc_us-gaap_UnrecognizedTaxBenefits_56bc4fa3-22c0-47dd-a9af-215eaca4c730" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions_3757432d-3a06-4a6e-905f-2c1cb0c7f423" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_2db04bcd-7e6c-4ae0-a94f-40611161015b" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions_3757432d-3a06-4a6e-905f-2c1cb0c7f423" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions_e8fe5a13-c69d-47d7-b4b6-2c1219d12f50" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_2db04bcd-7e6c-4ae0-a94f-40611161015b" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions_e8fe5a13-c69d-47d7-b4b6-2c1219d12f50" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions_9eed9359-acff-4dd7-9b30-0eecf4fa8afb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_2db04bcd-7e6c-4ae0-a94f-40611161015b" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions_9eed9359-acff-4dd7-9b30-0eecf4fa8afb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefits_9307e14c-a52a-4dae-a82a-9ae1943b4b37" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefits"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReconciliationOfUnrecognizedTaxBenefitsExcludingAmountsPertainingToExaminedTaxReturnsRollForward_2db04bcd-7e6c-4ae0-a94f-40611161015b" xlink:to="loc_us-gaap_UnrecognizedTaxBenefits_9307e14c-a52a-4dae-a82a-9ae1943b4b37" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/IncomeTaxesAdditionalInformationDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#IncomeTaxesAdditionalInformationDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/IncomeTaxesAdditionalInformationDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_4a7fb4bc-2ba8-4382-8afe-9a91c2bffc9e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLossCarryforwardsTable_0f26da67-41bc-4f58-8adb-cbe62aa776ef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLossCarryforwardsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_4a7fb4bc-2ba8-4382-8afe-9a91c2bffc9e" xlink:to="loc_us-gaap_OperatingLossCarryforwardsTable_0f26da67-41bc-4f58-8adb-cbe62aa776ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxAuthorityAxis_8623f3bd-94a2-4b36-820e-5fbc221869fb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxAuthorityAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsTable_0f26da67-41bc-4f58-8adb-cbe62aa776ef" xlink:to="loc_us-gaap_IncomeTaxAuthorityAxis_8623f3bd-94a2-4b36-820e-5fbc221869fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxAuthorityDomain_02e12b2c-3393-477e-a22b-41422d1f2435" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxAuthorityDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityAxis_8623f3bd-94a2-4b36-820e-5fbc221869fb" xlink:to="loc_us-gaap_IncomeTaxAuthorityDomain_02e12b2c-3393-477e-a22b-41422d1f2435" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DomesticCountryMember_e9c9c416-efeb-497c-9b4c-d59f0a028b87" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DomesticCountryMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_02e12b2c-3393-477e-a22b-41422d1f2435" xlink:to="loc_us-gaap_DomesticCountryMember_e9c9c416-efeb-497c-9b4c-d59f0a028b87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StateAndLocalJurisdictionMember_c7f5e288-c15d-462f-934f-d21b99feb9bc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StateAndLocalJurisdictionMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_02e12b2c-3393-477e-a22b-41422d1f2435" xlink:to="loc_us-gaap_StateAndLocalJurisdictionMember_c7f5e288-c15d-462f-934f-d21b99feb9bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TaxCreditCarryforwardAxis_d7e7d42b-7481-4435-9fcb-2f1697f0ac03" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TaxCreditCarryforwardAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsTable_0f26da67-41bc-4f58-8adb-cbe62aa776ef" xlink:to="loc_us-gaap_TaxCreditCarryforwardAxis_d7e7d42b-7481-4435-9fcb-2f1697f0ac03" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TaxCreditCarryforwardNameDomain_87c6d179-0519-4004-92c8-067bd98bf0a6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TaxCreditCarryforwardNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TaxCreditCarryforwardAxis_d7e7d42b-7481-4435-9fcb-2f1697f0ac03" xlink:to="loc_us-gaap_TaxCreditCarryforwardNameDomain_87c6d179-0519-4004-92c8-067bd98bf0a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchMember_2e9aaff1-3d1b-47b7-ac1c-0d858b6cd778" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResearchMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TaxCreditCarryforwardNameDomain_87c6d179-0519-4004-92c8-067bd98bf0a6" xlink:to="loc_us-gaap_ResearchMember_2e9aaff1-3d1b-47b7-ac1c-0d858b6cd778" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLossCarryforwardsLineItems_f198850c-2b31-4ad4-8a54-1e867a171ac7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLossCarryforwardsLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsTable_0f26da67-41bc-4f58-8adb-cbe62aa776ef" xlink:to="loc_us-gaap_OperatingLossCarryforwardsLineItems_f198850c-2b31-4ad4-8a54-1e867a171ac7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowance_26efb983-214f-49d8-892e-c0f96a63882a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsValuationAllowance"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_f198850c-2b31-4ad4-8a54-1e867a171ac7" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowance_26efb983-214f-49d8-892e-c0f96a63882a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount_94c214a1-2f04-46c7-abae-d2cd4d5f23f0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_f198850c-2b31-4ad4-8a54-1e867a171ac7" xlink:to="loc_us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount_94c214a1-2f04-46c7-abae-d2cd4d5f23f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLossCarryforwards_ee8f6f1f-2667-4323-ac56-4289f3b3bd9c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLossCarryforwards"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_f198850c-2b31-4ad4-8a54-1e867a171ac7" xlink:to="loc_us-gaap_OperatingLossCarryforwards_ee8f6f1f-2667-4323-ac56-4289f3b3bd9c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration_4f9c5ae9-abcc-4164-936a-6ba3c53c9799" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_f198850c-2b31-4ad4-8a54-1e867a171ac7" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration_4f9c5ae9-abcc-4164-936a-6ba3c53c9799" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_OperatingLossCarryforwardsExpirationPeriod_a635348a-92be-4013-b75b-bc8613d58e70" xlink:href="dare-20201231.xsd#dare_OperatingLossCarryforwardsExpirationPeriod"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_f198850c-2b31-4ad4-8a54-1e867a171ac7" xlink:to="loc_dare_OperatingLossCarryforwardsExpirationPeriod_a635348a-92be-4013-b75b-bc8613d58e70" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsNotSubjectToExpiration_c3bb26bc-ba75-4c82-9d23-5d9a1ddc94d5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsNotSubjectToExpiration"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_f198850c-2b31-4ad4-8a54-1e867a171ac7" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsNotSubjectToExpiration_c3bb26bc-ba75-4c82-9d23-5d9a1ddc94d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TaxCreditCarryforwardAmount_618ee62c-f18d-4ede-9104-086e37cb7cb8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TaxCreditCarryforwardAmount"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_f198850c-2b31-4ad4-8a54-1e867a171ac7" xlink:to="loc_us-gaap_TaxCreditCarryforwardAmount_618ee62c-f18d-4ede-9104-086e37cb7cb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_TaxCreditCarryforwardExpirationPeriod_24e933aa-e704-47fc-a4fd-ef8064427849" xlink:href="dare-20201231.xsd#dare_TaxCreditCarryforwardExpirationPeriod"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_f198850c-2b31-4ad4-8a54-1e867a171ac7" xlink:to="loc_dare_TaxCreditCarryforwardExpirationPeriod_24e933aa-e704-47fc-a4fd-ef8064427849" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefits_5c8244e8-dfb8-4704-aac9-5d04db7800f9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefits"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_f198850c-2b31-4ad4-8a54-1e867a171ac7" xlink:to="loc_us-gaap_UnrecognizedTaxBenefits_5c8244e8-dfb8-4704-aac9-5d04db7800f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued_ba530a21-47f4-4e5f-ad91-2929a1681940" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_f198850c-2b31-4ad4-8a54-1e867a171ac7" xlink:to="loc_us-gaap_UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued_ba530a21-47f4-4e5f-ad91-2929a1681940" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UnremittedEarnings_843e99d8-2d77-4e10-87cb-95263776f493" xlink:href="dare-20201231.xsd#dare_UnremittedEarnings"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingLossCarryforwardsLineItems_f198850c-2b31-4ad4-8a54-1e867a171ac7" xlink:to="loc_dare_UnremittedEarnings_843e99d8-2d77-4e10-87cb-95263776f493" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockholdersEquity" xlink:type="simple" xlink:href="dare-20201231.xsd#StockholdersEquity"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockholdersEquity" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_b108de60-af9f-4399-876b-df0ff8da51b3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_3bb9a168-ae44-41f5-82a0-6d3868ee90a6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_b108de60-af9f-4399-876b-df0ff8da51b3" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_3bb9a168-ae44-41f5-82a0-6d3868ee90a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockholdersEquityTables" xlink:type="simple" xlink:href="dare-20201231.xsd#StockholdersEquityTables"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockholdersEquityTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_91c17d5b-c0c1-4db7-8168-b7c217fa7244" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock_1235ec01-efba-4bcb-9169-3dfebb2fc9a3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_91c17d5b-c0c1-4db7-8168-b7c217fa7244" xlink:to="loc_us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock_1235ec01-efba-4bcb-9169-3dfebb2fc9a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ScheduleOfCommonStockReservedForFutureIssuanceTableTextBlock_7ab3a9d2-c1d4-4407-ae38-bc40b57c6fba" xlink:href="dare-20201231.xsd#dare_ScheduleOfCommonStockReservedForFutureIssuanceTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_91c17d5b-c0c1-4db7-8168-b7c217fa7244" xlink:to="loc_dare_ScheduleOfCommonStockReservedForFutureIssuanceTableTextBlock_7ab3a9d2-c1d4-4407-ae38-bc40b57c6fba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockholdersEquityAdditionalInformationDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#StockholdersEquityAdditionalInformationDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockholdersEquityAdditionalInformationDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_63f11313-6041-4b65-bdaf-438189d5e248" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_6f0d0ed1-9192-4f75-abee-d7c2334fb655" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_63f11313-6041-4b65-bdaf-438189d5e248" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_6f0d0ed1-9192-4f75-abee-d7c2334fb655" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_1dc7d738-3a9b-4721-8e95-2e1f23aa8303" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_6f0d0ed1-9192-4f75-abee-d7c2334fb655" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_1dc7d738-3a9b-4721-8e95-2e1f23aa8303" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfAdoptionMember_baf79938-2bf2-49b8-a30e-fce3f33d43ec" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_TypeOfAdoptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_1dc7d738-3a9b-4721-8e95-2e1f23aa8303" xlink:to="loc_us-gaap_TypeOfAdoptionMember_baf79938-2bf2-49b8-a30e-fce3f33d43ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingStandardsUpdate201711Member_ad882387-dbd3-4bcf-b12a-59cbaace4ec7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountingStandardsUpdate201711Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfAdoptionMember_baf79938-2bf2-49b8-a30e-fce3f33d43ec" xlink:to="loc_us-gaap_AccountingStandardsUpdate201711Member_ad882387-dbd3-4bcf-b12a-59cbaace4ec7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_de9c328a-3810-4260-a0ab-0f67e4fa6037" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_6f0d0ed1-9192-4f75-abee-d7c2334fb655" xlink:to="loc_srt_RangeAxis_de9c328a-3810-4260-a0ab-0f67e4fa6037" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_c50d3c59-9880-4a74-889b-82da7f15d032" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_de9c328a-3810-4260-a0ab-0f67e4fa6037" xlink:to="loc_srt_RangeMember_c50d3c59-9880-4a74-889b-82da7f15d032" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_2ec7aaf1-4d25-426c-8d36-eca20acf331e" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_c50d3c59-9880-4a74-889b-82da7f15d032" xlink:to="loc_srt_MaximumMember_2ec7aaf1-4d25-426c-8d36-eca20acf331e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_b9e19c35-a45c-4226-8c82-4db3d67d0150" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_c50d3c59-9880-4a74-889b-82da7f15d032" xlink:to="loc_srt_MinimumMember_b9e19c35-a45c-4226-8c82-4db3d67d0150" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_713160f1-bd99-4d8d-a20c-b61cd6f70368" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_6f0d0ed1-9192-4f75-abee-d7c2334fb655" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_713160f1-bd99-4d8d-a20c-b61cd6f70368" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_9df668b9-744e-46d5-9d9c-7a6f8704e12e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_713160f1-bd99-4d8d-a20c-b61cd6f70368" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_9df668b9-744e-46d5-9d9c-7a6f8704e12e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AtTheMarketSalesAgreementMember_a8fcaa94-dec4-4e79-9900-1ba0ff6d909f" xlink:href="dare-20201231.xsd#dare_AtTheMarketSalesAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_9df668b9-744e-46d5-9d9c-7a6f8704e12e" xlink:to="loc_dare_AtTheMarketSalesAgreementMember_a8fcaa94-dec4-4e79-9900-1ba0ff6d909f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PublicStockOfferingMember_adacbb57-7c37-4daf-9989-7121bb808760" xlink:href="dare-20201231.xsd#dare_PublicStockOfferingMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_9df668b9-744e-46d5-9d9c-7a6f8704e12e" xlink:to="loc_dare_PublicStockOfferingMember_adacbb57-7c37-4daf-9989-7121bb808760" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OverAllotmentOptionMember_9f1b3eeb-2658-4718-b1ec-8301ee4543fd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OverAllotmentOptionMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_9df668b9-744e-46d5-9d9c-7a6f8704e12e" xlink:to="loc_us-gaap_OverAllotmentOptionMember_9f1b3eeb-2658-4718-b1ec-8301ee4543fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PurchaseAgreementMember_9f68dccb-75fb-4ba6-ad87-0d9fdeb395b2" xlink:href="dare-20201231.xsd#dare_PurchaseAgreementMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_9df668b9-744e-46d5-9d9c-7a6f8704e12e" xlink:to="loc_dare_PurchaseAgreementMember_9f68dccb-75fb-4ba6-ad87-0d9fdeb395b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LegalEntityAxis_c451ba60-18a0-4116-9cf9-c9dfeb641cc6" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LegalEntityAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_6f0d0ed1-9192-4f75-abee-d7c2334fb655" xlink:to="loc_dei_LegalEntityAxis_c451ba60-18a0-4116-9cf9-c9dfeb641cc6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityDomain_9d6dad65-178f-4fa0-ba0e-6f54acf8fc01" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_LegalEntityAxis_c451ba60-18a0-4116-9cf9-c9dfeb641cc6" xlink:to="loc_dei_EntityDomain_9d6dad65-178f-4fa0-ba0e-6f54acf8fc01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LincolnParkMember_39c5b93d-ab5a-40d9-8769-d083dd97b53e" xlink:href="dare-20201231.xsd#dare_LincolnParkMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_9d6dad65-178f-4fa0-ba0e-6f54acf8fc01" xlink:to="loc_dare_LincolnParkMember_39c5b93d-ab5a-40d9-8769-d083dd97b53e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_72bbc5f6-bc43-4541-b40c-d57593aae3c0" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_6f0d0ed1-9192-4f75-abee-d7c2334fb655" xlink:to="loc_srt_CounterpartyNameAxis_72bbc5f6-bc43-4541-b40c-d57593aae3c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_bf1f427f-63bc-407b-9e25-431224b9b885" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_72bbc5f6-bc43-4541-b40c-d57593aae3c0" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_bf1f427f-63bc-407b-9e25-431224b9b885" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LincolnParkMember_572f56cd-68ea-4d9c-b567-2aa24e3d68b4" xlink:href="dare-20201231.xsd#dare_LincolnParkMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_bf1f427f-63bc-407b-9e25-431224b9b885" xlink:to="loc_dare_LincolnParkMember_572f56cd-68ea-4d9c-b567-2aa24e3d68b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_635a9f6c-4372-4ffb-8798-e1d408c90977" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_6f0d0ed1-9192-4f75-abee-d7c2334fb655" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_635a9f6c-4372-4ffb-8798-e1d408c90977" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_8decca54-51ef-4936-a986-28bda3266f70" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_635a9f6c-4372-4ffb-8798-e1d408c90977" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_8decca54-51ef-4936-a986-28bda3266f70" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_257831e8-13f3-48f9-b23c-684b6fb55011" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_8decca54-51ef-4936-a986-28bda3266f70" xlink:to="loc_us-gaap_SubsequentEventMember_257831e8-13f3-48f9-b23c-684b6fb55011" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_6f0d0ed1-9192-4f75-abee-d7c2334fb655" xlink:to="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PercentageOfAggregateCommission_46b0ae91-a580-4c6f-8dd7-ff5a79defdca" xlink:href="dare-20201231.xsd#dare_PercentageOfAggregateCommission"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_PercentageOfAggregateCommission_46b0ae91-a580-4c6f-8dd7-ff5a79defdca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_21a3dcb1-cf7c-46e1-ac29-8f564479207c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_21a3dcb1-cf7c-46e1-ac29-8f564479207c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_fe4e9284-7f7d-4c74-a369-46c5ffef9e52" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_fe4e9284-7f7d-4c74-a369-46c5ffef9e52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_OfferingExpenses_5984e539-92c8-40e6-9168-24de2f8f7ced" xlink:href="dare-20201231.xsd#dare_OfferingExpenses"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_OfferingExpenses_5984e539-92c8-40e6-9168-24de2f8f7ced" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockPricePerShare_fa3fcedc-8295-4c77-89e6-15aa64f2ebfe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SaleOfStockPricePerShare"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_SaleOfStockPricePerShare_fa3fcedc-8295-4c77-89e6-15aa64f2ebfe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UnderwritersOptionToPurchaseAdditionalSharesOfCommonStockPeriod_5d8283b1-a1ff-4d0e-8d17-606ba1fa41bc" xlink:href="dare-20201231.xsd#dare_UnderwritersOptionToPurchaseAdditionalSharesOfCommonStockPeriod"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_UnderwritersOptionToPurchaseAdditionalSharesOfCommonStockPeriod_5d8283b1-a1ff-4d0e-8d17-606ba1fa41bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_UnderwritersOptionToPurchaseAdditionalShares_e84a0264-96e6-4323-bd54-cf0a0749acb0" xlink:href="dare-20201231.xsd#dare_UnderwritersOptionToPurchaseAdditionalShares"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_UnderwritersOptionToPurchaseAdditionalShares_e84a0264-96e6-4323-bd54-cf0a0749acb0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_GrossProceedsFromOfferingOfCommonStockAndWarrants_aca66508-c5f9-49bf-a9c4-789f2f0da043" xlink:href="dare-20201231.xsd#dare_GrossProceedsFromOfferingOfCommonStockAndWarrants"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_GrossProceedsFromOfferingOfCommonStockAndWarrants_aca66508-c5f9-49bf-a9c4-789f2f0da043" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_0159c752-4f06-4807-b4ba-9584a150afc5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SaleOfStockConsiderationReceivedOnTransaction"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_0159c752-4f06-4807-b4ba-9584a150afc5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PurchaseObligation_a77b0413-76b9-45bf-a90d-3a475d36347a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PurchaseObligation"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_PurchaseObligation_a77b0413-76b9-45bf-a90d-3a475d36347a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_SaleofStockMaximumAmountRegistered_c065856d-cd18-4769-9611-e0f2464363cd" xlink:href="dare-20201231.xsd#dare_SaleofStockMaximumAmountRegistered"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_SaleofStockMaximumAmountRegistered_c065856d-cd18-4769-9611-e0f2464363cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredOfferingCosts_9abd67be-4586-40a9-be2a-af29033b7af0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredOfferingCosts"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_DeferredOfferingCosts_9abd67be-4586-40a9-be2a-af29033b7af0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_DeferredOfferingCostsUnamortizedPortion_e87a0ff5-11e8-4484-8478-4b48ce683d98" xlink:href="dare-20201231.xsd#dare_DeferredOfferingCostsUnamortizedPortion"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_DeferredOfferingCostsUnamortizedPortion_e87a0ff5-11e8-4484-8478-4b48ce683d98" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_71450954-e4bd-4930-815d-3768cd274bd9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_71450954-e4bd-4930-815d-3768cd274bd9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfStockIssuanceCosts_293fd48d-5916-430f-b42f-e0d21be6770e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsOfStockIssuanceCosts"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_PaymentsOfStockIssuanceCosts_293fd48d-5916-430f-b42f-e0d21be6770e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_RegularRepurchaseCommonStockIssuable_282549ef-bf50-42ac-9e59-d6b2c592bc3a" xlink:href="dare-20201231.xsd#dare_RegularRepurchaseCommonStockIssuable"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_RegularRepurchaseCommonStockIssuable_282549ef-bf50-42ac-9e59-d6b2c592bc3a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_RegularPurchaseCommonStockIssuableIncreaseAmount_8e41b5f0-e638-477f-a29b-d8340400dc02" xlink:href="dare-20201231.xsd#dare_RegularPurchaseCommonStockIssuableIncreaseAmount"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_RegularPurchaseCommonStockIssuableIncreaseAmount_8e41b5f0-e638-477f-a29b-d8340400dc02" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_RegularPurchaseCommonStockIssuableMaximumAmount_19c0fd47-be3d-4376-bfb9-3075b2d30d2d" xlink:href="dare-20201231.xsd#dare_RegularPurchaseCommonStockIssuableMaximumAmount"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_RegularPurchaseCommonStockIssuableMaximumAmount_19c0fd47-be3d-4376-bfb9-3075b2d30d2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_CommonStockExchangeCap_f99e7e5c-8c6b-4835-93ad-669742087f5c" xlink:href="dare-20201231.xsd#dare_CommonStockExchangeCap"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_CommonStockExchangeCap_f99e7e5c-8c6b-4835-93ad-669742087f5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharePrice_3a8d866d-cc41-48fe-8907-c46c47f1e5a0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharePrice"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_SharePrice_3a8d866d-cc41-48fe-8907-c46c47f1e5a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_CommonStockExchangeCapPercentage_ddf2f572-9523-419c-8468-2465b03d2679" xlink:href="dare-20201231.xsd#dare_CommonStockExchangeCapPercentage"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_CommonStockExchangeCapPercentage_ddf2f572-9523-419c-8468-2465b03d2679" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_d283e81f-a2c2-4423-9025-5498fd6009a4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_d283e81f-a2c2-4423-9025-5498fd6009a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_EstimatedFairValueOfWarrantsRecordedInEquity_0eaaf83a-3d8f-4f34-a7e7-8a9611faf19d" xlink:href="dare-20201231.xsd#dare_EstimatedFairValueOfWarrantsRecordedInEquity"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_EstimatedFairValueOfWarrantsRecordedInEquity_0eaaf83a-3d8f-4f34-a7e7-8a9611faf19d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantExercisePriceDecrease_82b462ec-2c22-4c69-9f4d-6ed36c7b14b8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WarrantExercisePriceDecrease"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_WarrantExercisePriceDecrease_82b462ec-2c22-4c69-9f4d-6ed36c7b14b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_02ff56fe-f51b-499e-8e4f-22353434a749" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_WarrantDownRoundFeatureIncreaseDecreaseInEquityAmount_02ff56fe-f51b-499e-8e4f-22353434a749" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_NumberOfCommonStockWarrantsExercised_e6be51e1-3ecc-4e37-817a-3b9ff0133c9c" xlink:href="dare-20201231.xsd#dare_NumberOfCommonStockWarrantsExercised"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_dare_NumberOfCommonStockWarrantsExercised_e6be51e1-3ecc-4e37-817a-3b9ff0133c9c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromWarrantExercises_5c7ad0d2-8d28-477d-8bac-d45af9de32a3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromWarrantExercises"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_ProceedsFromWarrantExercises_5c7ad0d2-8d28-477d-8bac-d45af9de32a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_f2204a0d-fb1f-41ec-aabf-8e3bb2dd3e90" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_f2204a0d-fb1f-41ec-aabf-8e3bb2dd3e90" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_be568a11-d42d-4e84-907f-d14427e1f081" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_be568a11-d42d-4e84-907f-d14427e1f081" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_73d851c0-4585-4f9a-acce-6100f97dd44c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockSharesAuthorized"/>
    <link:presentationArc order="30" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_73d851c0-4585-4f9a-acce-6100f97dd44c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_4c5e50bb-706a-455a-8d37-299e07c0827c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockParOrStatedValuePerShare"/>
    <link:presentationArc order="31" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_4c5e50bb-706a-455a-8d37-299e07c0827c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_d7f4d0fe-a082-4dd7-9f95-aaffd5af3475" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesIssued"/>
    <link:presentationArc order="32" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_CommonStockSharesIssued_d7f4d0fe-a082-4dd7-9f95-aaffd5af3475" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_6855bc0e-587d-4799-9452-c64461c9ebb4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="33" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_6855bc0e-587d-4799-9452-c64461c9ebb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_bdbf07ac-645c-472f-af11-95acdb34afc5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PreferredStockSharesOutstanding"/>
    <link:presentationArc order="34" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_fd245240-5eef-4640-82f9-967d5373a26c" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_bdbf07ac-645c-472f-af11-95acdb34afc5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockholdersEquityScheduleofCommonStockWarrantsOutstandingDetails" xlink:type="simple" xlink:href="dare-20201231.xsd#StockholdersEquityScheduleofCommonStockWarrantsOutstandingDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockholdersEquityScheduleofCommonStockWarrantsOutstandingDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_5ce1adc4-313e-4dd9-ab55-430c3a06902e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_715ad449-71a4-4c98-bb52-04d4e6334a6d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_5ce1adc4-313e-4dd9-ab55-430c3a06902e" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_715ad449-71a4-4c98-bb52-04d4e6334a6d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_86d2fed6-a9fc-48b6-a81b-2bb5f409d9d6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_715ad449-71a4-4c98-bb52-04d4e6334a6d" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_86d2fed6-a9fc-48b6-a81b-2bb5f409d9d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_419ff6c9-633c-40fd-93c4-b871779277fd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_86d2fed6-a9fc-48b6-a81b-2bb5f409d9d6" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_419ff6c9-633c-40fd-93c4-b871779277fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_WarrantsExpiringOnDecemberOneTwoThousandTwentyOneMember_9c5a40a9-1af5-4023-afc1-002480468937" xlink:href="dare-20201231.xsd#dare_WarrantsExpiringOnDecemberOneTwoThousandTwentyOneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_419ff6c9-633c-40fd-93c4-b871779277fd" xlink:to="loc_dare_WarrantsExpiringOnDecemberOneTwoThousandTwentyOneMember_9c5a40a9-1af5-4023-afc1-002480468937" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_WarrantsExpiringOnDecemberSixTwoThousandTwentyOneMember_cd0a3793-a728-47a2-8b6c-75aff9e1c858" xlink:href="dare-20201231.xsd#dare_WarrantsExpiringOnDecemberSixTwoThousandTwentyOneMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_419ff6c9-633c-40fd-93c4-b871779277fd" xlink:to="loc_dare_WarrantsExpiringOnDecemberSixTwoThousandTwentyOneMember_cd0a3793-a728-47a2-8b6c-75aff9e1c858" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_WarrantsExpiringOnAprilFourTwoThousandTwentySixMember_8ba36ca8-5476-4ecb-ad24-5c638b251d97" xlink:href="dare-20201231.xsd#dare_WarrantsExpiringOnAprilFourTwoThousandTwentySixMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_419ff6c9-633c-40fd-93c4-b871779277fd" xlink:to="loc_dare_WarrantsExpiringOnAprilFourTwoThousandTwentySixMember_8ba36ca8-5476-4ecb-ad24-5c638b251d97" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_WarrantsExpiringOnFebruaryFifteenTwoThousandTwentyThreeMember_e7093b57-f031-460f-bd3d-f1b2a5ab1c31" xlink:href="dare-20201231.xsd#dare_WarrantsExpiringOnFebruaryFifteenTwoThousandTwentyThreeMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_419ff6c9-633c-40fd-93c4-b871779277fd" xlink:to="loc_dare_WarrantsExpiringOnFebruaryFifteenTwoThousandTwentyThreeMember_e7093b57-f031-460f-bd3d-f1b2a5ab1c31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_3af353d1-4ca4-4f03-bdce-a28922924c7b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_715ad449-71a4-4c98-bb52-04d4e6334a6d" xlink:to="loc_us-gaap_ClassOfStockLineItems_3af353d1-4ca4-4f03-bdce-a28922924c7b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightOutstanding_c7004a0b-e4f6-4332-bab5-fe85e3fc67fb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfWarrantOrRightOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_3af353d1-4ca4-4f03-bdce-a28922924c7b" xlink:to="loc_us-gaap_ClassOfWarrantOrRightOutstanding_c7004a0b-e4f6-4332-bab5-fe85e3fc67fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_dfa32ab8-6f3c-455d-ae6c-e987f6f6218a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_3af353d1-4ca4-4f03-bdce-a28922924c7b" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_dfa32ab8-6f3c-455d-ae6c-e987f6f6218a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockholdersEquitySummaryofCommonStockReservedforFutureIssuanceDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#StockholdersEquitySummaryofCommonStockReservedforFutureIssuanceDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockholdersEquitySummaryofCommonStockReservedforFutureIssuanceDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_da46b1aa-3172-4e2f-a63e-b305439f5491" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_40e2a73f-3558-4911-88b1-296593040e15" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_da46b1aa-3172-4e2f-a63e-b305439f5491" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_40e2a73f-3558-4911-88b1-296593040e15" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_58eb3e5c-cedf-4278-af4c-c8ccb7eb067b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_40e2a73f-3558-4911-88b1-296593040e15" xlink:to="loc_us-gaap_PlanNameAxis_58eb3e5c-cedf-4278-af4c-c8ccb7eb067b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_32713526-d7fb-43e3-8474-41798f616ea7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_58eb3e5c-cedf-4278-af4c-c8ccb7eb067b" xlink:to="loc_us-gaap_PlanNameDomain_32713526-d7fb-43e3-8474-41798f616ea7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember_6cc75322-8f5a-4ee4-9cd3-cc6d12d4694f" xlink:href="dare-20201231.xsd#dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_32713526-d7fb-43e3-8474-41798f616ea7" xlink:to="loc_dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember_6cc75322-8f5a-4ee4-9cd3-cc6d12d4694f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_1ab7c62d-5055-406e-b269-5e56358a1f0c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_40e2a73f-3558-4911-88b1-296593040e15" xlink:to="loc_us-gaap_AwardTypeAxis_1ab7c62d-5055-406e-b269-5e56358a1f0c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_7fd3321b-4cb3-4b87-a3b4-695ad1bbd7c8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_1ab7c62d-5055-406e-b269-5e56358a1f0c" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_7fd3321b-4cb3-4b87-a3b4-695ad1bbd7c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ExerciseOfWarrantsOutstandingMember_d50490ae-2c16-4ed1-97a9-b090a4cb6f3d" xlink:href="dare-20201231.xsd#dare_ExerciseOfWarrantsOutstandingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_7fd3321b-4cb3-4b87-a3b4-695ad1bbd7c8" xlink:to="loc_dare_ExerciseOfWarrantsOutstandingMember_d50490ae-2c16-4ed1-97a9-b090a4cb6f3d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ExerciseOfOptionsOutstandingMember_bdeba6b9-066a-46b2-ae66-62bb6f8622b8" xlink:href="dare-20201231.xsd#dare_ExerciseOfOptionsOutstandingMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_7fd3321b-4cb3-4b87-a3b4-695ad1bbd7c8" xlink:to="loc_dare_ExerciseOfOptionsOutstandingMember_bdeba6b9-066a-46b2-ae66-62bb6f8622b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_fe7c9fdf-4d15-42db-bd7a-54be875bcea5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_7fd3321b-4cb3-4b87-a3b4-695ad1bbd7c8" xlink:to="loc_us-gaap_EmployeeStockOptionMember_fe7c9fdf-4d15-42db-bd7a-54be875bcea5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_02927f83-6472-4a4a-9128-319666b01eb9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_40e2a73f-3558-4911-88b1-296593040e15" xlink:to="loc_us-gaap_ClassOfStockLineItems_02927f83-6472-4a4a-9128-319666b01eb9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_aa628eef-52a0-426f-90bd-9699c0a9e2ab" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_02927f83-6472-4a4a-9128-319666b01eb9" xlink:to="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_aa628eef-52a0-426f-90bd-9699c0a9e2ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockBasedCompensation" xlink:type="simple" xlink:href="dare-20201231.xsd#StockBasedCompensation"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockBasedCompensation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_90d3fce9-4379-4ae9-a2a9-ee93ec219198" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_4894bdc7-bf21-4e13-9485-26f8ae27417b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_90d3fce9-4379-4ae9-a2a9-ee93ec219198" xlink:to="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_4894bdc7-bf21-4e13-9485-26f8ae27417b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockbasedCompensationTables" xlink:type="simple" xlink:href="dare-20201231.xsd#StockbasedCompensationTables"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockbasedCompensationTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_8c6c8260-d26d-400d-b1d9-7b9cca1305fc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_2202ff14-f238-4775-ab0d-34eb56afe639" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_8c6c8260-d26d-400d-b1d9-7b9cca1305fc" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_2202ff14-f238-4775-ab0d-34eb56afe639" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_4845eac6-2242-4d93-8ccd-6475c7ef0b41" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_8c6c8260-d26d-400d-b1d9-7b9cca1305fc" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_4845eac6-2242-4d93-8ccd-6475c7ef0b41" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_9b96a0c6-f965-4713-b61a-12ab0d89b59a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_8c6c8260-d26d-400d-b1d9-7b9cca1305fc" xlink:to="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_9b96a0c6-f965-4713-b61a-12ab0d89b59a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockbasedcompensationAdditionalInformationDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#StockbasedcompensationAdditionalInformationDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockbasedcompensationAdditionalInformationDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_99d2db60-ce1a-4ce2-8d6a-76ad44c59515" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_59becff3-723c-43ae-8f8a-3c68373ef038" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_99d2db60-ce1a-4ce2-8d6a-76ad44c59515" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_59becff3-723c-43ae-8f8a-3c68373ef038" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_6bb6fc82-98ba-4376-8b44-67b8fa6ccba3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_59becff3-723c-43ae-8f8a-3c68373ef038" xlink:to="loc_us-gaap_PlanNameAxis_6bb6fc82-98ba-4376-8b44-67b8fa6ccba3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_d67f75f8-2641-41d7-9bf7-fa7cb5115592" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_6bb6fc82-98ba-4376-8b44-67b8fa6ccba3" xlink:to="loc_us-gaap_PlanNameDomain_d67f75f8-2641-41d7-9bf7-fa7cb5115592" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_TwoThousandAndFifteenStockIncentivePlanMember_8fe3ba1c-3036-4eb5-a8a2-f3e56f2bd5a5" xlink:href="dare-20201231.xsd#dare_TwoThousandAndFifteenStockIncentivePlanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_d67f75f8-2641-41d7-9bf7-fa7cb5115592" xlink:to="loc_dare_TwoThousandAndFifteenStockIncentivePlanMember_8fe3ba1c-3036-4eb5-a8a2-f3e56f2bd5a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_TwoThousandAndFourteenEmployeeStockPurchasePlanMember_b2e4aecd-08ad-49d5-9716-898f6e698cf8" xlink:href="dare-20201231.xsd#dare_TwoThousandAndFourteenEmployeeStockPurchasePlanMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_d67f75f8-2641-41d7-9bf7-fa7cb5115592" xlink:to="loc_dare_TwoThousandAndFourteenEmployeeStockPurchasePlanMember_b2e4aecd-08ad-49d5-9716-898f6e698cf8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember_3277baf6-8824-4cc4-b1c3-73a522d63a3c" xlink:href="dare-20201231.xsd#dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_d67f75f8-2641-41d7-9bf7-fa7cb5115592" xlink:to="loc_dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember_3277baf6-8824-4cc4-b1c3-73a522d63a3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_df9a9e64-38c8-4e37-a539-583061459979" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_59becff3-723c-43ae-8f8a-3c68373ef038" xlink:to="loc_us-gaap_AwardTypeAxis_df9a9e64-38c8-4e37-a539-583061459979" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0aea2db5-0337-4c60-870e-7b849cd10521" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_df9a9e64-38c8-4e37-a539-583061459979" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0aea2db5-0337-4c60-870e-7b849cd10521" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_17602a99-7340-4969-8f9b-c92104dbcccf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0aea2db5-0337-4c60-870e-7b849cd10521" xlink:to="loc_us-gaap_EmployeeStockOptionMember_17602a99-7340-4969-8f9b-c92104dbcccf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockMember_837fcd25-6c1b-4a50-8f99-8046fedbe6a9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RestrictedStockMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0aea2db5-0337-4c60-870e-7b849cd10521" xlink:to="loc_us-gaap_RestrictedStockMember_837fcd25-6c1b-4a50-8f99-8046fedbe6a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LegalEntityAxis_5804e1af-3adf-4659-8a92-6d1acee6fa4d" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_LegalEntityAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_59becff3-723c-43ae-8f8a-3c68373ef038" xlink:to="loc_dei_LegalEntityAxis_5804e1af-3adf-4659-8a92-6d1acee6fa4d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityDomain_12ab4839-628b-4b89-bf9e-f91142dec782" xlink:href="https://xbrl.sec.gov/dei/2020/dei-2020-01-31.xsd#dei_EntityDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_LegalEntityAxis_5804e1af-3adf-4659-8a92-6d1acee6fa4d" xlink:to="loc_dei_EntityDomain_12ab4839-628b-4b89-bf9e-f91142dec782" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PrivateDareMember_9438baa1-caf0-4ce7-a1c6-42ae2ea274f2" xlink:href="dare-20201231.xsd#dare_PrivateDareMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_12ab4839-628b-4b89-bf9e-f91142dec782" xlink:to="loc_dare_PrivateDareMember_9438baa1-caf0-4ce7-a1c6-42ae2ea274f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8ac2a69f-536b-40da-b032-81f377765d3d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_59becff3-723c-43ae-8f8a-3c68373ef038" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8ac2a69f-536b-40da-b032-81f377765d3d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_746cd640-0033-4eee-9c4d-92d3362b4146" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8ac2a69f-536b-40da-b032-81f377765d3d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_746cd640-0033-4eee-9c4d-92d3362b4146" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_4a334d84-2356-42f9-8f04-7970ad32eee3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8ac2a69f-536b-40da-b032-81f377765d3d" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_4a334d84-2356-42f9-8f04-7970ad32eee3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_62e4a10e-4586-4518-a4b6-8524672473e9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8ac2a69f-536b-40da-b032-81f377765d3d" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_62e4a10e-4586-4518-a4b6-8524672473e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_bd45aeb5-015f-4ef3-9825-d3c9bf75fe3e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8ac2a69f-536b-40da-b032-81f377765d3d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_bd45aeb5-015f-4ef3-9825-d3c9bf75fe3e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfOutstandingStockMaximum_b3821132-f744-43fd-9eba-8c10e53705e0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfOutstandingStockMaximum"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8ac2a69f-536b-40da-b032-81f377765d3d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfOutstandingStockMaximum_b3821132-f744-43fd-9eba-8c10e53705e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNumberOfSharesPeriodIncreaseDecrease_af9b0bcf-8593-4c11-ad53-c5d645cea877" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNumberOfSharesPeriodIncreaseDecrease"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8ac2a69f-536b-40da-b032-81f377765d3d" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNumberOfSharesPeriodIncreaseDecrease_af9b0bcf-8593-4c11-ad53-c5d645cea877" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_b0d44da2-cf51-4f0c-9776-655316da8bb3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8ac2a69f-536b-40da-b032-81f377765d3d" xlink:to="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_b0d44da2-cf51-4f0c-9776-655316da8bb3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCompensationSharebasedArrangementsLiabilityCurrentAndNoncurrent_1bcda3e4-201b-4543-9365-5e4f28bc0e2b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DeferredCompensationSharebasedArrangementsLiabilityCurrentAndNoncurrent"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8ac2a69f-536b-40da-b032-81f377765d3d" xlink:to="loc_us-gaap_DeferredCompensationSharebasedArrangementsLiabilityCurrentAndNoncurrent_1bcda3e4-201b-4543-9365-5e4f28bc0e2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_WeightedAverageAmortizationPeriod_861c656f-d2bb-462f-b61f-b254f80939a5" xlink:href="dare-20201231.xsd#dare_WeightedAverageAmortizationPeriod"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8ac2a69f-536b-40da-b032-81f377765d3d" xlink:to="loc_dare_WeightedAverageAmortizationPeriod_861c656f-d2bb-462f-b61f-b254f80939a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_447d36a8-a998-4e8a-ac88-637f6e548953" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8ac2a69f-536b-40da-b032-81f377765d3d" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_447d36a8-a998-4e8a-ac88-637f6e548953" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockbasedCompensationSummaryofStockOptionActivityDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#StockbasedCompensationSummaryofStockOptionActivityDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockbasedCompensationSummaryofStockOptionActivityDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_c9090aef-6f4c-41e5-9967-c565dbb7aef7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_a4652f1a-2eb9-4e18-9ee8-13b0c0ce20c5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_c9090aef-6f4c-41e5-9967-c565dbb7aef7" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_a4652f1a-2eb9-4e18-9ee8-13b0c0ce20c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_16105511-ee2d-4750-bbd4-63e92b71f0d2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_a4652f1a-2eb9-4e18-9ee8-13b0c0ce20c5" xlink:to="loc_us-gaap_PlanNameAxis_16105511-ee2d-4750-bbd4-63e92b71f0d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_011859f5-6a2f-4dcd-878e-ecd2e2c253a4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_16105511-ee2d-4750-bbd4-63e92b71f0d2" xlink:to="loc_us-gaap_PlanNameDomain_011859f5-6a2f-4dcd-878e-ecd2e2c253a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember_9f6f2f43-7622-48f7-8dea-1c41055c081a" xlink:href="dare-20201231.xsd#dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_011859f5-6a2f-4dcd-878e-ecd2e2c253a4" xlink:to="loc_dare_AmendedAndRestatedTwoThousandFourteenStockIncentivePlanMember_9f6f2f43-7622-48f7-8dea-1c41055c081a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_30a519dd-d955-4d39-ac21-ce2cd4babb7f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_a4652f1a-2eb9-4e18-9ee8-13b0c0ce20c5" xlink:to="loc_us-gaap_AwardTypeAxis_30a519dd-d955-4d39-ac21-ce2cd4babb7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_359ee56e-f139-41dc-b95b-05c1341dcaf1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_30a519dd-d955-4d39-ac21-ce2cd4babb7f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_359ee56e-f139-41dc-b95b-05c1341dcaf1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_2e75407d-3e43-4602-a5b4-2bb3e20979b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_359ee56e-f139-41dc-b95b-05c1341dcaf1" xlink:to="loc_us-gaap_EmployeeStockOptionMember_2e75407d-3e43-4602-a5b4-2bb3e20979b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7c5256f3-62f4-41ec-8ebb-0e51cacde44a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_a4652f1a-2eb9-4e18-9ee8-13b0c0ce20c5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7c5256f3-62f4-41ec-8ebb-0e51cacde44a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_44834784-ba36-4dff-9181-49d3194d0750" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7c5256f3-62f4-41ec-8ebb-0e51cacde44a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_44834784-ba36-4dff-9181-49d3194d0750" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_29785d00-efa9-4781-9085-092b1a828779" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_44834784-ba36-4dff-9181-49d3194d0750" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_29785d00-efa9-4781-9085-092b1a828779" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_03adfd9d-0799-4ebb-b9cd-a5b9a32a0a00" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_44834784-ba36-4dff-9181-49d3194d0750" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_03adfd9d-0799-4ebb-b9cd-a5b9a32a0a00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_d10c4641-3885-482b-9f18-13843448f2e8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_44834784-ba36-4dff-9181-49d3194d0750" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_d10c4641-3885-482b-9f18-13843448f2e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_8a1a323a-bc44-4aa8-8fbd-cf6ab53ecef0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_44834784-ba36-4dff-9181-49d3194d0750" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_8a1a323a-bc44-4aa8-8fbd-cf6ab53ecef0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_b7c7e20b-db45-4271-85a5-e5050a9a74a7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_44834784-ba36-4dff-9181-49d3194d0750" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_b7c7e20b-db45-4271-85a5-e5050a9a74a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_33522aff-d131-48ec-b1d7-6e30c150e916" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_44834784-ba36-4dff-9181-49d3194d0750" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_33522aff-d131-48ec-b1d7-6e30c150e916" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_36921d19-b89e-4d2c-a26b-18f26bb412d3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7c5256f3-62f4-41ec-8ebb-0e51cacde44a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_36921d19-b89e-4d2c-a26b-18f26bb412d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_16e277f7-805f-4d6a-b1b8-36f5c2fe33c2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7c5256f3-62f4-41ec-8ebb-0e51cacde44a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber_16e277f7-805f-4d6a-b1b8-36f5c2fe33c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_d65d70a1-1800-4b43-a9f2-4acebdd75f04" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7c5256f3-62f4-41ec-8ebb-0e51cacde44a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_d65d70a1-1800-4b43-a9f2-4acebdd75f04" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_4d5269cb-37fe-4ba2-87b5-a37254ba3bbc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_d65d70a1-1800-4b43-a9f2-4acebdd75f04" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_4d5269cb-37fe-4ba2-87b5-a37254ba3bbc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_c95e9940-b11e-47e8-b620-29972c94891e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_d65d70a1-1800-4b43-a9f2-4acebdd75f04" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_c95e9940-b11e-47e8-b620-29972c94891e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_0b1a1e5b-c834-43a7-af54-8492f58b83e9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_d65d70a1-1800-4b43-a9f2-4acebdd75f04" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_0b1a1e5b-c834-43a7-af54-8492f58b83e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice_de8df5e5-1b56-4cfe-b0f5-c1d33e873030" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_d65d70a1-1800-4b43-a9f2-4acebdd75f04" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice_de8df5e5-1b56-4cfe-b0f5-c1d33e873030" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_5a7f85d2-bb26-4a46-a240-dfa1a5f5b455" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_d65d70a1-1800-4b43-a9f2-4acebdd75f04" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_5a7f85d2-bb26-4a46-a240-dfa1a5f5b455" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_a65ce6d1-bd0a-4099-8f68-9e54652535d6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_d65d70a1-1800-4b43-a9f2-4acebdd75f04" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_a65ce6d1-bd0a-4099-8f68-9e54652535d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_73fe96a9-b090-4789-bd9d-30f46048e999" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7c5256f3-62f4-41ec-8ebb-0e51cacde44a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_73fe96a9-b090-4789-bd9d-30f46048e999" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_7ff7b2c2-6786-47ca-ae4a-5d7c1f05b57c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7c5256f3-62f4-41ec-8ebb-0e51cacde44a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_7ff7b2c2-6786-47ca-ae4a-5d7c1f05b57c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTermRollForward_3ac16bc8-df99-4912-95e9-abe98e1dad69" xlink:href="dare-20201231.xsd#dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTermRollForward"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7c5256f3-62f4-41ec-8ebb-0e51cacde44a" xlink:to="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTermRollForward_3ac16bc8-df99-4912-95e9-abe98e1dad69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_b00b2603-ae34-45e1-a3a4-a4da1afafc1f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTermRollForward_3ac16bc8-df99-4912-95e9-abe98e1dad69" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_b00b2603-ae34-45e1-a3a4-a4da1afafc1f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_5db0fdcd-a86d-4ac4-95ad-5e3ac77bd70a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTermRollForward_3ac16bc8-df99-4912-95e9-abe98e1dad69" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_5db0fdcd-a86d-4ac4-95ad-5e3ac77bd70a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1_f9456400-46f8-4669-81f7-7a5e5b0536ec" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTermRollForward_3ac16bc8-df99-4912-95e9-abe98e1dad69" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1_f9456400-46f8-4669-81f7-7a5e5b0536ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingAggregateIntrinsicValueRollForward_9039343f-5d72-4457-96af-2e11308f375b" xlink:href="dare-20201231.xsd#dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingAggregateIntrinsicValueRollForward"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_7c5256f3-62f4-41ec-8ebb-0e51cacde44a" xlink:to="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingAggregateIntrinsicValueRollForward_9039343f-5d72-4457-96af-2e11308f375b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_56850127-1c4a-4fa7-a460-340e10b2b8b7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingAggregateIntrinsicValueRollForward_9039343f-5d72-4457-96af-2e11308f375b" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_56850127-1c4a-4fa7-a460-340e10b2b8b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_de417a78-2f84-450a-adef-14017baa21d2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingAggregateIntrinsicValueRollForward_9039343f-5d72-4457-96af-2e11308f375b" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_de417a78-2f84-450a-adef-14017baa21d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue_99d37fe4-5b52-4a74-8da5-83c3a49fbe10" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingAggregateIntrinsicValueRollForward_9039343f-5d72-4457-96af-2e11308f375b" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue_99d37fe4-5b52-4a74-8da5-83c3a49fbe10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockbasedCompensationCompensationExpenseDetails" xlink:type="simple" xlink:href="dare-20201231.xsd#StockbasedCompensationCompensationExpenseDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockbasedCompensationCompensationExpenseDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_22b7151d-5ab2-45e3-a239-c9a768c8035c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_3dad103e-e827-4bd4-8bb4-5161ef0a6ee2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_22b7151d-5ab2-45e3-a239-c9a768c8035c" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_3dad103e-e827-4bd4-8bb4-5161ef0a6ee2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_4827620f-de25-4b8e-b872-7be30604ef74" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_3dad103e-e827-4bd4-8bb4-5161ef0a6ee2" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_4827620f-de25-4b8e-b872-7be30604ef74" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_b2324fa4-f023-4f21-a151-052d7f4dc076" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_4827620f-de25-4b8e-b872-7be30604ef74" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_b2324fa4-f023-4f21-a151-052d7f4dc076" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_c4960f06-969a-480d-a83f-c7c0e523d5e3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_b2324fa4-f023-4f21-a151-052d7f4dc076" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_c4960f06-969a-480d-a83f-c7c0e523d5e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpenseMember_5fe2340f-a9ef-4ec0-9de6-57f103c51d01" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GeneralAndAdministrativeExpenseMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_b2324fa4-f023-4f21-a151-052d7f4dc076" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpenseMember_5fe2340f-a9ef-4ec0-9de6-57f103c51d01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_c6d35b87-c193-4ee2-94da-188d248aec26" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_3dad103e-e827-4bd4-8bb4-5161ef0a6ee2" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_c6d35b87-c193-4ee2-94da-188d248aec26" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_b07361b9-7cc8-4d15-a2ea-6c211b00d8cc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_c6d35b87-c193-4ee2-94da-188d248aec26" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_b07361b9-7cc8-4d15-a2ea-6c211b00d8cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/StockbasedCompensationSummaryofAssumptionsUsedinBlackScholesOptionPricingModelforStockOptionsGrantedtoEmployeesandNonEmployeeDirectorsDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#StockbasedCompensationSummaryofAssumptionsUsedinBlackScholesOptionPricingModelforStockOptionsGrantedtoEmployeesandNonEmployeeDirectorsDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/StockbasedCompensationSummaryofAssumptionsUsedinBlackScholesOptionPricingModelforStockOptionsGrantedtoEmployeesandNonEmployeeDirectorsDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_f1db8935-9512-4357-b831-ebbd59d23ecd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_b51d36ca-62a6-476f-93d5-c88abe07c8e0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_f1db8935-9512-4357-b831-ebbd59d23ecd" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_b51d36ca-62a6-476f-93d5-c88abe07c8e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_fe8b680a-14c2-4a78-91be-a2e3b21e7644" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_f1db8935-9512-4357-b831-ebbd59d23ecd" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_fe8b680a-14c2-4a78-91be-a2e3b21e7644" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_5d6fc064-e2bb-43de-a9b5-e96c5d73344d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_f1db8935-9512-4357-b831-ebbd59d23ecd" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_5d6fc064-e2bb-43de-a9b5-e96c5d73344d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsForfeitureRate_3c35b642-5880-4ebf-9a58-b13932164466" xlink:href="dare-20201231.xsd#dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsForfeitureRate"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_f1db8935-9512-4357-b831-ebbd59d23ecd" xlink:to="loc_dare_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsForfeitureRate_3c35b642-5880-4ebf-9a58-b13932164466" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_e3bb4839-06db-442f-91ff-6ab65d2a389e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_f1db8935-9512-4357-b831-ebbd59d23ecd" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_e3bb4839-06db-442f-91ff-6ab65d2a389e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_2c4816d4-49f4-41aa-a5c8-110dba992394" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_f1db8935-9512-4357-b831-ebbd59d23ecd" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_2c4816d4-49f4-41aa-a5c8-110dba992394" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/LeasedProperties" xlink:type="simple" xlink:href="dare-20201231.xsd#LeasedProperties"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/LeasedProperties" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_2cf7ad57-70a0-484e-90a9-8158ca431cf9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeasesTextBlock_aea1d23f-b8c5-48c3-bcc4-5632ac0051fe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeasesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_2cf7ad57-70a0-484e-90a9-8158ca431cf9" xlink:to="loc_us-gaap_LesseeOperatingLeasesTextBlock_aea1d23f-b8c5-48c3-bcc4-5632ac0051fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/LeasedPropertiesTables" xlink:type="simple" xlink:href="dare-20201231.xsd#LeasedPropertiesTables"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/LeasedPropertiesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_8efe09b4-09ea-4a7c-8205-800e202ed251" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_3eea5d25-1674-45d2-9c1c-ee42a919f4be" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_8efe09b4-09ea-4a7c-8205-800e202ed251" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_3eea5d25-1674-45d2-9c1c-ee42a919f4be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/LeasedPropertiesAdditionalInformationDetails" xlink:type="simple" xlink:href="dare-20201231.xsd#LeasedPropertiesAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/LeasedPropertiesAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_f48047e4-d752-4570-b0b4-e14df3291989" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionTable_ccb47f5b-78d2-4e35-8655-5f2048d6aa1b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_f48047e4-d752-4570-b0b4-e14df3291989" xlink:to="loc_us-gaap_LesseeLeaseDescriptionTable_ccb47f5b-78d2-4e35-8655-5f2048d6aa1b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_4fc5deb7-90f8-4ec8-91ac-5e5d78426be9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BalanceSheetLocationAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_ccb47f5b-78d2-4e35-8655-5f2048d6aa1b" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_4fc5deb7-90f8-4ec8-91ac-5e5d78426be9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_c6ff8df7-6db0-4035-9780-3834fc8c09c6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BalanceSheetLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_4fc5deb7-90f8-4ec8-91ac-5e5d78426be9" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_c6ff8df7-6db0-4035-9780-3834fc8c09c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCurrentAssetsMember_5b6cd4a9-3da9-46b8-af83-c8b1b6028142" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherCurrentAssetsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_c6ff8df7-6db0-4035-9780-3834fc8c09c6" xlink:to="loc_us-gaap_OtherCurrentAssetsMember_5b6cd4a9-3da9-46b8-af83-c8b1b6028142" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_ccb47f5b-78d2-4e35-8655-5f2048d6aa1b" xlink:to="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetRentableArea_1adcb297-d8f5-4e81-b9d8-1c3bda0aae4d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetRentableArea"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:to="loc_us-gaap_NetRentableArea_1adcb297-d8f5-4e81-b9d8-1c3bda0aae4d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_873f2f9f-de5b-46a3-9353-bc432eb981d7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseRenewalTerm"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:to="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_873f2f9f-de5b-46a3-9353-bc432eb981d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseDiscountRate_83122b17-70d1-454e-ab01-6b16612ecaf3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseDiscountRate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:to="loc_us-gaap_LesseeOperatingLeaseDiscountRate_83122b17-70d1-454e-ab01-6b16612ecaf3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_d36acb83-93aa-4653-a9e2-28e6179844de" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_d36acb83-93aa-4653-a9e2-28e6179844de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAssetStatementOfFinancialPositionExtensibleList_dcd86b5d-393f-4aa4-938a-e84131308f87" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAssetStatementOfFinancialPositionExtensibleList"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAssetStatementOfFinancialPositionExtensibleList_dcd86b5d-393f-4aa4-938a-e84131308f87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_4c7047d9-568a-43dd-bcf4-2fd01a86149a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_4c7047d9-568a-43dd-bcf4-2fd01a86149a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrentStatementOfFinancialPositionExtensibleList_ec0a84da-5ab1-4351-8a59-dd4cbdc77619" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrentStatementOfFinancialPositionExtensibleList"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrentStatementOfFinancialPositionExtensibleList_ec0a84da-5ab1-4351-8a59-dd4cbdc77619" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_b9d1f07b-239c-4096-bf9f-eb83f866804b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_b9d1f07b-239c-4096-bf9f-eb83f866804b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrentStatementOfFinancialPositionExtensibleList_4ca9c56e-3ce8-4ad9-906f-b5198044fc6a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrentStatementOfFinancialPositionExtensibleList"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrentStatementOfFinancialPositionExtensibleList_4ca9c56e-3ce8-4ad9-906f-b5198044fc6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseCost_93483fa5-e3a0-422b-8543-c064ef3d6b94" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseCost"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:to="loc_us-gaap_OperatingLeaseCost_93483fa5-e3a0-422b-8543-c064ef3d6b94" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeasePayments_a4df5da5-5edb-4bcb-a6b0-d374912c2f8b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeasePayments"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:to="loc_us-gaap_OperatingLeasePayments_a4df5da5-5edb-4bcb-a6b0-d374912c2f8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_cb1f8a3a-cfe1-4b42-8411-e0fff1722866" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_065a95b1-ad70-4507-9c74-dc600188ba4d" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_cb1f8a3a-cfe1-4b42-8411-e0fff1722866" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/LeasedPropertiesLeasedPropertiesFutureMinimumLeasePaymentDetails" xlink:type="simple" xlink:href="dare-20201231.xsd#LeasedPropertiesLeasedPropertiesFutureMinimumLeasePaymentDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/LeasedPropertiesLeasedPropertiesFutureMinimumLeasePaymentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_7dfa733f-02d5-43ba-83cf-81c1751e4713" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_db3445c9-c20e-474b-b59d-79f4195d6b6b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_7dfa733f-02d5-43ba-83cf-81c1751e4713" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_db3445c9-c20e-474b-b59d-79f4195d6b6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_1db8d731-f834-4d8f-ad79-2a9be63b2acb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_7dfa733f-02d5-43ba-83cf-81c1751e4713" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_1db8d731-f834-4d8f-ad79-2a9be63b2acb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_c4db73f4-d60b-44a8-9bfd-351d78ffcf79" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_7dfa733f-02d5-43ba-83cf-81c1751e4713" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_c4db73f4-d60b-44a8-9bfd-351d78ffcf79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_fba7d557-94d7-4d42-9983-8245bc74f20d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_7dfa733f-02d5-43ba-83cf-81c1751e4713" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_fba7d557-94d7-4d42-9983-8245bc74f20d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_50f70388-84b3-4d07-b047-9263eab39ef6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_7dfa733f-02d5-43ba-83cf-81c1751e4713" xlink:to="loc_us-gaap_OperatingLeaseLiability_50f70388-84b3-4d07-b047-9263eab39ef6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/CommitmentsandContingencies" xlink:type="simple" xlink:href="dare-20201231.xsd#CommitmentsandContingencies"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/CommitmentsandContingencies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_47bfcff3-6dda-48dd-a53d-af4e5eab7e91" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsDisclosureTextBlock_3084ee41-3de2-4fb0-b5a6-dff240241e12" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_47bfcff3-6dda-48dd-a53d-af4e5eab7e91" xlink:to="loc_us-gaap_CommitmentsDisclosureTextBlock_3084ee41-3de2-4fb0-b5a6-dff240241e12" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/CommitmentsandContingenciesAdditionalInformationDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#CommitmentsandContingenciesAdditionalInformationDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/CommitmentsandContingenciesAdditionalInformationDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_4adaaa2d-49cd-47ee-a91e-e09003a2ff4a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_CommitmentsAndContingenciesTable_b33a1861-3e91-478d-84db-c21bbaaf1dc9" xlink:href="dare-20201231.xsd#dare_CommitmentsAndContingenciesTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_4adaaa2d-49cd-47ee-a91e-e09003a2ff4a" xlink:to="loc_dare_CommitmentsAndContingenciesTable_b33a1861-3e91-478d-84db-c21bbaaf1dc9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_7c5f77cb-a86a-4e63-bfef-1ed3a4b7908c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesTable_b33a1861-3e91-478d-84db-c21bbaaf1dc9" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_7c5f77cb-a86a-4e63-bfef-1ed3a4b7908c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_a11a6dc9-fad5-4fe7-9b24-f42baeeb7415" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_7c5f77cb-a86a-4e63-bfef-1ed3a4b7908c" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_a11a6dc9-fad5-4fe7-9b24-f42baeeb7415" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_MicrochipsBiotechInc.Member_d71beec2-aa2c-46c7-a23a-7d8e7cb093d9" xlink:href="dare-20201231.xsd#dare_MicrochipsBiotechInc.Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_a11a6dc9-fad5-4fe7-9b24-f42baeeb7415" xlink:to="loc_dare_MicrochipsBiotechInc.Member_d71beec2-aa2c-46c7-a23a-7d8e7cb093d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_e843af38-443c-440a-81c1-eb5b39c5db6d" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesTable_b33a1861-3e91-478d-84db-c21bbaaf1dc9" xlink:to="loc_srt_RangeAxis_e843af38-443c-440a-81c1-eb5b39c5db6d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_ec049244-3572-4d36-adef-c51a0c12295b" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_e843af38-443c-440a-81c1-eb5b39c5db6d" xlink:to="loc_srt_RangeMember_ec049244-3572-4d36-adef-c51a0c12295b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_98e97a57-0035-4b97-bc68-e98d9ffb9814" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_ec049244-3572-4d36-adef-c51a0c12295b" xlink:to="loc_srt_MinimumMember_98e97a57-0035-4b97-bc68-e98d9ffb9814" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_fdf2bb5c-6666-4b81-8ef8-08c3ebd5f533" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_ec049244-3572-4d36-adef-c51a0c12295b" xlink:to="loc_srt_MaximumMember_fdf2bb5c-6666-4b81-8ef8-08c3ebd5f533" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_CommitmentsAndContingenciesLineItems_eb6db126-2b49-4532-8055-ea391cd958cb" xlink:href="dare-20201231.xsd#dare_CommitmentsAndContingenciesLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesTable_b33a1861-3e91-478d-84db-c21bbaaf1dc9" xlink:to="loc_dare_CommitmentsAndContingenciesLineItems_eb6db126-2b49-4532-8055-ea391cd958cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AssetAcquisitionContingentConsiderationCurrent_3897a7a6-79c8-456e-868e-f308d0d70225" xlink:href="dare-20201231.xsd#dare_AssetAcquisitionContingentConsiderationCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_eb6db126-2b49-4532-8055-ea391cd958cb" xlink:to="loc_dare_AssetAcquisitionContingentConsiderationCurrent_3897a7a6-79c8-456e-868e-f308d0d70225" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_CoronavirusAidReliefandEconomicSecurityActLoanProceedsReceived_69efc6e7-2959-419e-ad88-a79e33a9c569" xlink:href="dare-20201231.xsd#dare_CoronavirusAidReliefandEconomicSecurityActLoanProceedsReceived"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_eb6db126-2b49-4532-8055-ea391cd958cb" xlink:to="loc_dare_CoronavirusAidReliefandEconomicSecurityActLoanProceedsReceived_69efc6e7-2959-419e-ad88-a79e33a9c569" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_NotesPayableCurrentPlusAccruedInterest_c19eac05-6fb5-40d1-83d6-f757972296f4" xlink:href="dare-20201231.xsd#dare_NotesPayableCurrentPlusAccruedInterest"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_eb6db126-2b49-4532-8055-ea391cd958cb" xlink:to="loc_dare_NotesPayableCurrentPlusAccruedInterest_c19eac05-6fb5-40d1-83d6-f757972296f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_EmploymentAgreementSalaryPaymentReceivedUponTerminationWithoutCause_e023e0e7-e768-497c-996b-4bdb21536132" xlink:href="dare-20201231.xsd#dare_EmploymentAgreementSalaryPaymentReceivedUponTerminationWithoutCause"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_eb6db126-2b49-4532-8055-ea391cd958cb" xlink:to="loc_dare_EmploymentAgreementSalaryPaymentReceivedUponTerminationWithoutCause_e023e0e7-e768-497c-996b-4bdb21536132" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_EmploymentAgreementHealthBenefitsCoverageReceivedUponTerminationWithoutCause_02dc86a3-3b6d-4144-aa92-a17cee48d555" xlink:href="dare-20201231.xsd#dare_EmploymentAgreementHealthBenefitsCoverageReceivedUponTerminationWithoutCause"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_eb6db126-2b49-4532-8055-ea391cd958cb" xlink:to="loc_dare_EmploymentAgreementHealthBenefitsCoverageReceivedUponTerminationWithoutCause_02dc86a3-3b6d-4144-aa92-a17cee48d555" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_EmploymentAgreementChangeInControlOfCompanyTerminationForCauseOrGoodReason_521a7008-61cd-4aef-8050-dabb38a54ed8" xlink:href="dare-20201231.xsd#dare_EmploymentAgreementChangeInControlOfCompanyTerminationForCauseOrGoodReason"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_eb6db126-2b49-4532-8055-ea391cd958cb" xlink:to="loc_dare_EmploymentAgreementChangeInControlOfCompanyTerminationForCauseOrGoodReason_521a7008-61cd-4aef-8050-dabb38a54ed8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_EmploymentAgreementSalaryPaymentReceivedUponTerminationForCauseOrGoodReason_254e4b31-334e-4869-ab5d-0056b91a964f" xlink:href="dare-20201231.xsd#dare_EmploymentAgreementSalaryPaymentReceivedUponTerminationForCauseOrGoodReason"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_eb6db126-2b49-4532-8055-ea391cd958cb" xlink:to="loc_dare_EmploymentAgreementSalaryPaymentReceivedUponTerminationForCauseOrGoodReason_254e4b31-334e-4869-ab5d-0056b91a964f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_EmploymentAgreementHealthBenefitsCoverageReceivedUponTerminationForCauseOrGoodReason_839a3f0c-f4f6-49c2-b00b-a53d4b633855" xlink:href="dare-20201231.xsd#dare_EmploymentAgreementHealthBenefitsCoverageReceivedUponTerminationForCauseOrGoodReason"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_eb6db126-2b49-4532-8055-ea391cd958cb" xlink:to="loc_dare_EmploymentAgreementHealthBenefitsCoverageReceivedUponTerminationForCauseOrGoodReason_839a3f0c-f4f6-49c2-b00b-a53d4b633855" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedContributionPlanEmployerMatchingContributionPercent_c10ca718-16b1-4262-97ed-e59d740268b2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedContributionPlanEmployerMatchingContributionPercent"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_eb6db126-2b49-4532-8055-ea391cd958cb" xlink:to="loc_us-gaap_DefinedContributionPlanEmployerMatchingContributionPercent_c10ca718-16b1-4262-97ed-e59d740268b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedContributionPlanEmployerDiscretionaryContributionAmount_e5353d4e-be28-49bc-8388-31f4c98dd788" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DefinedContributionPlanEmployerDiscretionaryContributionAmount"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dare_CommitmentsAndContingenciesLineItems_eb6db126-2b49-4532-8055-ea391cd958cb" xlink:to="loc_us-gaap_DefinedContributionPlanEmployerDiscretionaryContributionAmount_e5353d4e-be28-49bc-8388-31f4c98dd788" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/GrantAwards" xlink:type="simple" xlink:href="dare-20201231.xsd#GrantAwards"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/GrantAwards" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesAbstract_43e98aab-f853-4fd9-a8b8-8869fdb8b8ba" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReceivablesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_GrantAwardTextBlock_f0f0fea3-f461-45f6-86d2-2ed25f6e6382" xlink:href="dare-20201231.xsd#dare_GrantAwardTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_43e98aab-f853-4fd9-a8b8-8869fdb8b8ba" xlink:to="loc_dare_GrantAwardTextBlock_f0f0fea3-f461-45f6-86d2-2ed25f6e6382" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/GrantAwardsAdditionalInformationDetails" xlink:type="simple" xlink:href="dare-20201231.xsd#GrantAwardsAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/GrantAwardsAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesAbstract_0de93787-2523-4e71-a36e-5b527d4a82eb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ReceivablesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_230b5839-1f81-478c-b1ea-4b5d34067726" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_0de93787-2523-4e71-a36e-5b527d4a82eb" xlink:to="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_230b5839-1f81-478c-b1ea-4b5d34067726" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_9822203f-e8c9-45e1-9123-e9c86b1de982" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_230b5839-1f81-478c-b1ea-4b5d34067726" xlink:to="loc_srt_ProductOrServiceAxis_9822203f-e8c9-45e1-9123-e9c86b1de982" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_9268952a-1809-4aa4-a970-9ceca8f32c4f" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_9822203f-e8c9-45e1-9123-e9c86b1de982" xlink:to="loc_srt_ProductsAndServicesDomain_9268952a-1809-4aa4-a970-9ceca8f32c4f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_GrantOvapreneMember_a7acd292-54df-44de-9fb4-85d11458916b" xlink:href="dare-20201231.xsd#dare_GrantOvapreneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_9268952a-1809-4aa4-a970-9ceca8f32c4f" xlink:to="loc_dare_GrantOvapreneMember_a7acd292-54df-44de-9fb4-85d11458916b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_GrantDAREFRT1Member_2ef26fe2-75f1-4895-af88-9fba7374d9e5" xlink:href="dare-20201231.xsd#dare_GrantDAREFRT1Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_9268952a-1809-4aa4-a970-9ceca8f32c4f" xlink:to="loc_dare_GrantDAREFRT1Member_2ef26fe2-75f1-4895-af88-9fba7374d9e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrantMember_9fbf847d-da97-47ed-a2ab-87b3e83fa0e4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GrantMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_9268952a-1809-4aa4-a970-9ceca8f32c4f" xlink:to="loc_us-gaap_GrantMember_9fbf847d-da97-47ed-a2ab-87b3e83fa0e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_c0ee38cb-7d52-44e1-b69e-64d96762e0a3" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_230b5839-1f81-478c-b1ea-4b5d34067726" xlink:to="loc_srt_CounterpartyNameAxis_c0ee38cb-7d52-44e1-b69e-64d96762e0a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_a0a99d58-6f92-4dbb-bb5f-b324bd8f7754" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_c0ee38cb-7d52-44e1-b69e-64d96762e0a3" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_a0a99d58-6f92-4dbb-bb5f-b324bd8f7754" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_BillAndMelindaGatesFoundationMember_e687bd76-1f0c-4851-b01a-de2dd8d9be5c" xlink:href="dare-20201231.xsd#dare_BillAndMelindaGatesFoundationMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_a0a99d58-6f92-4dbb-bb5f-b324bd8f7754" xlink:to="loc_dare_BillAndMelindaGatesFoundationMember_e687bd76-1f0c-4851-b01a-de2dd8d9be5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_6ab4ccd6-27de-4c9a-a8fa-23785b3f548d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountsNotesAndLoansReceivableLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_230b5839-1f81-478c-b1ea-4b5d34067726" xlink:to="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_6ab4ccd6-27de-4c9a-a8fa-23785b3f548d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ProceedsFromAwardOfGrant_2316050c-b2e4-4f99-a13b-c1c90f9b00ee" xlink:href="dare-20201231.xsd#dare_ProceedsFromAwardOfGrant"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_6ab4ccd6-27de-4c9a-a8fa-23785b3f548d" xlink:to="loc_dare_ProceedsFromAwardOfGrant_2316050c-b2e4-4f99-a13b-c1c90f9b00ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementWithFederalGovernmentCustomerFundingToOffsetCostsIncurred_42c27afd-fc05-4efd-9d00-a63c549287b0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementWithFederalGovernmentCustomerFundingToOffsetCostsIncurred"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_6ab4ccd6-27de-4c9a-a8fa-23785b3f548d" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementWithFederalGovernmentCustomerFundingToOffsetCostsIncurred_42c27afd-fc05-4efd-9d00-a63c549287b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrantsReceivable_fcbbbf46-9061-4f87-99b1-f36cf151752f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GrantsReceivable"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_6ab4ccd6-27de-4c9a-a8fa-23785b3f548d" xlink:to="loc_us-gaap_GrantsReceivable_fcbbbf46-9061-4f87-99b1-f36cf151752f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AdditionalPotentialFundingRelatedToGrantAward_f5f03d7d-6d83-47a9-bfa8-6936e2da5f3f" xlink:href="dare-20201231.xsd#dare_AdditionalPotentialFundingRelatedToGrantAward"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_6ab4ccd6-27de-4c9a-a8fa-23785b3f548d" xlink:to="loc_dare_AdditionalPotentialFundingRelatedToGrantAward_f5f03d7d-6d83-47a9-bfa8-6936e2da5f3f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ReceivableForExpensesEligibleForReimbursement_0bb67366-4b7e-4c12-ba71-91d4ca31d2bd" xlink:href="dare-20201231.xsd#dare_ReceivableForExpensesEligibleForReimbursement"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_6ab4ccd6-27de-4c9a-a8fa-23785b3f548d" xlink:to="loc_dare_ReceivableForExpensesEligibleForReimbursement_0bb67366-4b7e-4c12-ba71-91d4ca31d2bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_7b376a77-0bcb-4297-a523-fb541c7e51af" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_6ab4ccd6-27de-4c9a-a8fa-23785b3f548d" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_7b376a77-0bcb-4297-a523-fb541c7e51af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_DeferredGrantFundingCurrent_8b3e96f7-1cfa-4207-8620-d68da0018ceb" xlink:href="dare-20201231.xsd#dare_DeferredGrantFundingCurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_6ab4ccd6-27de-4c9a-a8fa-23785b3f548d" xlink:to="loc_dare_DeferredGrantFundingCurrent_8b3e96f7-1cfa-4207-8620-d68da0018ceb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/SubsequentEvents" xlink:type="simple" xlink:href="dare-20201231.xsd#SubsequentEvents"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/SubsequentEvents" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_2fffb3ea-691c-4f3e-b73b-e0615ab4137f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsTextBlock_9b5a39d3-e60e-4112-ab02-0a5104d088f1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_2fffb3ea-691c-4f3e-b73b-e0615ab4137f" xlink:to="loc_us-gaap_SubsequentEventsTextBlock_9b5a39d3-e60e-4112-ab02-0a5104d088f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://darebioscience.com/role/SubsequentEventsAdditionalInformationDetail" xlink:type="simple" xlink:href="dare-20201231.xsd#SubsequentEventsAdditionalInformationDetail"/>
  <link:presentationLink xlink:role="http://darebioscience.com/role/SubsequentEventsAdditionalInformationDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventsAbstract_bb88bc07-432c-4d57-9fe3-cf274be497ba" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTable_1e53e755-5204-46c8-82ed-563ddb15ecb4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_bb88bc07-432c-4d57-9fe3-cf274be497ba" xlink:to="loc_us-gaap_SubsequentEventTable_1e53e755-5204-46c8-82ed-563ddb15ecb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_63676522-d548-4d1f-b33c-c671b083e300" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_1e53e755-5204-46c8-82ed-563ddb15ecb4" xlink:to="loc_srt_ProductOrServiceAxis_63676522-d548-4d1f-b33c-c671b083e300" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_29d25deb-842d-413a-9488-9d3207bdd5f1" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_63676522-d548-4d1f-b33c-c671b083e300" xlink:to="loc_srt_ProductsAndServicesDomain_29d25deb-842d-413a-9488-9d3207bdd5f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_ATMSalesMember_eff3e682-50ff-4d81-b507-3da70225a5a3" xlink:href="dare-20201231.xsd#dare_ATMSalesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_29d25deb-842d-413a-9488-9d3207bdd5f1" xlink:to="loc_dare_ATMSalesMember_eff3e682-50ff-4d81-b507-3da70225a5a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_dcc40bc8-6b8f-4586-a8d1-ed934f4a3290" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_1e53e755-5204-46c8-82ed-563ddb15ecb4" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_dcc40bc8-6b8f-4586-a8d1-ed934f4a3290" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_a4721c05-aaae-4f27-ac7f-caef0a3e3dff" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_dcc40bc8-6b8f-4586-a8d1-ed934f4a3290" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_a4721c05-aaae-4f27-ac7f-caef0a3e3dff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_6e9f45cb-290a-49e4-b28b-30944a87f6b1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_a4721c05-aaae-4f27-ac7f-caef0a3e3dff" xlink:to="loc_us-gaap_SubsequentEventMember_6e9f45cb-290a-49e4-b28b-30944a87f6b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_54f29985-06a7-419f-a4ab-185d39ce2a81" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_1e53e755-5204-46c8-82ed-563ddb15ecb4" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_54f29985-06a7-419f-a4ab-185d39ce2a81" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_61530543-aa63-4c4b-9a69-3d5b2ce78c4b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_54f29985-06a7-419f-a4ab-185d39ce2a81" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_61530543-aa63-4c4b-9a69-3d5b2ce78c4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantMember_e6daaddd-8db1-4b37-96e9-38f6eaecf6a7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WarrantMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_61530543-aa63-4c4b-9a69-3d5b2ce78c4b" xlink:to="loc_us-gaap_WarrantMember_e6daaddd-8db1-4b37-96e9-38f6eaecf6a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_a6e589e9-533c-449c-acb7-8a7babcf3af8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_1e53e755-5204-46c8-82ed-563ddb15ecb4" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_a6e589e9-533c-449c-acb7-8a7babcf3af8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_46f14973-b2d1-4d45-9920-b46d67bd30f0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_a6e589e9-533c-449c-acb7-8a7babcf3af8" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_46f14973-b2d1-4d45-9920-b46d67bd30f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_AtTheMarketEquityOfferingsMember_876f41d0-ca8d-4010-843c-8c9833f35be1" xlink:href="dare-20201231.xsd#dare_AtTheMarketEquityOfferingsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_46f14973-b2d1-4d45-9920-b46d67bd30f0" xlink:to="loc_dare_AtTheMarketEquityOfferingsMember_876f41d0-ca8d-4010-843c-8c9833f35be1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_PurchaseAgreementMember_8e80d872-898f-4de6-a6df-53d548975437" xlink:href="dare-20201231.xsd#dare_PurchaseAgreementMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_46f14973-b2d1-4d45-9920-b46d67bd30f0" xlink:to="loc_dare_PurchaseAgreementMember_8e80d872-898f-4de6-a6df-53d548975437" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_010d81d0-901d-44fe-9dc9-9884344c87aa" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_1e53e755-5204-46c8-82ed-563ddb15ecb4" xlink:to="loc_srt_CounterpartyNameAxis_010d81d0-901d-44fe-9dc9-9884344c87aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8f2efa83-51f8-4a18-b8a2-2ed320c2accf" xlink:href="http://xbrl.fasb.org/srt/2020/elts/srt-2020-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_010d81d0-901d-44fe-9dc9-9884344c87aa" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8f2efa83-51f8-4a18-b8a2-2ed320c2accf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_LincolnParkMember_5ca8bf4f-8469-4391-b632-2748deafae27" xlink:href="dare-20201231.xsd#dare_LincolnParkMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8f2efa83-51f8-4a18-b8a2-2ed320c2accf" xlink:to="loc_dare_LincolnParkMember_5ca8bf4f-8469-4391-b632-2748deafae27" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventLineItems_98dec015-e92f-494b-b402-4cb303af9f13" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SubsequentEventLineItems"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_1e53e755-5204-46c8-82ed-563ddb15ecb4" xlink:to="loc_us-gaap_SubsequentEventLineItems_98dec015-e92f-494b-b402-4cb303af9f13" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_aae5779e-fda1-437d-a909-cf759c3b13b0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_98dec015-e92f-494b-b402-4cb303af9f13" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_aae5779e-fda1-437d-a909-cf759c3b13b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_8fc4f843-a49b-46b8-b19e-b42f8df7e58c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_98dec015-e92f-494b-b402-4cb303af9f13" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_8fc4f843-a49b-46b8-b19e-b42f8df7e58c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SalesCommissionsAndFees_10738b80-06dd-4c4d-b037-a32d1c4726dc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SalesCommissionsAndFees"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_98dec015-e92f-494b-b402-4cb303af9f13" xlink:to="loc_us-gaap_SalesCommissionsAndFees_10738b80-06dd-4c4d-b037-a32d1c4726dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightOutstanding_fa9ca7bf-7bb0-47a7-8a91-bf4aae813bef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfWarrantOrRightOutstanding"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_98dec015-e92f-494b-b402-4cb303af9f13" xlink:to="loc_us-gaap_ClassOfWarrantOrRightOutstanding_fa9ca7bf-7bb0-47a7-8a91-bf4aae813bef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_aa03f494-e56b-440a-ba27-1aa771d947b9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_98dec015-e92f-494b-b402-4cb303af9f13" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_aa03f494-e56b-440a-ba27-1aa771d947b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dare_GrossProceedsFromOfferingOfCommonStockAndWarrants_d520f83f-7cb1-4c91-927f-509393d66ea1" xlink:href="dare-20201231.xsd#dare_GrossProceedsFromOfferingOfCommonStockAndWarrants"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_98dec015-e92f-494b-b402-4cb303af9f13" xlink:to="loc_dare_GrossProceedsFromOfferingOfCommonStockAndWarrants_d520f83f-7cb1-4c91-927f-509393d66ea1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
